Two new benzofuran lignan glycosides, gelsemiunoside A and B, were isolated from the whole plant of Gelsemium elegans Benth. Their structures were elucidated on the basis of spectroscopic evidence. Furthermore, gelsem...Two new benzofuran lignan glycosides, gelsemiunoside A and B, were isolated from the whole plant of Gelsemium elegans Benth. Their structures were elucidated on the basis of spectroscopic evidence. Furthermore, gelsemiunoside A and B were shown a potent cytotoxic activity by suppressing the proliferation of A375-S2 cells.展开更多
A new alkaloid, named 6-（2＇,3＇-dihydroxy-4＇-hydroxymethyl-tetrahydro-furan-1＇-yl）cyclopentadiene[c]pyrrole-1,3-diol, was isolated from the seeds of Castanea mollissima Blume. The structure was elucidated based o...A new alkaloid, named 6-（2＇,3＇-dihydroxy-4＇-hydroxymethyl-tetrahydro-furan-1＇-yl）cyclopentadiene[c]pyrrole-1,3-diol, was isolated from the seeds of Castanea mollissima Blume. The structure was elucidated based on spectroscopic evidence including 2D NMR techniques.展开更多
Two new acetylated ginsenosides, 20（S）-protopanaxatriol-6-O-α-L-rhamnopyranosyl （1 → 2）-β-D-6＇-O-acetylglucopyranoside （1） and 20（R）-protopanaxatrol-6-O-α-L-rhamnopyranosyl （1 → 2）-β-o-6＇-O-acetylglu...Two new acetylated ginsenosides, 20（S）-protopanaxatriol-6-O-α-L-rhamnopyranosyl （1 → 2）-β-D-6＇-O-acetylglucopyranoside （1） and 20（R）-protopanaxatrol-6-O-α-L-rhamnopyranosyl （1 → 2）-β-o-6＇-O-acetylglucopyranoside （2）, were isolated from the roots of Panax quinquefolium. The structures were elucidated on the basis of spectroscopic techniques and chemical means.展开更多
Magnoline（1）,a new isoquinoline derivative,was isolated from the leaves of Magnolia sieboldii K.Koch（Magnoliaceae）.Its structure was elucidated on the basis of spectral analysis including 1D,2D NMR and HR-TOF-MS.
The continuous chemical investigation on the ethyl acetate （EtOAc） soluble fraction of the MeOH extract afforded two new lanostane triterpenoid derivatives including one with a rearranged lanostane skeleton. They we...The continuous chemical investigation on the ethyl acetate （EtOAc） soluble fraction of the MeOH extract afforded two new lanostane triterpenoid derivatives including one with a rearranged lanostane skeleton. They were identified as 3,4-seco-8-（14→13R）abeo-17,13-friedo-9β-lanosta-4（28）, 7,14（30）,24-tetraen-26,23-olide-23-hydroxy-3-oic acid （1） and 7,14-mariesa- dien-3oL-hydroxy-25-methoxy-26-oic acid （2）. Structural determination of these compounds were carried out by the spectral studies especially by the two digital （2D）-NMR and high-resolution MS experiences.展开更多
Chemical investigation of Syringa velutina Kom. led to the isolation of two new secoiridoid glucosides. Their structures were identified as 6＇-O-（6, 7-dihyrofoliamenthoyl）-8-epi-longisidic acid （syrveoside A, 1） ...Chemical investigation of Syringa velutina Kom. led to the isolation of two new secoiridoid glucosides. Their structures were identified as 6＇-O-（6, 7-dihyrofoliamenthoyl）-8-epi-longisidic acid （syrveoside A, 1） and 6＇-O-menthiafoloyl-8-epi-ldngisidic acid （syrveoside B, 2） on the basis of chemical and physicochemical evidence.展开更多
A new compound, 3,6,20（S）-trihydroxy- 12,23-epoxydammar-24-ene,6,20-di-O-β-D-glucopyranoside （1）, was isolated from the leaves of Panax ginseng C.A. Meyer, whose structural elucidation was carried out by means of...A new compound, 3,6,20（S）-trihydroxy- 12,23-epoxydammar-24-ene,6,20-di-O-β-D-glucopyranoside （1）, was isolated from the leaves of Panax ginseng C.A. Meyer, whose structural elucidation was carried out by means of spectral analysis （including IR, HR- FAB-MS and NMR）. This compound showed the moderate cytotoxic activities against U937 and HeLa cells by using the MTT method.展开更多
A new sesquiterpene was isolated from transformation of curdione by cell suspension culture of Platycodon grandiflorum. The structure of the new compound was elucidated on the basis of spectral methods including 2D NMR.
Three compounds were isolated from the tissue culture cells of Daphne giraldii cullus, their structures were identified as daphneolone （1）, S-（＋）-1-（4-hydroxy-3-methoxyphenyl）-3-hydroxy-5-phenyl-l-pentanone （2...Three compounds were isolated from the tissue culture cells of Daphne giraldii cullus, their structures were identified as daphneolone （1）, S-（＋）-1-（4-hydroxy-3-methoxyphenyl）-3-hydroxy-5-phenyl-l-pentanone （2）, S-（＋）-1-（4-methoxyphenyl）-3- hydroxy-5-phenyl-l-pentanone （3）, and among them, 2 was a new compound, 3 was a novel natural product.展开更多
a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside o...a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside on the basis of spectral analysis and chemical evidence.展开更多
The determination of enantiomeric composition by partial least squares （PLS） modeling of UV-vis spectral data was investigated for samples of phenylalanine （phe） using sucrose as a chiral auxiliary. And a new data...The determination of enantiomeric composition by partial least squares （PLS） modeling of UV-vis spectral data was investigated for samples of phenylalanine （phe） using sucrose as a chiral auxiliary. And a new data preprocess method, reference band normalization, was introduced to eliminate the spectral variations due to the changes of total concentration of phe. The determination coefficient （R2） and the standard error of calibration set （SEC） of 13 standard samples are 0.9987 and 0.0128 respectively. The standard error of validation set （SECV） of 7 validation samples is 0.0049. The standard error of predict （SEP） of 6 blind samples for evaluating the robustness of the model is 0.0366. The regression model is robust to determine enantiomeric composition when total concentration varied. It is demonstrated that the reference band normalization is a convenient method of compensating for variations in total concentrations without knowing that in advance.展开更多
基金sponsored by the Scientific Research Foundation for the doctoral Scholars (Q.C.Zhao,No.20031040),Liaoning,China.
文摘Two new benzofuran lignan glycosides, gelsemiunoside A and B, were isolated from the whole plant of Gelsemium elegans Benth. Their structures were elucidated on the basis of spectroscopic evidence. Furthermore, gelsemiunoside A and B were shown a potent cytotoxic activity by suppressing the proliferation of A375-S2 cells.
文摘A new alkaloid, named 6-（2＇,3＇-dihydroxy-4＇-hydroxymethyl-tetrahydro-furan-1＇-yl）cyclopentadiene[c]pyrrole-1,3-diol, was isolated from the seeds of Castanea mollissima Blume. The structure was elucidated based on spectroscopic evidence including 2D NMR techniques.
基金the National Basic Research Program of China(No.2005CB523301).
文摘Two new acetylated ginsenosides, 20（S）-protopanaxatriol-6-O-α-L-rhamnopyranosyl （1 → 2）-β-D-6＇-O-acetylglucopyranoside （1） and 20（R）-protopanaxatrol-6-O-α-L-rhamnopyranosyl （1 → 2）-β-o-6＇-O-acetylglucopyranoside （2）, were isolated from the roots of Panax quinquefolium. The structures were elucidated on the basis of spectroscopic techniques and chemical means.
文摘Magnoline（1）,a new isoquinoline derivative,was isolated from the leaves of Magnolia sieboldii K.Koch（Magnoliaceae）.Its structure was elucidated on the basis of spectral analysis including 1D,2D NMR and HR-TOF-MS.
文摘The continuous chemical investigation on the ethyl acetate （EtOAc） soluble fraction of the MeOH extract afforded two new lanostane triterpenoid derivatives including one with a rearranged lanostane skeleton. They were identified as 3,4-seco-8-（14→13R）abeo-17,13-friedo-9β-lanosta-4（28）, 7,14（30）,24-tetraen-26,23-olide-23-hydroxy-3-oic acid （1） and 7,14-mariesa- dien-3oL-hydroxy-25-methoxy-26-oic acid （2）. Structural determination of these compounds were carried out by the spectral studies especially by the two digital （2D）-NMR and high-resolution MS experiences.
基金supported by the National Key Project of Scientific and Technical Supporting Programs fundedby Ministry of Science & Technology of China(No.2006BAD31B05)
文摘Chemical investigation of Syringa velutina Kom. led to the isolation of two new secoiridoid glucosides. Their structures were identified as 6＇-O-（6, 7-dihyrofoliamenthoyl）-8-epi-longisidic acid （syrveoside A, 1） and 6＇-O-menthiafoloyl-8-epi-ldngisidic acid （syrveoside B, 2） on the basis of chemical and physicochemical evidence.
文摘A new compound, 3,6,20（S）-trihydroxy- 12,23-epoxydammar-24-ene,6,20-di-O-β-D-glucopyranoside （1）, was isolated from the leaves of Panax ginseng C.A. Meyer, whose structural elucidation was carried out by means of spectral analysis （including IR, HR- FAB-MS and NMR）. This compound showed the moderate cytotoxic activities against U937 and HeLa cells by using the MTT method.
基金the National Outstanding Youth Foundation by NNSF of China(39925040)Trans-Century Training Program Foundation for the Talents by the Ministry of Education for financial support
文摘A new sesquiterpene was isolated from transformation of curdione by cell suspension culture of Platycodon grandiflorum. The structure of the new compound was elucidated on the basis of spectral methods including 2D NMR.
文摘Three compounds were isolated from the tissue culture cells of Daphne giraldii cullus, their structures were identified as daphneolone （1）, S-（＋）-1-（4-hydroxy-3-methoxyphenyl）-3-hydroxy-5-phenyl-l-pentanone （2）, S-（＋）-1-（4-methoxyphenyl）-3- hydroxy-5-phenyl-l-pentanone （3）, and among them, 2 was a new compound, 3 was a novel natural product.
文摘a new triterpene compound was isolated from the stems and leaves of Panax ginseng C. A. Meyer and established as 3β, 6α, 12β-trihydroxy-dammar-20(21), 24-diene-6-0-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside on the basis of spectral analysis and chemical evidence.
基金supported by the Near-infrared spectra data in the application of evaluating tobacco leaf quality (No.2010YN65)
文摘The determination of enantiomeric composition by partial least squares （PLS） modeling of UV-vis spectral data was investigated for samples of phenylalanine （phe） using sucrose as a chiral auxiliary. And a new data preprocess method, reference band normalization, was introduced to eliminate the spectral variations due to the changes of total concentration of phe. The determination coefficient （R2） and the standard error of calibration set （SEC） of 13 standard samples are 0.9987 and 0.0128 respectively. The standard error of validation set （SECV） of 7 validation samples is 0.0049. The standard error of predict （SEP） of 6 blind samples for evaluating the robustness of the model is 0.0366. The regression model is robust to determine enantiomeric composition when total concentration varied. It is demonstrated that the reference band normalization is a convenient method of compensating for variations in total concentrations without knowing that in advance.
