Objectives:To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes.Methods:This retrospective observational single-center study was conduc...Objectives:To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes.Methods:This retrospective observational single-center study was conducted in a tertiary care hospital in Vidisha district,India.COVID-19 patients were included in this study,who were admitted to ICU and the COVID Care Centre from August 2020 to October 2020.Demographic profile,clinical characteristics,medical history,A-DROP score,complete blood counts including lymphocyte counts(on admission),the severity of the disease course,and duration of hospitalization were collected.The correlation between lymphopenia and A-DROP score was determined,and their role in predicting poor outcomes was investigated.Results:This study included 220 patients,among which 134 were male,and 86 were female[mean age(48.98±16.98)years,95%CI:46.72-51.23].Lymphocyte count in COVID-19 patients negatively correlated with the A-DROP score(r=-0.67,P<0.001).The area under the ROC curve was 0.892(95%CI:0.80-0.98,P<0.001)for the lymphocyte count,and the area under the ROC curve was 0.93(95%CI:0.84-1.00,P<0.001)for lymphocyte count-A-DROP.Conclusion:Lymphocyte count along with the A-DROP score on admission could be used to predict the severity of COVID-19 pneumonia and unfavorable outcome.展开更多
文摘Objectives:To determine the correlation between lymphocyte count and A-DROP score in COVID-19 patients and their role in predicting poor outcomes.Methods:This retrospective observational single-center study was conducted in a tertiary care hospital in Vidisha district,India.COVID-19 patients were included in this study,who were admitted to ICU and the COVID Care Centre from August 2020 to October 2020.Demographic profile,clinical characteristics,medical history,A-DROP score,complete blood counts including lymphocyte counts(on admission),the severity of the disease course,and duration of hospitalization were collected.The correlation between lymphopenia and A-DROP score was determined,and their role in predicting poor outcomes was investigated.Results:This study included 220 patients,among which 134 were male,and 86 were female[mean age(48.98±16.98)years,95%CI:46.72-51.23].Lymphocyte count in COVID-19 patients negatively correlated with the A-DROP score(r=-0.67,P<0.001).The area under the ROC curve was 0.892(95%CI:0.80-0.98,P<0.001)for the lymphocyte count,and the area under the ROC curve was 0.93(95%CI:0.84-1.00,P<0.001)for lymphocyte count-A-DROP.Conclusion:Lymphocyte count along with the A-DROP score on admission could be used to predict the severity of COVID-19 pneumonia and unfavorable outcome.
