Traumatic brain injury(TBI) represents a significant cause of disability worldwide.It creates a vast array of damaging macro-and microscopic changes in the affected brain area(s),ranging from neuronal cell death,chang...Traumatic brain injury(TBI) represents a significant cause of disability worldwide.It creates a vast array of damaging macro-and microscopic changes in the affected brain area(s),ranging from neuronal cell death,changes in structural spine integrity and dynamics to axonal injury and ove rall neuronal circuit disruption,ultimately leading to functional and cognitive deficits in both humans and animal models(N udo,2013).展开更多
基金supported by grants from the Deutsche Forschungsgem einschoft (DFGTRR274/1+6 种基金ID 408885537Project C03)the Wings for Lifethe Humboldt foundationsupported by the Munich Center for Systems Neurology (DFGSyNergyEXC 2145/ID390857198)
文摘Traumatic brain injury(TBI) represents a significant cause of disability worldwide.It creates a vast array of damaging macro-and microscopic changes in the affected brain area(s),ranging from neuronal cell death,changes in structural spine integrity and dynamics to axonal injury and ove rall neuronal circuit disruption,ultimately leading to functional and cognitive deficits in both humans and animal models(N udo,2013).