Dengue virus,a member of the Flavivirus genus in the Flaviviridae family,has four serotypes(DEN-1 to DEN-4),and is responsible for both mild and severe dengue fever(dengue hemorrhagic fever and dengue shock syndrome)[...Dengue virus,a member of the Flavivirus genus in the Flaviviridae family,has four serotypes(DEN-1 to DEN-4),and is responsible for both mild and severe dengue fever(dengue hemorrhagic fever and dengue shock syndrome)[1].Dengue cases are under reported in India and the cases are treated clinically based on the clinical triage of symptoms[2].Nonstructural protein(NS1)antigen is a highly conserved glycoprotein found in Flavivirus group such as Dengue,Zika,and Japanese encephalitis virus.Simultaneous detection of NS1 antigen,IgM and IgG antibody in a single cassette is used for testing primary and secondary dengue infection.Early diagnosis of disease progression associated with severe dengue and accessibility to appropriate medical care reduces severe dengue fatality rates to less than 1%.This retrospective study,conducted from January 2021 to December 2021 in the tertiary care hospital,South India,was aimed to determine the seroprevalence of dengue adult patients with acute febrile illness.展开更多
文摘Dengue virus,a member of the Flavivirus genus in the Flaviviridae family,has four serotypes(DEN-1 to DEN-4),and is responsible for both mild and severe dengue fever(dengue hemorrhagic fever and dengue shock syndrome)[1].Dengue cases are under reported in India and the cases are treated clinically based on the clinical triage of symptoms[2].Nonstructural protein(NS1)antigen is a highly conserved glycoprotein found in Flavivirus group such as Dengue,Zika,and Japanese encephalitis virus.Simultaneous detection of NS1 antigen,IgM and IgG antibody in a single cassette is used for testing primary and secondary dengue infection.Early diagnosis of disease progression associated with severe dengue and accessibility to appropriate medical care reduces severe dengue fatality rates to less than 1%.This retrospective study,conducted from January 2021 to December 2021 in the tertiary care hospital,South India,was aimed to determine the seroprevalence of dengue adult patients with acute febrile illness.
