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血浆β2微球蛋白水平与老年轻度认知障碍的关系研究 被引量:6
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作者 李捷思 潘梓末 +1 位作者 陈陵霞 王晶桐 《中国全科医学》 CAS 北大核心 2021年第30期3878-3881,共4页
背景随着我国进入老龄化社会,老年轻度认知障碍(MCI)越来越常见,β2微球蛋白(β2M)作为一种新的生物标志物逐渐进入大众视野,而β2M在衰老和认知调节中的作用尚存在很大争议。目的探究血浆β2M水平与老年MCI的关系。方法选取2018年6月至... 背景随着我国进入老龄化社会,老年轻度认知障碍(MCI)越来越常见,β2微球蛋白(β2M)作为一种新的生物标志物逐渐进入大众视野,而β2M在衰老和认知调节中的作用尚存在很大争议。目的探究血浆β2M水平与老年MCI的关系。方法选取2018年6月至2019年6月在北京大学人民医院老年科住院的233例患者为研究对象。依据蒙特利尔认知评估量表(MoCA)评分将所有患者分为MCI组108例,认知正常(NC)组125例。收集两组患者人口学特征及入院时实验室检查指标。比较两组患者人口学特征、实验室检查指标、MoCA评分,分析MoCA评分与年龄、受教育年限、血浆β2M水平的相关性。采用二元Logistic回归分析探究老年患者发生MCI影响因素。结果MCI组患者年龄、血浆β2M水平高于NC组,受教育年限少于NC组,MoCA评分低于NC组(P<0.05)。Spearman秩相关分析结果显示,年龄(rs=-0.361,P<0.001)、血浆β2M水平(rs=-0.283,P<0.001)与MoCA评分呈负相关,受教育年限与MoCA评分呈正相关(rs=0.305,P<0.001)。控制年龄为协变量,二元Logistic回归分析结果显示,血浆β2M水平〔OR=1.955,95%CI(1.060,3.606)〕是老年患者发生MCI的危险因素,受教育年限〔OR=0.860,95%CI(0.777,0.951)〕是老年患者发生MCI的保护因素(P<0.05)。结论血浆β2M水平是老年患者发生MCI的独立危险因素,对血浆β2M水平较高的老年人进行筛查有助于早期识别MCI及预防MCI的发生发展。 展开更多
关键词 认知障碍 老年人 Β2微球蛋白 影响因素分析
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老年人体质量指数与轻度认知功能障碍的关系 被引量:4
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作者 赵晨昭 李娇娇 +2 位作者 张茗 李捷思 陈陵霞 《中华老年心脑血管病杂志》 CAS 北大核心 2019年第10期1058-1062,共5页
目的探讨老年人体质量指数(BMI)与轻度认知功能障碍(MCI)的关系。方法选择2016年10月~2018年6月北京大学人民医院老年科住院的老年患者648例,根据MCI诊断标准分为MCI组216例,对照组432例。收集既往病史资料,计算BMI,其中低体质量45例,... 目的探讨老年人体质量指数(BMI)与轻度认知功能障碍(MCI)的关系。方法选择2016年10月~2018年6月北京大学人民医院老年科住院的老年患者648例,根据MCI诊断标准分为MCI组216例,对照组432例。收集既往病史资料,计算BMI,其中低体质量45例,正常体质量279例,超重244例,肥胖80例,分析BMI与MCI的关系。结果 MCI组年龄、慢性肾功能不全、糖尿病病程、尿素、尿微量白蛋白/肌酐较对照组明显升高,BMI、蒙特利尔认知评估量表评分、受教育年限、白蛋白、估算肾小球滤过率较对照组明显降低,差异有统计学意义(P<0.05,P<0.01)。与正常体质量比较,低体质量患者MoCA评分明显降低,MCI患病率明显升高,超重和肥胖患者MoCA评分明显升高,MCI患病率明显降低,差异有统计学意义(P<0.05)。低体质量、正常体质量、超重和肥胖患者MCI患病率分别为62.2%、41.6%、24.2%、16.3%,差异有统计学意义(P<0.01)。logistic回归分析显示,与正常体质量比较,超重患者发生MCI的风险降低(OR=0.413,95%CI:0.200~0.851,P=0.016)。结论在一定范围内BMI可能为老年人MCI发生的保护因素。 展开更多
关键词 人体质量指数 认知障碍 肾小球滤过率 糖尿病 肥胖症
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维奈克拉联合减低剂量HAD方案诱导治疗急性髓系白血病的疗效观察
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作者 阎嶂松 李洋 +7 位作者 张斌 贺劲松 李捷思 魏述宁 王齐 李秋玲 刘凯奇 秘营昌 《中华血液学杂志》 CAS CSCD 北大核心 2024年第4期387-390,共4页
通过回顾性分析自2022年5月至2023年1月收治的25例初诊急性髓系白血病(AML)患者,探索应用维奈克拉联合减低剂量HAD(高三尖杉酯碱+柔红霉素+阿糖胞苷)方案诱导治疗初诊AML的疗效及安全性。按照ELN 2017预后分层标准,低危组13例(52.0%),... 通过回顾性分析自2022年5月至2023年1月收治的25例初诊急性髓系白血病(AML)患者,探索应用维奈克拉联合减低剂量HAD(高三尖杉酯碱+柔红霉素+阿糖胞苷)方案诱导治疗初诊AML的疗效及安全性。按照ELN 2017预后分层标准,低危组13例(52.0%),中危组3例(12.0%),高危组9例(36.0%)。1个疗程诱导治疗总体有效率(完全缓解率+部分缓解率)88.0%,1个疗程完全缓解率84.0%。截至2023年5月30日,中位随访9个月,全部患者诱导治疗后给予巩固治疗2(1~5)个周期。1年总生存率、无事件生存率、无复发生存率分别为100%、94.7%、94.7%。维奈克拉联合减低剂量HAD诱导方案,1个疗程完全缓解率高,安全性良好。 展开更多
关键词 急性髓系白血病 诱导治疗 完全缓解率 巩固治疗 诱导方案 减低剂量 疗效及安全性 高三尖杉酯碱
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王晨在“百名法学家百场报告会”组委会会议上强调 深入开展法治宣传教育 弘扬社会主义法治精神
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作者 li jiesi 《China Legal Science》 2023年第4期159-160,共2页
Wang Chen, president of the China Law Society, attended the organizing committee conference of ‘100 Lectures of 100 Jurists’ of 2023 on the publicity of the rule of law on June 29. He stressed that we should follow ... Wang Chen, president of the China Law Society, attended the organizing committee conference of ‘100 Lectures of 100 Jurists’ of 2023 on the publicity of the rule of law on June 29. He stressed that we should follow the guidance of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era, thoroughly implement the guiding principles of the 20th CPC National Congress, carry out intensive activities to raise public awareness of the rule of law, promote the socialist rule of law. 展开更多
关键词 王晨 LAW CARRY
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THE RETRIAL OF THE NIE SHUBIN CASE: THE ORIGIN, PROBLEMS AND SIGNIFICANCE
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作者 胡云腾 赖早兴 li jiesi 《China Legal Science》 2017年第5期128-157,共30页
On December 2,2016,the Second Circuit Court of the Supreme People’s Court proclaimed the judgment of the Nie Shubin case for intentional homicide and rape in public,revoking the conviction judgment of the defendant N... On December 2,2016,the Second Circuit Court of the Supreme People’s Court proclaimed the judgment of the Nie Shubin case for intentional homicide and rape in public,revoking the conviction judgment of the defendant Nie Shubin rendered by the Intermediate People’s Court of Shi Jiazhuang City in Hebei Province in 1994 and the High People’s Court of Hebei Province in 1995 and acquitted Nie Shubin.So far,this momentous,difficult and complicated case,which occurred,tried and implemented 展开更多
关键词 judgment instance COURT JUDICIAL Hebei INTENTIONAL 聂树斌 crime justice Intermediate
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我国公用事业特许经营的立法现状及司法适用
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作者 关博豪 li jiesi 《China Legal Science》 2022年第5期54-79,共26页
特许经营协议是我国基础设施和公用事业运营的合作协议,对该领域服务外包的良性发展起着重要作用。在某些特殊情况下,有关行政部门有权撤销特许经营协议,并收回特许经营权。寿光中石油昆仑燃气有限公司诉寿光市人民政府、潍坊市人民政... 特许经营协议是我国基础设施和公用事业运营的合作协议,对该领域服务外包的良性发展起着重要作用。在某些特殊情况下,有关行政部门有权撤销特许经营协议,并收回特许经营权。寿光中石油昆仑燃气有限公司诉寿光市人民政府、潍坊市人民政府解除政府特许经营协议案作为最高人民法院关于行政协议的公报案例,确立了此类案件判决的规则。首先,明确了行政部门撤销特许经营协议需要符合法定条件并遵循法定程序;其次,出于维护社会公共利益的考量,未经法定程序撤销特许经营协议的行政行为仍然有效,但应给予特许经营方适当的补偿。该判决兼顾了社会公共利益和特许经营方的权益,为特许经营协议的纠纷解决提供了合理的路径。 展开更多
关键词 法定条件 立法现状 特许经营协议 司法适用 纠纷解决 社会公共利益 基础设施 特许经营权
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中国法学会法学期刊研究会2019年年会会议综述(英文)
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作者 li jiesi 《China Legal Science》 2019年第5期159-160,共2页
On August 20, 2019, the Annual Conference of Legal Periodicals Association of China Law Society was held in Kunming. It was hosted by the Legal Periodicals Association of China Law Society, organized by the Law School... On August 20, 2019, the Annual Conference of Legal Periodicals Association of China Law Society was held in Kunming. It was hosted by the Legal Periodicals Association of China Law Society, organized by the Law School of Yunnan University and co-organized by China National Knowledge Infrastructure (CNKI) and Kunming Yunwen Education Information Consulting Co., Ltd. The theme of the conference is Serve Comprehensively Implementing the Rule of Law and Lead Legal Research: The Mission of Legal Periodicals in the New Era. More than 200 people attended the conference, including members, directors of the Legal Periodicals Association of China Law Society and related experts and scholars, editors and representatives from data companies. 展开更多
关键词 中国法学会 期刊研究 综述 年会 the LAW MORE THAN
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2018年全国刑法学术年会综述(英文)
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作者 li jiesi 《China Legal Science》 2019年第2期159-160,共2页
On December 16,the National Annual Academic Conference of the Criminal Law was held in Nanning. Wang Lequan. President of the China Law Society attended the opening ceremony and delivered an important speech. Huang Sh... On December 16,the National Annual Academic Conference of the Criminal Law was held in Nanning. Wang Lequan. President of the China Law Society attended the opening ceremony and delivered an important speech. Huang Shiyong. Member of the Standing Committee of Guangxi Zhuang Autonomous Regional Committee of the Communist Party of China (CPC) and Secretary of the Political and Legal Committee, attended and made a speech. Zhang Wenxian, Member of the Party Group, Vice President and Director of the Academic Committee of China Law Society. Zhu Xiaoqing. former Deputy Chief Prosecutor of the Supreme People s Procuratorate, Lcmg Sheng, former Deputy Director of the Law Committee of the National People s Congress, Huang Hailong, President of the High People s Court of Guangxi Zhuang Autonomous Region, Jia Yu. Chief Prosecutor of Zhejiang Provincial People s Procuratorate, Wen Kahua. President of the Law Society of Guangxi Zhuang Autonomous Region, Zhao Yueyu, Principal of Guangxi University, Professor Zhao Bingzhi. President of China Criminal Law Research Institute attended the conference. The opening ceremony was presided over by Prof. Chen Zexian. Executive Vice President of the China Criminal Law Research Institute. 展开更多
关键词 NATIONAL ANNUAL ACADEMIC CONFERENCE CRIMINAL LAW
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王晨在中国法学会会长会议上强调 法学法律工作者要深入学习贯彻落实党的二十大精神 为在法治轨道上全面建设社会主义现代化国家贡献力量
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作者 li jiesi 《China Legal Science》 2022年第6期159-160,共2页
Wang Chen, vice chairman of the Standing Committee of the National People’s Congress and president of the China Law Society, stressed when presiding over the presidents’ conference of China Law Society on October 26... Wang Chen, vice chairman of the Standing Committee of the National People’s Congress and president of the China Law Society, stressed when presiding over the presidents’ conference of China Law Society on October 26 that law professionals should fully study and implement the guiding principles of the 20th National Congress of the Communist Party of China(CPC)。 展开更多
关键词 法律工作者 中国法学会 会长会议 法治轨道
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REVIEW OF THE FORUM ON THE BELT AND ROAD LEGAL COOPERATION
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作者 li jiesi 《China Legal Science》 2018年第5期159-160,共2页
On July 2, the Forum on the Belt and Road Legal Cooperation was held in Beijing. Wang Yi, State Councilor and Foreign Minister, attended the opening ceremony and delivered a keynote speech. Wang Lequan, President of t... On July 2, the Forum on the Belt and Road Legal Cooperation was held in Beijing. Wang Yi, State Councilor and Foreign Minister, attended the opening ceremony and delivered a keynote speech. Wang Lequan, President of the China Law Society, attended and made special remarks.Wang Yi stated that since President Xi Jinping proposed the Belt and Road Initiative five year ago, fruitful cooperation outcomes have 展开更多
关键词 一带一路 中国 法律解释 司法工作
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REVIEW OF THE THREE MAJOR JOURNALS+ AUTHOR- READER. EDITOR MEETING IN 2017
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作者 li jiesi 《China Legal Science》 2018年第1期157-160,共4页
On November 11,2017,the Three Major Journals+Author·Reader·Editor Meeting in 2017 was held at the Donghu Hotel in Wuhan,which promoted legal journals to lead and serve the research on the socialist rule of l... On November 11,2017,the Three Major Journals+Author·Reader·Editor Meeting in 2017 was held at the Donghu Hotel in Wuhan,which promoted legal journals to lead and serve the research on the socialist rule of law with Chinese characteristics.It was sponsored by Social Sciences in China Press,Chinese Journal of Law Press and China Legal 展开更多
关键词 中国特色社会主义 法律出版社 期刊 发展现状
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REVIEW ON THE CHINA RULE OF LAW FORUM IN 2018
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作者 li jiesi 《China Legal Science》 2018年第4期159-160,共2页
On May 7,2018,the China Rule of Law Forum was held in Shenzhen,Guangdong Province.The forum was jointly sponsored by the China Law Society,the CPC Shenzhen Municipal Committee and Government,and the Law Society of Gua... On May 7,2018,the China Rule of Law Forum was held in Shenzhen,Guangdong Province.The forum was jointly sponsored by the China Law Society,the CPC Shenzhen Municipal Committee and Government,and the Law Society of Guangdong Province.Wang Lequan,President of the China 展开更多
关键词 中国法治论坛 广东 发展现状 司法建设
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中国法学会宪法学研究会2021年年会综述
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作者 li jiesi 《China Legal Science》 2022年第2期159-160,共2页
On October 23-24, 2021, the annual conference and general meeting of the Constitutional Law Research Association of China Law Society was successfully held in Shenzhen, Guangdong. The annual conference was co-hosted b... On October 23-24, 2021, the annual conference and general meeting of the Constitutional Law Research Association of China Law Society was successfully held in Shenzhen, Guangdong. The annual conference was co-hosted by the Constitutional Law Research Association of China Law Society, the Law School of Shenzhen University, and the Center for Basic Laws of Hong Kong and Macao Special Administrative Region of Shenzhen University with the theme of The Communist Party of China and the Constitutional Path of Socialism with Chinese Characteristics. 展开更多
关键词 中国法学会 Basic 年会综述
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深入学习研究阐释习近平法治思想研讨会综述
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作者 li jiesi 《China Legal Science》 2022年第4期158-160,共3页
On June 14,Wang Chen,a member of the Political Bureau of the Communist Party of China Central Committee,vice chairman of the Standing Committee of the National People’s Congress,and president of the China Law Society... On June 14,Wang Chen,a member of the Political Bureau of the Communist Party of China Central Committee,vice chairman of the Standing Committee of the National People’s Congress,and president of the China Law Society,attended the seminar on thorough study and interpretation of Xi Jinping Thought on the Rule of Law in Beijing and delivered a speech.He emphasized that we should thoroughly study the original contribution of Xi Jinping Thought on the Rule of Law. 展开更多
关键词 thoroughly 习近平法治思想 COMMUNIST
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2021年“双百”活动中央和国家机关专场报告会综述
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作者 li jiesi 《China Legal Science》 2021年第4期159-160,共2页
On June 7, 2021, the‘One Hundred Reports of One Hundred Jurists’, an activity to publicize the rule of law, was held at the China Law Society.Chen Xunqiu, Secretary of the Leading Party Group and Executive Vice Pres... On June 7, 2021, the‘One Hundred Reports of One Hundred Jurists’, an activity to publicize the rule of law, was held at the China Law Society.Chen Xunqiu, Secretary of the Leading Party Group and Executive Vice President of China Law Society, and Executive Vice Director of the Organizing Committee of ‘One Hundred Reports of One Hundred Jurists’. 展开更多
关键词 DIRECTOR LAW SECRETARY
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第七届南海法律高端论坛会议综述(英文)
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作者 Gong li li jiesi 《China Legal Science》 2020年第1期156-160,共5页
From December 21 to 23,2019,the Seventh South China Sea High-end Forum was held in Haikou,Hainan Province.The forum was co-sponsored by the Legal Periodicals Association of the China Law Society and Hainan University,... From December 21 to 23,2019,the Seventh South China Sea High-end Forum was held in Haikou,Hainan Province.The forum was co-sponsored by the Legal Periodicals Association of the China Law Society and Hainan University,and hosted by the Law School of Hainan University,Haikou Maritime Court,and the Research Center for Policy and Law of the South China Sea of Hainan Province.Guided by General Secretary Xi Jinping's series of important speeches and discussions on governing the ocean,experts and scholars at the meeting made speeches and exchanged views on relevant theoretical and practical issues of building the community of marine destiny. 展开更多
关键词 Province. HAINAN OCEAN
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中国刑事诉讼法学研究会2019年年会综述
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作者 Gong li li jiesi 《China Legal Science》 2020年第3期159-160,共2页
From November 16 to 17,2019,the annual conference and membership congress of the China Criminal Procedure Law Research Institute was successfully held in Guangzhou.The annual conference was hosted by the China Crimina... From November 16 to 17,2019,the annual conference and membership congress of the China Criminal Procedure Law Research Institute was successfully held in Guangzhou.The annual conference was hosted by the China Criminal Procedure Law Research Institute,co-organized by Guangdong University of Foreign Studies Law School and Institute of Rule of Law.This year marks the 40th anniversary of the enactment of China’s Criminal Procedure Law.The theme of this annual meeting is‘Construction of the Rule of Law and Criminal Procedure:40 Years of the Criminal Procedure Law’.Wang Qijiang,PartyMember and Vice President of China Law Society,Gao Jinghong,Vice President of the Supreme People’s Court,Chen Guoqing,Deputy Procurator-General of the Supreme People’s Procuratorate,Chen Guangzhong,Honorary President of the China Criminal Procedure Law Research Institute,Bian Jianlin,President of the China Criminal Procedure Law Research Institute,Liang Weifa,President of China Law Society of Guangdong Province,Shi Youqi,President of Guangdong University of Foreign Studies,and other heads attended the conference.More than 350 representatives in the legal field from the Legislative Affairs Commission of the Standing Committee of the National People’s Congress,the Supervisory and Judicial Affairs Committee of the Standing Committee of the National People’s Congress,the Supreme People’s Court,the Supreme People’s Procuratorate,political and legal system of Guangdong Province,China University of Political Science and Law,Renmin University of China,Peking University and other institutions attended the conference. 展开更多
关键词 LEGAL MEMBERSHIP GUANGDONG
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中国国际法学会2019年学术年会综述(英文)
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作者 li jiesi 《China Legal Science》 2019年第4期159-160,共2页
On the morning of May 18, 2019, the Annual Academic Conference of Chinese Society of International Law, co- sponsored by the Chinese Society of International Law and Northwest University of Political Science and Law, ... On the morning of May 18, 2019, the Annual Academic Conference of Chinese Society of International Law, co- sponsored by the Chinese Society of International Law and Northwest University of Political Science and Law, was held in Xi'an. The theme of the annual conference is Development of the International Law in the Past 70 Years of New China: Challenges and Countermeasures to Multilateralism. Huang Jin, President of the Chinese Society of International Law, and Yang Zongke, Principal of Northwest University of Political Science and Law, delivered speeches at the opening ceremony respectively. Luo Dongchuan, Vice President of the Supreme People's Court, attended the opening ceremony and delivered a speech. Fan Yongbin, Deputy Director General of the Education Department of Shaanxi Province, made a speech. Li Ming, Executive Vice President of the Chinese Society of International Law, presided over the opening ceremony. 展开更多
关键词 中国国际法学会 学术 年会
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CONFERENCE REVIEW OF CHINA LEGAL SCIENCE EDITORIAL BOARD IN 2017
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作者 li jiesi 《China Legal Science》 2018年第3期159-160,共2页
The editorial board of China Legal Science recently held its annual conference of 2017 at the Ritan Hotel in Beijing.Professor Zhang Wenxian,Vice President of the China Law Society and Director of the editorial board ... The editorial board of China Legal Science recently held its annual conference of 2017 at the Ritan Hotel in Beijing.Professor Zhang Wenxian,Vice President of the China Law Society and Director of the editorial board of China Legal Science hosted the conference.More than 20 editorial board members and all editors of China Legal Science attended the conference. 展开更多
关键词 中国 法制建设
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ANNUAL CONFERENCE REVIEW OF THE CHINA CIVIL PROCEDURE LAW RESEARCH INSTITUTE IN 2016
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作者 li jiesi 《China Legal Science》 2017年第5期158-160,共3页
The Annual Conference of the China Civil Procedure Law Research Institute in 2016 was held in the Qujiang International Conference Center of Xi’an City on November 12 and 13,2016.It was jointly sponsored by the China... The Annual Conference of the China Civil Procedure Law Research Institute in 2016 was held in the Qujiang International Conference Center of Xi’an City on November 12 and 13,2016.It was jointly sponsored by the China Civil Procedure Law Research Institute,Northwest University of Political Science and Law,and the High People’s Court of Shaanxi Province.On the morning of November 12,the opening ceremony of the 展开更多
关键词 LI
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