Immunoglobulin A(Iga)-isotype antibodies play an important role in immunity owing to their structure,glycosylation,localization and receptor interactions.Dysfunctions in this system can lead to multiple types of patho...Immunoglobulin A(Iga)-isotype antibodies play an important role in immunity owing to their structure,glycosylation,localization and receptor interactions.Dysfunctions in this system can lead to multiple types of pathology.This review describes the characteristics of Iga and discusses the involvement of abnormalities in the Iga system on the development of celiac disease and Iga nephropathy.展开更多
文摘Immunoglobulin A(Iga)-isotype antibodies play an important role in immunity owing to their structure,glycosylation,localization and receptor interactions.Dysfunctions in this system can lead to multiple types of pathology.This review describes the characteristics of Iga and discusses the involvement of abnormalities in the Iga system on the development of celiac disease and Iga nephropathy.
