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Pigmented well-differentiated hepatocellular neoplasm with β-catenin mutation
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作者 lara neves souza Rodrigo Bronze de Martino +3 位作者 Richard Thompson Sandra Strautnieks Nigel D Heaton Alberto Quaglia 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2015年第6期660-664,共5页
ABSTRACT: According to the most recent WHO classification of hepatocellular adenomas, a small percentage of inflammatory hepatocellular adenomas presents with mutation in the β-catenin gene and are at higher risk of... ABSTRACT: According to the most recent WHO classification of hepatocellular adenomas, a small percentage of inflammatory hepatocellular adenomas presents with mutation in the β-catenin gene and are at higher risk of malignant transformation. It has been recognized that adenoma-like hepatocellular neoplasms with focal atypia, or in unusual clinical context present with similar cytogenetic and immunohistochemistry characteristics to well-differentiated hepatocellular carcino- mas. 展开更多
关键词 hepatocellular adenoma hepatocellular carcinoma Β-CATENIN glutamine synthetase DIETHYLSTILBESTROL
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