Purpose To evaluate the clinical out come and quantify histologically the amount of microscopic internal limiting membrane(ILM)and epiretinal membrane(ERM)pre-sent in ILM and ERM specimens obtained from ERM surgery.De...Purpose To evaluate the clinical out come and quantify histologically the amount of microscopic internal limiting membrane(ILM)and epiretinal membrane(ERM)pre-sent in ILM and ERM specimens obtained from ERM surgery.Design Interventional con secutive case series.Methods Patients scheduled for ERM s urgery were re-cruited prospectively.Pars plana v itrectomy,removal of ERM,and ILM peeling with indocyanin e green(ICG)staining were performed in all patie nts.Epiretinal mem-brane and ILM specimens were sent for histologic exam-ination.The amount of ERM present in ILM specimens and the amount of ILM present in ERM sp ecimens were quantified by manual counting.Outc ome measures in-clude change in best corrected visual acuity(BCVA),proportion of cases with 2or more lin es of visual im-provement,anatomic outcome,proportions of microscopic ERM within ILM,and microscopic ILM w ithin ERM.Results Eighteen eyes in 18patients were operated with a mean follow-up of 19.3months.There were 13primary ERMs and five secondary ERMs.The mea n logMAR BC-VA improved from 0.83preoperatively to 0.49postop-eratively(P<0.001).The mean lines of improvement in BCVA was 3.3lines with 14patients(77.8%)who had 2or more lines of BCVA improvemen t.Histologic e-valuation of the specimens showed no significant correla-tion with the final BCVA of 20/50or better.Eleven(61.1%)of the ILM specimens showed various a mount of microscopic ERM and 16(88.9%)of the ERM speci-mens showed various amount of ILM fra gments.The mean proportion of ERM within ILM specime ns was 4.69%and that of ILM within ERM specimens was 51.5%.No sig-nificant recurrence of ERM was found.Conclusion Re-currence of ERM may be minimized by re moving residual microscopic ERM present on the ILM.I ndocyaninegreen-assisted ILM peeling in ERM su rgery appears to have favorable visual and anatomic o utcomes.展开更多
文摘Purpose To evaluate the clinical out come and quantify histologically the amount of microscopic internal limiting membrane(ILM)and epiretinal membrane(ERM)pre-sent in ILM and ERM specimens obtained from ERM surgery.Design Interventional con secutive case series.Methods Patients scheduled for ERM s urgery were re-cruited prospectively.Pars plana v itrectomy,removal of ERM,and ILM peeling with indocyanin e green(ICG)staining were performed in all patie nts.Epiretinal mem-brane and ILM specimens were sent for histologic exam-ination.The amount of ERM present in ILM specimens and the amount of ILM present in ERM sp ecimens were quantified by manual counting.Outc ome measures in-clude change in best corrected visual acuity(BCVA),proportion of cases with 2or more lin es of visual im-provement,anatomic outcome,proportions of microscopic ERM within ILM,and microscopic ILM w ithin ERM.Results Eighteen eyes in 18patients were operated with a mean follow-up of 19.3months.There were 13primary ERMs and five secondary ERMs.The mea n logMAR BC-VA improved from 0.83preoperatively to 0.49postop-eratively(P<0.001).The mean lines of improvement in BCVA was 3.3lines with 14patients(77.8%)who had 2or more lines of BCVA improvemen t.Histologic e-valuation of the specimens showed no significant correla-tion with the final BCVA of 20/50or better.Eleven(61.1%)of the ILM specimens showed various a mount of microscopic ERM and 16(88.9%)of the ERM speci-mens showed various amount of ILM fra gments.The mean proportion of ERM within ILM specime ns was 4.69%and that of ILM within ERM specimens was 51.5%.No sig-nificant recurrence of ERM was found.Conclusion Re-currence of ERM may be minimized by re moving residual microscopic ERM present on the ILM.I ndocyaninegreen-assisted ILM peeling in ERM su rgery appears to have favorable visual and anatomic o utcomes.
