We recently went through your article titled“Elimination of lymphatic filariasis:Where do we stand so far?”by Aashna Sinha et al[1].The authors have brought about relevant information regarding lymphatic filariasis ...We recently went through your article titled“Elimination of lymphatic filariasis:Where do we stand so far?”by Aashna Sinha et al[1].The authors have brought about relevant information regarding lymphatic filariasis focussing on history,diagnostic aspects,treatment strategies and various control measures.Lymphatic filariasis is a neglected parasitic infection affecting millions of people worldwide.展开更多
Rationale:Candida auris is a potential emerging pathogen among Candida and causes serious health threats globally.Patient concerns:We reported a case of vulvovaginal candidiasis caused by Candida auris.A 26-year-old f...Rationale:Candida auris is a potential emerging pathogen among Candida and causes serious health threats globally.Patient concerns:We reported a case of vulvovaginal candidiasis caused by Candida auris.A 26-year-old female presented with complaints of vaginal discharge,itching and low back pain.Diagnosis:High vaginal swab culture yielded Candida.The strain was confirmed as Candida auris by amplification and sequencing the internal transcribed spacer region.Antifungal susceptibility testing revealed that the isolate was resistant to fluconazole,amphotericin B and clotrimazole and susceptible to ketoconazole and nystatin.The isolate also exhibited biofilm forming ability.Interventions:Her symptoms did not subside with initial management with fluconazole and clotrimazole.Later,she was started on ketoconazole therapy.The patient responded well to ketoconazole.Outcome and lessons:To the best of our knowledge,this is the first report about the presence of a drug resistant biofilm forming Candida auris strain isolated from a vaginal swab sample from Chennai area.Biofilm forming ability might contribute to its drug resistance.Nucleic acid analysis helps in rapid and accurate identification of such rare species.展开更多
文摘We recently went through your article titled“Elimination of lymphatic filariasis:Where do we stand so far?”by Aashna Sinha et al[1].The authors have brought about relevant information regarding lymphatic filariasis focussing on history,diagnostic aspects,treatment strategies and various control measures.Lymphatic filariasis is a neglected parasitic infection affecting millions of people worldwide.
基金Financial support to PN from the Department of Biotechnology(DBT),Ministry of science and Technology,New Delhi(BT/PR/23592/MED/29/1203/2017)
文摘Rationale:Candida auris is a potential emerging pathogen among Candida and causes serious health threats globally.Patient concerns:We reported a case of vulvovaginal candidiasis caused by Candida auris.A 26-year-old female presented with complaints of vaginal discharge,itching and low back pain.Diagnosis:High vaginal swab culture yielded Candida.The strain was confirmed as Candida auris by amplification and sequencing the internal transcribed spacer region.Antifungal susceptibility testing revealed that the isolate was resistant to fluconazole,amphotericin B and clotrimazole and susceptible to ketoconazole and nystatin.The isolate also exhibited biofilm forming ability.Interventions:Her symptoms did not subside with initial management with fluconazole and clotrimazole.Later,she was started on ketoconazole therapy.The patient responded well to ketoconazole.Outcome and lessons:To the best of our knowledge,this is the first report about the presence of a drug resistant biofilm forming Candida auris strain isolated from a vaginal swab sample from Chennai area.Biofilm forming ability might contribute to its drug resistance.Nucleic acid analysis helps in rapid and accurate identification of such rare species.
