The effects of surface adsorption of bovine serum albumin(BSA) and human gamma-globulin(HGG) on the tribological performance of a DLC film were investigated using a quartz crystal microbalance with dissipation(QCM-D),...The effects of surface adsorption of bovine serum albumin(BSA) and human gamma-globulin(HGG) on the tribological performance of a DLC film were investigated using a quartz crystal microbalance with dissipation(QCM-D), a ball-on-disk reciprocating tribometer, and a three-electrode electrochemical cell. The results showed that the wear depth in the BSA solution was higher than that in the HGG solution. In the HGG solution, the HGG-adsorbed layer could act as a lubricating layer and protect the DLC film from wear. The wear volume of DLC film in BSA and HGG mixture solution was higher than that in single HGG solution. This may be because the BSA molecules inhibit the formation of HGG adsorbed layer during sliding.展开更多
A TioO2-x/TiN multilayer film was synthesized by ion beam enhanced deposition to modify the properties of material for artificial heart valve (AHV). The blood compatibility of the film was evaluated by clotting time m...A TioO2-x/TiN multilayer film was synthesized by ion beam enhanced deposition to modify the properties of material for artificial heart valve (AHV). The blood compatibility of the film was evaluated by clotting time measurement, platelet adhesion test, hemolysis analysis and protein adsorption experiment. The investigation on mechanical properties including fatigue life, wear resistance and adhesion strength between AHV material matrix and the film were carried out. the results revealed a significant improvement of blood compatibility of AHV material by the film coating, and the high level of mechanical properties have also been demonstrated. The synthesized film shows a promising of more desirable AHV material.展开更多
基金Funded by the National Natural Science Foundation of China(No.31570958)Science and Technology Support Program of Sichuan Province(No.2016SZ0007)
文摘The effects of surface adsorption of bovine serum albumin(BSA) and human gamma-globulin(HGG) on the tribological performance of a DLC film were investigated using a quartz crystal microbalance with dissipation(QCM-D), a ball-on-disk reciprocating tribometer, and a three-electrode electrochemical cell. The results showed that the wear depth in the BSA solution was higher than that in the HGG solution. In the HGG solution, the HGG-adsorbed layer could act as a lubricating layer and protect the DLC film from wear. The wear volume of DLC film in BSA and HGG mixture solution was higher than that in single HGG solution. This may be because the BSA molecules inhibit the formation of HGG adsorbed layer during sliding.
文摘A TioO2-x/TiN multilayer film was synthesized by ion beam enhanced deposition to modify the properties of material for artificial heart valve (AHV). The blood compatibility of the film was evaluated by clotting time measurement, platelet adhesion test, hemolysis analysis and protein adsorption experiment. The investigation on mechanical properties including fatigue life, wear resistance and adhesion strength between AHV material matrix and the film were carried out. the results revealed a significant improvement of blood compatibility of AHV material by the film coating, and the high level of mechanical properties have also been demonstrated. The synthesized film shows a promising of more desirable AHV material.
