Prognostic value of alcohol consumptionand some other dietary habits for survival in a cohort of Chinese men with lung cancer

Background:Alcohol consumption and some other dietary habits are thought to be associated with lung cancer incidence.However,the effects of these habits on lung cancer prognosis have been studied rarely.The purpose of this study was to address these gaps in knowledge.Methods:We studied a cohort of 1052 Chinese men in Hong Kong who were diagnosed with primary lung cancer.Cox proportional hazards models were used to determine the prognostic values of consumption of alcohol,fresh fruits or vegetables,meat,and fried or preserved food.Results:Compared with never drinkers,men who drank alcohol 1-3 days per week had a more favorable lung cancer prognosis(hazard ratio[HR]:0.82,95%confidence interval[CI]0.68-0.97);however,this survival advantage was not significant in men who drank alcohol more frequently(HR:0.91,95%CI 0.73-1.14).Compared with men who consumed preserved or fried food only occasionally,men who consumed these foods frequently had a higher risk of lung cancer mortality(HR:1.20,95%CI 1.00-1.42).Conclusions:Occasional consumption of alcohol was a favorable survival factor for Chinese men with lung cancer.However,this survival benefit did not exist for frequent drinkers of alcohol.Chinese men with lung cancer who were frequent consumers of fried or preserved food had a worse prognosis than those who consumed these foods only occasionally.

饮酒和其他饮食习惯对中国男性肺癌患者生存的预后价值

背景与目的肺癌的发病率与饮酒和其他饮食习惯有关,但这些习惯对肺癌预后的影响却鲜有研究。本研究旨对这些未知问题进行探讨。方法我们对1052例在香港的诊断为原发性肺癌的中国男性患者进行了队列研究。采用Cox比例风险模型分析食用酒精、新鲜水果或蔬菜、肉类、油炸或腌制食品对肺癌患者预后的影响。结果与从不饮酒的患者相比,每周饮酒1–3天的男性肺癌患者预后更好(风险比[hazard ratio,HR]=0.82,95%置信区间[confidence interval,CI]:0.68–0.97),但这种生存优势在饮酒频率更高的男性患者中不显著(HR=0.91,95%CI:0.73–1.14)。与偶尔食用腌制或油炸食品的男性相比,频繁食用这些食品的男性肺癌死亡率更高(HR=1.20,95%CI:1.00–1.42)。结论偶尔饮酒是中国男性肺癌患者延长生存期的有利因素,但对于频繁饮酒的患者却不存在这样的作用。频繁食用油炸食品或腌制食品的中国男性肺癌患者比偶尔食用这些食品的患者预后更差。