<b><span style="font-family:Verdana;">Introduction:</span></b><span style="font-family:Verdana;"> Lymphatic filariasis (LF) and malaria are two vector-borne</span&g...<b><span style="font-family:Verdana;">Introduction:</span></b><span style="font-family:Verdana;"> Lymphatic filariasis (LF) and malaria are two vector-borne</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> diseases which parasites can simultaneously infect human or mosquito. In Burkina Faso, studies mainly focused on the control of these diseases independently. Hence, there is a lack of information on their co-transmission of to both human and vector. The present study aimed at providing baseline data </span><span style="font-family:Verdana;">from endemic areas in Burkina Faso towards a successful integrated man</span><span><span style="font-family:Verdana;">agement of both diseases. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> The study was carried out in six sites</span></span><span style="font-family:Verdana;"> dist</span><span style="font-family:Verdana;">ributed in the East, Center-East and South-West regions of Burkina Faso. </span><span style="font-family:Verdana;">Data were collected in August 2014 and September 2015. The infection rates in human and vector populations, vector diversity, trophic and resting behavior were investigated. To determine the disease prevalence nocturnal finger-</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">p</span><span style="font-family:Verdana;">rick blood sample and microscopic observations were performed. Vect</span><span style="font-family:Verdana;">ors </span><span style="font-family:Verdana;">collected by human landing catches and pyrethrum spray collections. Bio</span><span style="font-family:Verdana;">chemical and molecular analyses were performed to identify <i></i></span><i><i><span style="font-family:Verdana;">Anopheles gam</span><span><span style="font-family:Verdana;">biae </span><span style="font-family:Verdana;">sensu lato</span></span></i></i></span><b><span> </span></b><span style="font-family:Verdana;">sibling species, and to determine vector infection rate and</span><span style="font-family:Verdana;"> their blood meal origins. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Results indicate residual transmission of LF and malaria in human and vector populations. A low co-infection rate (<1%) with <i></i></span><i><i><span style="font-family:Verdana;">Wuchereria bancrofti</span></i></i><span style="font-family:Verdana;"> and <i></i></span><i><i><span style="font-family:Verdana;">Plasmodium falciparum</span></i></i><span style="font-family:Verdana;"> was noted in both human and mosquito. <i></i></span><i><i><span style="font-family:Verdana;">Anopheles gambiae s.l.</span></i><span> </span><i><span style="font-family:Verdana;"></span></i></i><span style="font-family:;" "=""><span style="font-family:Verdana;">, <i></i></span><i><i><span style="font-family:Verdana;">An. funestus s.l.</span></i></i></span><i><span> </span><i><span style="font-family:Verdana;"></span></i></i><span style="font-family:;" "=""><span style="font-family:Verdana;"> and <i></i></span><i><i><span style="font-family:Verdana;">An. nili</span></i></i></span><span style="font-family:Verdana;"> were by order the main potential vectors encountered. It was in majority parous females and exhibited endophagic and exophagic behavior. Parasite’s co-infec</span><span style="font-family:;" "=""><span style="font-family:Verdana;">tion was found with <i></i></span><i><i><span style="font-family:Verdana;">An. coluzzii</span></i></i></span><span style="font-family:Verdana;"> and <i></i></span><i><i><span style="font-family:Verdana;">An. nili</span></i></i><span style="font-family:Verdana;"> only. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The present study has provided basic information on the (co-)transmission of both diseases in the study areas. These results will be useful for further investigations towards the development and implementation of a better integrated strategy to control these diseases.</span>展开更多
文摘<b><span style="font-family:Verdana;">Introduction:</span></b><span style="font-family:Verdana;"> Lymphatic filariasis (LF) and malaria are two vector-borne</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> diseases which parasites can simultaneously infect human or mosquito. In Burkina Faso, studies mainly focused on the control of these diseases independently. Hence, there is a lack of information on their co-transmission of to both human and vector. The present study aimed at providing baseline data </span><span style="font-family:Verdana;">from endemic areas in Burkina Faso towards a successful integrated man</span><span><span style="font-family:Verdana;">agement of both diseases. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> The study was carried out in six sites</span></span><span style="font-family:Verdana;"> dist</span><span style="font-family:Verdana;">ributed in the East, Center-East and South-West regions of Burkina Faso. </span><span style="font-family:Verdana;">Data were collected in August 2014 and September 2015. The infection rates in human and vector populations, vector diversity, trophic and resting behavior were investigated. To determine the disease prevalence nocturnal finger-</span></span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">p</span><span style="font-family:Verdana;">rick blood sample and microscopic observations were performed. Vect</span><span style="font-family:Verdana;">ors </span><span style="font-family:Verdana;">collected by human landing catches and pyrethrum spray collections. Bio</span><span style="font-family:Verdana;">chemical and molecular analyses were performed to identify <i></i></span><i><i><span style="font-family:Verdana;">Anopheles gam</span><span><span style="font-family:Verdana;">biae </span><span style="font-family:Verdana;">sensu lato</span></span></i></i></span><b><span> </span></b><span style="font-family:Verdana;">sibling species, and to determine vector infection rate and</span><span style="font-family:Verdana;"> their blood meal origins. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Results indicate residual transmission of LF and malaria in human and vector populations. A low co-infection rate (<1%) with <i></i></span><i><i><span style="font-family:Verdana;">Wuchereria bancrofti</span></i></i><span style="font-family:Verdana;"> and <i></i></span><i><i><span style="font-family:Verdana;">Plasmodium falciparum</span></i></i><span style="font-family:Verdana;"> was noted in both human and mosquito. <i></i></span><i><i><span style="font-family:Verdana;">Anopheles gambiae s.l.</span></i><span> </span><i><span style="font-family:Verdana;"></span></i></i><span style="font-family:;" "=""><span style="font-family:Verdana;">, <i></i></span><i><i><span style="font-family:Verdana;">An. funestus s.l.</span></i></i></span><i><span> </span><i><span style="font-family:Verdana;"></span></i></i><span style="font-family:;" "=""><span style="font-family:Verdana;"> and <i></i></span><i><i><span style="font-family:Verdana;">An. nili</span></i></i></span><span style="font-family:Verdana;"> were by order the main potential vectors encountered. It was in majority parous females and exhibited endophagic and exophagic behavior. Parasite’s co-infec</span><span style="font-family:;" "=""><span style="font-family:Verdana;">tion was found with <i></i></span><i><i><span style="font-family:Verdana;">An. coluzzii</span></i></i></span><span style="font-family:Verdana;"> and <i></i></span><i><i><span style="font-family:Verdana;">An. nili</span></i></i><span style="font-family:Verdana;"> only. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> The present study has provided basic information on the (co-)transmission of both diseases in the study areas. These results will be useful for further investigations towards the development and implementation of a better integrated strategy to control these diseases.</span>