Background: Digital myxoid cysts (DMC) are often unsightly; theymay cause nail dystrophy and are sometimes painful. There is a multitude of existing therapies and recurrences are not uncommon; some treatments may be p...Background: Digital myxoid cysts (DMC) are often unsightly; theymay cause nail dystrophy and are sometimes painful. There is a multitude of existing therapies and recurrences are not uncommon; some treatments may be painful or result in scarring. Infrared coagulation (IRC) produces predictable thermal injury with relative sparing of superficial tissues and represents an alternative treatment modality in DMC. Objectives: To assess the outcome of treatment of DMC with IRC. Methods: Twenty- two patients with DMC treated with IRC were identified retrospectively (23 DMC: 18 finger and five toe). IRC was delivered to the area of the cyst under local anaesthesia. Results: Of the 23 lesions treated with IRC 86% responded; these included 73% that resolved after a single treatment, one lesion that relapsed after 3 years, one lesion that was reduced in size and one lesion that required three treatments over 18 months but has not recurred over the subsequent 9 years. There were three early recurrences that required treatment with other modalities: two were successfully treated with surgery and one responded to a single treatment with cryo- therapy. One patient was excluded from the analysis because it was not possible to assess her adequately. Conclusions: We present long- term follow- up data (mean follow- up 4.8 years, range 10 months- 10.5 years) of the treatment of DMC with IRC. Treatment was well tolerated, with few side- effects, and cosmetic outcomewas excellent. While recurrence rates were similar to many existing therapies, the ease of delivery, tolerability and cosmetic results make IRC a favourable option for the treatment of DMC.展开更多
Pyoderma gangrenosum (PG) is associated with a number of systemic diseases. PG in association with hidradenitis suppurativa (HS) has been rarely reported. We describe six patients (three men, three women; aged 35- 51 ...Pyoderma gangrenosum (PG) is associated with a number of systemic diseases. PG in association with hidradenitis suppurativa (HS) has been rarely reported. We describe six patients (three men, three women; aged 35- 51 years),who developed PG on a background of HS. The onset of PG occurred only after HS had been present for at least two decades. No relationship in disease activity between the two conditions was observed. Three patients described previous severe adolescent acne vulgaris, one had concurrent systemic lupus erythematosus and another had chronic iron- deficiency anaemia. The course of PG was severe and refractory in four patients,who required treatment including high- dose oral corticosteroids, ciclosporin, intravenous immunoglobulin and intravenous cyclophosphamide.展开更多
文摘Background: Digital myxoid cysts (DMC) are often unsightly; theymay cause nail dystrophy and are sometimes painful. There is a multitude of existing therapies and recurrences are not uncommon; some treatments may be painful or result in scarring. Infrared coagulation (IRC) produces predictable thermal injury with relative sparing of superficial tissues and represents an alternative treatment modality in DMC. Objectives: To assess the outcome of treatment of DMC with IRC. Methods: Twenty- two patients with DMC treated with IRC were identified retrospectively (23 DMC: 18 finger and five toe). IRC was delivered to the area of the cyst under local anaesthesia. Results: Of the 23 lesions treated with IRC 86% responded; these included 73% that resolved after a single treatment, one lesion that relapsed after 3 years, one lesion that was reduced in size and one lesion that required three treatments over 18 months but has not recurred over the subsequent 9 years. There were three early recurrences that required treatment with other modalities: two were successfully treated with surgery and one responded to a single treatment with cryo- therapy. One patient was excluded from the analysis because it was not possible to assess her adequately. Conclusions: We present long- term follow- up data (mean follow- up 4.8 years, range 10 months- 10.5 years) of the treatment of DMC with IRC. Treatment was well tolerated, with few side- effects, and cosmetic outcomewas excellent. While recurrence rates were similar to many existing therapies, the ease of delivery, tolerability and cosmetic results make IRC a favourable option for the treatment of DMC.
文摘Pyoderma gangrenosum (PG) is associated with a number of systemic diseases. PG in association with hidradenitis suppurativa (HS) has been rarely reported. We describe six patients (three men, three women; aged 35- 51 years),who developed PG on a background of HS. The onset of PG occurred only after HS had been present for at least two decades. No relationship in disease activity between the two conditions was observed. Three patients described previous severe adolescent acne vulgaris, one had concurrent systemic lupus erythematosus and another had chronic iron- deficiency anaemia. The course of PG was severe and refractory in four patients,who required treatment including high- dose oral corticosteroids, ciclosporin, intravenous immunoglobulin and intravenous cyclophosphamide.
