In contrast to the concurrent mixer-settler,the interaction between the mixing and settling chambers have to be taken into account in the simulation of the countercurrent mixer-settler,and no work has been reported fo...In contrast to the concurrent mixer-settler,the interaction between the mixing and settling chambers have to be taken into account in the simulation of the countercurrent mixer-settler,and no work has been reported for this equipment.In this work,a three-phase flow model based on the Eulerian multiphase model,coupled with a sliding mesh model is proposed for a countercurrent mixer-settler.Based on this,the dispersed phase distribution,flow pattern,and pressure distribution are investigated,which can help to fill the gap in the operation mechanism.In addition,the velocity vector distribution at the phase port shows an intriguing phenomenon that two types of vectors with opposite directions are distributed on the left and right sides of the same plane,which indicates that the material exchange in the mixing and settling chambers is simultaneous.Analysis of this variation at this location by a fast Fourier transform(FFT)method reveals that it is mainly influenced by the mixing chamber and is consistent with the main period of the outlet flow fluctuations.Therefore,by monitoring the fluctuation of the outlet flow and then analyzing it by the FFT method,the state of the whole tank can be determined,which makes it promising for the design of control systems for countercurrent mixer-settlers.展开更多
Probabilistic load forecasting(PLF)is able to present the uncertainty information of the future loads.It is the basis of stochastic power system planning and operation.Recent works on PLF mainly focus on how to develo...Probabilistic load forecasting(PLF)is able to present the uncertainty information of the future loads.It is the basis of stochastic power system planning and operation.Recent works on PLF mainly focus on how to develop and combine forecasting models,while the feature selection issue has not been thoroughly investigated for PLF.This paper fills the gap by proposing a feature selection method for PLF via sparse L1-norm penalized quantile regression.It can be viewed as an extension from point forecasting-based feature selection to probabilistic forecasting-based feature selection.Since both the number of training samples and the number of features to be selected are very large,the feature selection process is casted as a large-scale convex optimization problem.The alternating direction method of multipliers is applied to solve the problem in an efficient manner.We conduct case studies on the open datasets of ten areas.Numerical results show that the proposed feature selection method can improve the performance of the probabilistic forecasting and outperforms traditional least absolute shrinkage and selection operator method.展开更多
The resonant frequencies of the excited surface waves on a metal hole array with respect to the incident angle were studied in the terahertz region.The experimental and theoretical results demonstrate that the resonan...The resonant frequencies of the excited surface waves on a metal hole array with respect to the incident angle were studied in the terahertz region.The experimental and theoretical results demonstrate that the resonant peak of surface wave excitation splits into two when transmitted through a metal hole array off-normally.The high-order mode with resonant frequency above the cutoff frequency fc(plasma frequency effect)has a shorter attenuation length than that of the low-order mode whose resonant frequency is below fc.The reason is that the high-order mode is a coupled mode consisting of surface wave and hole modes,while the low-order mode is just an excited surface wave(which can be considered as the spoof surface plasmons).Our investigation may open a door to distinguish the spoof surface plasmons and the coupled modes of surface waves and hole modes.展开更多
With the deregulation of the electric power industry, electricity price forecasting plays an increasingly important role in electricity markets, especially for retailors and investment decision making. Month ahead ave...With the deregulation of the electric power industry, electricity price forecasting plays an increasingly important role in electricity markets, especially for retailors and investment decision making. Month ahead average daily electricity price profile forecasting is proposed for the first time in this paper. A hybrid nonlinear regression and support vector machine(SVM) model is proposed. Offpeak hours, peak hours in peak months and peak hours in off-peak months are distinguished and different methods are designed to improve the forecast accuracy. A nonlinear regression model with deviation compensation is proposed to forecast the prices of off-peak hours and peak hours in off-peak months. SVM is adopted to forecast the prices of peak hours in peak months. Case studies based on data from ERCOT validate the effectiveness of the proposed hybrid method.展开更多
Demand Response(DR)provides both operational and financial benefits to a variety of stakeholders in the power system.For example,in the deregulated market operated by the Electric Reliability Council of Texas(ERCOT),l...Demand Response(DR)provides both operational and financial benefits to a variety of stakeholders in the power system.For example,in the deregulated market operated by the Electric Reliability Council of Texas(ERCOT),load serving entities(LSEs)usually purchase electricity from the wholesale market(either in day-ahead or real-time market)and sign fixed retail price contracts with their end-consumers.Therefore,incentivizing end-consumers’load shift from peak to off-peak hours could benefit the LSE in terms of reducing its purchase of electricity under high prices from the real-time market.As the first-of-its-kind implementation of Coupon Incentive-based Demand Response(CIDR),the EnergyCoupon project provides end-consumers with dynamic time-of-use DR event announcements,individualized load reduction targets with EnergyCoupons as the incentive for meeting these targets,as well as periodic lotteries using these coupons as lottery tickets for winning dollar-value gifts.A number of methodologies are developed for this special type of DR program including price/baseline prediction,individualized target setting and a lottery mechanism.This paper summarizes the methodologies,design,critical findings,as well as the potential generalization of such an experiment.Comparison of the EnergyCoupon with a conventional Time-of-Use(TOU)price-based DR program is also conducted.Experimental results in the year 2017 show that by combining dynamic coupon offers with periodic lotteries,the effective cost for demand response providers in EnergyCoupon can be substantially reduced,while achieving a similar level of demand reduction as conventional DR programs.展开更多
The pathogenic factors of deafness are complex;more than 50%of cases are caused by genetic factors.Between 75%and 80%of cases of hereditary hearing impairment are autosomal recessive,15%to 25%are autosomal dominant,an...The pathogenic factors of deafness are complex;more than 50%of cases are caused by genetic factors.Between 75%and 80%of cases of hereditary hearing impairment are autosomal recessive,15%to 25%are autosomal dominant,and 1%to 2%are mitochondrial or X-linked.Cochlea implantation is the main method for treating severe and extremely severe bilateral sensorineural deafness and it is widely used in clinical treatment.As clinical cases of cochlea implantation accumulate,differences in the efficacy of implantation in individuals are emerging and attracting attention.In addition to residual hearing level,implantation age,and other factors,gene mutation is an important factor influencing postoperative rehabilitation in patients.With continuous progress in genetic testing technology for deafness,genetic diagnosis has become an important tool in preoperative evaluation and postoperative effect prediction in patients undergoing cochlear implantation.This article reviews the current status and future development of cochlear implantation in the treatment of hereditary deafness resulting from mutations in common deafness-causing genes.展开更多
As COVID-19 sweeps through the whole world,human activities have been changed significantly.Under such circumstances,the electricity sector is deeply affected and faced with great challenges.This paper provides a comp...As COVID-19 sweeps through the whole world,human activities have been changed significantly.Under such circumstances,the electricity sector is deeply affected and faced with great challenges.This paper provides a comprehensive review of the impacts that the pandemic has caused on the electricity sector.Electricity demand has dropped sharply as governments around the world executed lockdown restrictions,while the load composition and daily load profile have also changed.The share of renewable generation has increased against the decline of the total electricity generation.Changed power balance situation and increased uncertainty of demand have posed higher pressure on system operators,along with voltage violation issue and challenges for system maintenance and management.The electricity market is also substantially influenced,while longterm investment in clean energy is expected to be stable.The externality such as emission reduction is also discussed.展开更多
In this study,a machine learning based method is proposed for creating synthetic eventful phasor measurement unit(PMU)data under time-varying load conditions.The proposed method leverages generative adversarial networ...In this study,a machine learning based method is proposed for creating synthetic eventful phasor measurement unit(PMU)data under time-varying load conditions.The proposed method leverages generative adversarial networks to create quasi-steady states for the power system under slowly-varying load conditions and incorporates a framework of neural ordinary differential equations(ODEs)to capture the transient behaviors of the system during voltage oscillation events.A numerical example of a large power grid suggests that this method can create realistic synthetic eventful PMU voltage measurements based on the associated real PMU data without any knowledge of the underlying nonlinear dynamic equations.The results demonstrate that the synthetic voltage measurements have the key characteristics of real system behavior on distinct time scales.展开更多
For the planning,operation and control of multiterminal voltage source converter(VSC)based high-voltage direct current(HVDC)(VSC-MTDC)systems,an accurate power flow formulation is a key starting point.Conventional pow...For the planning,operation and control of multiterminal voltage source converter(VSC)based high-voltage direct current(HVDC)(VSC-MTDC)systems,an accurate power flow formulation is a key starting point.Conventional power flow formulations assume the constant frequencies for all asynchronous AC systems.Therefore,a new feature about the complex coupling relations between AC frequencies,DC voltages and the exchanged power via VSC stations cannot be characterized if VSC-MTDC systems are required to provide cross-regional frequency responses.To address this issue,this paper proposes a comprehensive frequency-dependent power flow formulation.The proposed approach takes the frequencies of asynchronous AC systems as explicit variables,and investigates the novel bus models of the interlinking buses of VSC stations.The proposed approach accommodates different operation modes and frequency droop strategies of VSC stations,and considers the power losses of VSC stations.The effectiveness and generality of the developed approach are validated by a 6-terminal VSC-HVDC test system.The test system presents the characteristics of the coexistence of numerous VSC operation modes,the absence of slack buses in both AC and DC subsystems,and diversified grid configurations such as point-to-point integration of renewable energy sources and one AC system integrated with multiple VSC stations.展开更多
This paper examines the impact of power transmission network topology change on locational marginal price(LMP) in real-time power markets. We consider the case where the false status of circuit breakers(CBs) that bypa...This paper examines the impact of power transmission network topology change on locational marginal price(LMP) in real-time power markets. We consider the case where the false status of circuit breakers(CBs) that bypass topology error processing can generate an incorrect power system network topology, subsequently distorting the results of the state estimation and economic dispatch.The main goal of this paper is to assess the economic impact of this misconfigured network topology on realtime LMP in an entire power system with network congestion. To this end, we start with our prior result, a simple and analytical congestion price equation, which can be applied to any single line congestion scenario. This equation can be extended to better understand the degree to which the LMP at any bus changes due to any line status error. Furthermore, it enables a rigorous analysis of the relationship between the change in LMP at any bus with respect to any line error and various physical/economical grid conditions such as the bidding prices for marginal generators and the locations of the congested/erroneous lines. Numerical examples on the impact analysis of this topology error are illustrated in IEEE 14-bus and 118-bus systems.展开更多
An integrated energy system (IES) is a regional energy system incorporating distributed multi-energy systems to serve various energy demands such as electricity, heating, cooling, and gas. The reliability analysis pla...An integrated energy system (IES) is a regional energy system incorporating distributed multi-energy systems to serve various energy demands such as electricity, heating, cooling, and gas. The reliability analysis plays a key role in guaranteeing the safety and adequacy of an IES. This paper aims to build a capacity reliability model of an IES. The multi-energy correlation in the IES can generate the dependent capacity outage states, which is the distinguished reliability feature of an IES from a generation system. To address this issue, this paper presents a novel analytical method to model the dependent multi-energy capacity outage states and their joint outage probabilities of an IES for its reliability assessment. To model the dependent multi-energy capacity outage states, a new multi-dimensional matrix method is presented in the capacity outage probability table (COPT) model of the generation system. Furthermore, a customized multi-dimensional discrete convolution algorithm is proposed to compute the reliability model, and the adequacy indices are calculated in an accurate and efficient way. Case studies demonstrate the correctness and efficiency of the proposed method. The capacity value of multi-energy conversion facilities is also quantified by the proposed method.展开更多
The emerging resistance to schistosoma has been paid much attention and is in urgent need for a novel strategy to control the prevalent parasitic zoonosis. In this study, the efficiency of hyperthermia therapy was inv...The emerging resistance to schistosoma has been paid much attention and is in urgent need for a novel strategy to control the prevalent parasitic zoonosis. In this study, the efficiency of hyperthermia therapy was investigated by the skin hyperthermia device. The survival rate of cercariae decreased from 68.15 %(37 °C, 5 min) to 0(49 °C, 10 min) with the thermal dosages increased, which proved the preventing effect of hyperthermia therapy(P \ 0.05). Therapeutic effects were assessed in Schistosoma japonicum-infected BALB/c mice. When the cercarial contact region of the skin was treated at 45–49 °C for5 min within 8 h of infection, worm reduction rate(WRR)reached 74 %–83 %(P \ 0.01). The sensitivity of adultschistosoma to heat was also investigated using microwave intraperitoneal hyperthermia(thermal dosages 42–43 °C,20 min). The WRR, hepatic shift rates and egg reduction rates were 23.7 %, 40 % and 30 %, respectively, comparing with 80.2 %, 59.6 % and 53.9 % of praziquantel(PZQ)-treated group. Encouraging results have been obtained that hyperthermia can effectively kill schistosomula, especially with the appearance of cercarial dermatitis, while PZQ lacks efficacy against the cercariae. Thus,hyperthermia therapy would show significant benefit in preventing and treatment of schistosoma, especially in the early stage.展开更多
基金the National Natural Science Foundation of China(21978198)for financial support。
文摘In contrast to the concurrent mixer-settler,the interaction between the mixing and settling chambers have to be taken into account in the simulation of the countercurrent mixer-settler,and no work has been reported for this equipment.In this work,a three-phase flow model based on the Eulerian multiphase model,coupled with a sliding mesh model is proposed for a countercurrent mixer-settler.Based on this,the dispersed phase distribution,flow pattern,and pressure distribution are investigated,which can help to fill the gap in the operation mechanism.In addition,the velocity vector distribution at the phase port shows an intriguing phenomenon that two types of vectors with opposite directions are distributed on the left and right sides of the same plane,which indicates that the material exchange in the mixing and settling chambers is simultaneous.Analysis of this variation at this location by a fast Fourier transform(FFT)method reveals that it is mainly influenced by the mixing chamber and is consistent with the main period of the outlet flow fluctuations.Therefore,by monitoring the fluctuation of the outlet flow and then analyzing it by the FFT method,the state of the whole tank can be determined,which makes it promising for the design of control systems for countercurrent mixer-settlers.
基金supported by National Key R&D Program of China(No.2016YFB0900100).
文摘Probabilistic load forecasting(PLF)is able to present the uncertainty information of the future loads.It is the basis of stochastic power system planning and operation.Recent works on PLF mainly focus on how to develop and combine forecasting models,while the feature selection issue has not been thoroughly investigated for PLF.This paper fills the gap by proposing a feature selection method for PLF via sparse L1-norm penalized quantile regression.It can be viewed as an extension from point forecasting-based feature selection to probabilistic forecasting-based feature selection.Since both the number of training samples and the number of features to be selected are very large,the feature selection process is casted as a large-scale convex optimization problem.The alternating direction method of multipliers is applied to solve the problem in an efficient manner.We conduct case studies on the open datasets of ten areas.Numerical results show that the proposed feature selection method can improve the performance of the probabilistic forecasting and outperforms traditional least absolute shrinkage and selection operator method.
基金This work is supported by the National Natural Science Foundation of China(11174207,61138001,61007059,61205094)the Key Scientific and Technological Project of Science and Technology Commission of Shanghai Municipality(11DZ1110800)+2 种基金the Major National Development Project of Scientific Instrument and Equipment(2011YQ150021)National Program on Key Basic Research Project of China(2012CB934203)the Leading Academic Discipline Project of Shanghai Municipal Government(S30502).
文摘The resonant frequencies of the excited surface waves on a metal hole array with respect to the incident angle were studied in the terahertz region.The experimental and theoretical results demonstrate that the resonant peak of surface wave excitation splits into two when transmitted through a metal hole array off-normally.The high-order mode with resonant frequency above the cutoff frequency fc(plasma frequency effect)has a shorter attenuation length than that of the low-order mode whose resonant frequency is below fc.The reason is that the high-order mode is a coupled mode consisting of surface wave and hole modes,while the low-order mode is just an excited surface wave(which can be considered as the spoof surface plasmons).Our investigation may open a door to distinguish the spoof surface plasmons and the coupled modes of surface waves and hole modes.
基金supported by National Natural Science Foundation of China(No.51537005)State Grid Corporation of China ‘‘Research on the model and application of power supply and demand technology under the market trading environment’’
文摘With the deregulation of the electric power industry, electricity price forecasting plays an increasingly important role in electricity markets, especially for retailors and investment decision making. Month ahead average daily electricity price profile forecasting is proposed for the first time in this paper. A hybrid nonlinear regression and support vector machine(SVM) model is proposed. Offpeak hours, peak hours in peak months and peak hours in off-peak months are distinguished and different methods are designed to improve the forecast accuracy. A nonlinear regression model with deviation compensation is proposed to forecast the prices of off-peak hours and peak hours in off-peak months. SVM is adopted to forecast the prices of peak hours in peak months. Case studies based on data from ERCOT validate the effectiveness of the proposed hybrid method.
基金This work was supported in part by NSF CyberSEES-1331863,ECCS-1546682,NSF grants CNS-1149458,AST-1443891,EFRI-1440969,CCF-1331863,IIS-1636772NSF Science&Technology Center Grant CCF-0939370Electric Reliability Council of Texas(ERCOT),and the Power Systems Engineering Research Center.
文摘Demand Response(DR)provides both operational and financial benefits to a variety of stakeholders in the power system.For example,in the deregulated market operated by the Electric Reliability Council of Texas(ERCOT),load serving entities(LSEs)usually purchase electricity from the wholesale market(either in day-ahead or real-time market)and sign fixed retail price contracts with their end-consumers.Therefore,incentivizing end-consumers’load shift from peak to off-peak hours could benefit the LSE in terms of reducing its purchase of electricity under high prices from the real-time market.As the first-of-its-kind implementation of Coupon Incentive-based Demand Response(CIDR),the EnergyCoupon project provides end-consumers with dynamic time-of-use DR event announcements,individualized load reduction targets with EnergyCoupons as the incentive for meeting these targets,as well as periodic lotteries using these coupons as lottery tickets for winning dollar-value gifts.A number of methodologies are developed for this special type of DR program including price/baseline prediction,individualized target setting and a lottery mechanism.This paper summarizes the methodologies,design,critical findings,as well as the potential generalization of such an experiment.Comparison of the EnergyCoupon with a conventional Time-of-Use(TOU)price-based DR program is also conducted.Experimental results in the year 2017 show that by combining dynamic coupon offers with periodic lotteries,the effective cost for demand response providers in EnergyCoupon can be substantially reduced,while achieving a similar level of demand reduction as conventional DR programs.
文摘The pathogenic factors of deafness are complex;more than 50%of cases are caused by genetic factors.Between 75%and 80%of cases of hereditary hearing impairment are autosomal recessive,15%to 25%are autosomal dominant,and 1%to 2%are mitochondrial or X-linked.Cochlea implantation is the main method for treating severe and extremely severe bilateral sensorineural deafness and it is widely used in clinical treatment.As clinical cases of cochlea implantation accumulate,differences in the efficacy of implantation in individuals are emerging and attracting attention.In addition to residual hearing level,implantation age,and other factors,gene mutation is an important factor influencing postoperative rehabilitation in patients.With continuous progress in genetic testing technology for deafness,genetic diagnosis has become an important tool in preoperative evaluation and postoperative effect prediction in patients undergoing cochlear implantation.This article reviews the current status and future development of cochlear implantation in the treatment of hereditary deafness resulting from mutations in common deafness-causing genes.
基金This work was supported by the Science and Technology Project of State Grid Corporation of China(1200-201999526A-0-0-00)National High-End Think Tank Construction Project of National Governance and Global Governance Institute of Tsinghua University(2020WTF044).
文摘As COVID-19 sweeps through the whole world,human activities have been changed significantly.Under such circumstances,the electricity sector is deeply affected and faced with great challenges.This paper provides a comprehensive review of the impacts that the pandemic has caused on the electricity sector.Electricity demand has dropped sharply as governments around the world executed lockdown restrictions,while the load composition and daily load profile have also changed.The share of renewable generation has increased against the decline of the total electricity generation.Changed power balance situation and increased uncertainty of demand have posed higher pressure on system operators,along with voltage violation issue and challenges for system maintenance and management.The electricity market is also substantially influenced,while longterm investment in clean energy is expected to be stable.The externality such as emission reduction is also discussed.
基金supported by the National Science Foundation(No.OAC-1934675,No.ECCS-2035688,No.ECCS-1611301)。
文摘In this study,a machine learning based method is proposed for creating synthetic eventful phasor measurement unit(PMU)data under time-varying load conditions.The proposed method leverages generative adversarial networks to create quasi-steady states for the power system under slowly-varying load conditions and incorporates a framework of neural ordinary differential equations(ODEs)to capture the transient behaviors of the system during voltage oscillation events.A numerical example of a large power grid suggests that this method can create realistic synthetic eventful PMU voltage measurements based on the associated real PMU data without any knowledge of the underlying nonlinear dynamic equations.The results demonstrate that the synthetic voltage measurements have the key characteristics of real system behavior on distinct time scales.
基金supported by the National Key Research and Development Program of China(No.2017YFB0902200)National Natural Science Foundation of China(No.U1766201)State Grid Technology Project(No.SGGSKY00FJJS1600209)。
文摘For the planning,operation and control of multiterminal voltage source converter(VSC)based high-voltage direct current(HVDC)(VSC-MTDC)systems,an accurate power flow formulation is a key starting point.Conventional power flow formulations assume the constant frequencies for all asynchronous AC systems.Therefore,a new feature about the complex coupling relations between AC frequencies,DC voltages and the exchanged power via VSC stations cannot be characterized if VSC-MTDC systems are required to provide cross-regional frequency responses.To address this issue,this paper proposes a comprehensive frequency-dependent power flow formulation.The proposed approach takes the frequencies of asynchronous AC systems as explicit variables,and investigates the novel bus models of the interlinking buses of VSC stations.The proposed approach accommodates different operation modes and frequency droop strategies of VSC stations,and considers the power losses of VSC stations.The effectiveness and generality of the developed approach are validated by a 6-terminal VSC-HVDC test system.The test system presents the characteristics of the coexistence of numerous VSC operation modes,the absence of slack buses in both AC and DC subsystems,and diversified grid configurations such as point-to-point integration of renewable energy sources and one AC system integrated with multiple VSC stations.
基金supported in part by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIP)(No.2015R1C1A1A01051890)part by the National Science Foundation DGE-1303378
文摘This paper examines the impact of power transmission network topology change on locational marginal price(LMP) in real-time power markets. We consider the case where the false status of circuit breakers(CBs) that bypass topology error processing can generate an incorrect power system network topology, subsequently distorting the results of the state estimation and economic dispatch.The main goal of this paper is to assess the economic impact of this misconfigured network topology on realtime LMP in an entire power system with network congestion. To this end, we start with our prior result, a simple and analytical congestion price equation, which can be applied to any single line congestion scenario. This equation can be extended to better understand the degree to which the LMP at any bus changes due to any line status error. Furthermore, it enables a rigorous analysis of the relationship between the change in LMP at any bus with respect to any line error and various physical/economical grid conditions such as the bidding prices for marginal generators and the locations of the congested/erroneous lines. Numerical examples on the impact analysis of this topology error are illustrated in IEEE 14-bus and 118-bus systems.
基金This work was supported in part by the National Natural Science Foundation of China (No. 51637008)the National Key Research and Development Program of China (No. 2016YFB0901900).
文摘An integrated energy system (IES) is a regional energy system incorporating distributed multi-energy systems to serve various energy demands such as electricity, heating, cooling, and gas. The reliability analysis plays a key role in guaranteeing the safety and adequacy of an IES. This paper aims to build a capacity reliability model of an IES. The multi-energy correlation in the IES can generate the dependent capacity outage states, which is the distinguished reliability feature of an IES from a generation system. To address this issue, this paper presents a novel analytical method to model the dependent multi-energy capacity outage states and their joint outage probabilities of an IES for its reliability assessment. To model the dependent multi-energy capacity outage states, a new multi-dimensional matrix method is presented in the capacity outage probability table (COPT) model of the generation system. Furthermore, a customized multi-dimensional discrete convolution algorithm is proposed to compute the reliability model, and the adequacy indices are calculated in an accurate and efficient way. Case studies demonstrate the correctness and efficiency of the proposed method. The capacity value of multi-energy conversion facilities is also quantified by the proposed method.
基金supported by the Bill & Melinda Gates Foundation(Grant No.1024516)
文摘The emerging resistance to schistosoma has been paid much attention and is in urgent need for a novel strategy to control the prevalent parasitic zoonosis. In this study, the efficiency of hyperthermia therapy was investigated by the skin hyperthermia device. The survival rate of cercariae decreased from 68.15 %(37 °C, 5 min) to 0(49 °C, 10 min) with the thermal dosages increased, which proved the preventing effect of hyperthermia therapy(P \ 0.05). Therapeutic effects were assessed in Schistosoma japonicum-infected BALB/c mice. When the cercarial contact region of the skin was treated at 45–49 °C for5 min within 8 h of infection, worm reduction rate(WRR)reached 74 %–83 %(P \ 0.01). The sensitivity of adultschistosoma to heat was also investigated using microwave intraperitoneal hyperthermia(thermal dosages 42–43 °C,20 min). The WRR, hepatic shift rates and egg reduction rates were 23.7 %, 40 % and 30 %, respectively, comparing with 80.2 %, 59.6 % and 53.9 % of praziquantel(PZQ)-treated group. Encouraging results have been obtained that hyperthermia can effectively kill schistosomula, especially with the appearance of cercarial dermatitis, while PZQ lacks efficacy against the cercariae. Thus,hyperthermia therapy would show significant benefit in preventing and treatment of schistosoma, especially in the early stage.