目的比较学龄前患儿全麻术后在不同时机拔除喉罩(laryngeal mask airway,LMA)的安全性和舒适性。方法选择2020年7月1日至12月31日在复旦大学附属眼耳鼻喉科医院行择期全麻眼科手术的患儿120例,年龄2~6岁,随机分为自主体动(spontaneous b...目的比较学龄前患儿全麻术后在不同时机拔除喉罩(laryngeal mask airway,LMA)的安全性和舒适性。方法选择2020年7月1日至12月31日在复旦大学附属眼耳鼻喉科医院行择期全麻眼科手术的患儿120例,年龄2~6岁,随机分为自主体动(spontaneous body movement,SBM)组和非自主体动(none body movement,NBM)组,每组60例,根据患儿体重选择合适型号的可弯曲喉罩静(FLMA)。麻醉诱导使用静脉推注丙泊酚完成,术中麻醉使用吸入七氟醚维持。手术结束后患儿入复苏室(postanesthesia care unit,PACU),SBM组在达到有效自主呼吸并出现自主体动时拔除喉罩,NBM组在达到有效自主呼吸未出现自主体动时拔除喉罩。记录患儿PACU停留期间的呼吸相关不良事件,包括呛咳、屏气>5 s、躁动、喉痉挛、氧饱和度降低(SpO_(2)≤94%)的情况,并记录患儿的拔管时间和出PACU时间。术日晚间随访并采用FLACC量表评估患儿疼痛,术后一日随访并采用焦虑自评量表(selfrating anxiety scale,SAS量表)评估患儿的睡眠质量以及患儿家长的焦虑程度和满意度。结果SBM组PACU停留期间呛咳、躁动发生例数显著高于NBM组,两组间屏气、喉痉挛、氧饱和度降低的发生例数差异无统计学意义。SBM组拔管时间显著长于NBM组,两组间PACU停留时间及术日晚间患儿的FLACC评分差异无统计学意义。两组间次日随访患儿的睡眠质量和家长焦虑程度、满意度差异无统计学意义。结论学龄前儿童患者术后达到有效自主呼吸后选择在未出现自主体动时拔除喉罩,呛咳及躁动的发生更少。展开更多
The activities of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R),superoalde dismutase (SOD) and the contents of malondialdehyde (MDA) and free radicals were measured, and the morphological changes wer...The activities of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R),superoalde dismutase (SOD) and the contents of malondialdehyde (MDA) and free radicals were measured, and the morphological changes were observed in the lens of control rats, selenium-deficient (SeD) and/or vitamin E deficient (VED) rats. The activities of GSH-Px in the lens of SeD rats decreased significantly. The GSH-Px activities of lens were positively related to erythrocytes selenium level. There was a free radical at g = 2.0015 in the rat lens of all groupe, but the content of free radicals in the lens of SeD group was significantly higher than that of the control group. The free radical content of lens was negatively related to erythrocytes selenium level, as well as the GSH-Px activities in the lens. In vitro, ultraviolet radiation caused the generation of another kind of free radical (g = 2.0097) in the lens of all groups, but the amount of the free radical in the lens of the SeD group was also significantly higher than that of the control group. The activities of SoD and GSSG-R in VED rat lens were significantly decreased. The amount of MDA in the lens of SeD and/or VED rats were significantly increased. The results showed that the decrease of antioaldative capability in the lenses of SeD and/or VED rats accelerated the lipid peroxidation and generation of free radicals. Although only early morphological changes in SeD and/or VED rat lens were observed, it is considered that selenium and vitamin E deficiency may be involved in the occurrence of cataract展开更多
Heat treatment of spray deposition 10% SiCp/6066 ( φ (SiCp)=10%) composites was investigated by means of hardness measurement. The results show that heat treatment technology is influenced by the presence of SiC part...Heat treatment of spray deposition 10% SiCp/6066 ( φ (SiCp)=10%) composites was investigated by means of hardness measurement. The results show that heat treatment technology is influenced by the presence of SiC particles. Compared with the base alloy 6066, the composites have lower burning temperature and is burnt at 540 ℃ due to the enrichment of Mg and Cu atoms in the SiCp/6066 interfaces. As a result, solution treatment of the composites should be carried out at lower temperature. The aging parameter values such as the aging temperature, the precipitation temperature of β′ and β phases, as well as the peak aging time, become lower. The optimum heat treatment process conditions are that the composites are solution treated at 515 ℃ and aged at 165 ℃ for 5 h.展开更多
Biochemical evidence on lens culture suggests that antioxidant nutrients can protect lens against peroxidation caused by radiation. A case-control study was carried out on 262 middle aged (45-54) and aged (55-64) subj...Biochemical evidence on lens culture suggests that antioxidant nutrients can protect lens against peroxidation caused by radiation. A case-control study was carried out on 262 middle aged (45-54) and aged (55-64) subjects. The relationship between biochemical markers of antioxidant status and senile lens changes (including cataract) was examined in 131 subjects with senile lens changes and 131 control subjects with clear lens. Antioxidant status was measured using plasma and erythrocyte glutathione peroxidase, erythrocyte superoxide dismutase and catalase activity and plasma levels of vitamine E and vitamin A. Subjects were grouped by age and sex. The results were as follows: (1) The subjects with lens changes tended to have lower plasma levels of vitamin E and vitamin A, lower activity of several antioxidant enzymes and higher level of MDA. (2) The subjects with senile lens changes had significantly lower erythrocyte glutathione peroxidase level.(3) In the middle-aged group, subjects with senile lens changes were observed to have lower erythrocyte and plasma glutathione peroxidase level than those without senile lens changes.The results suggest that appropriate amount of antoxidant nutrients might be expected to prevent or retard the process of lens changes展开更多
文摘目的比较学龄前患儿全麻术后在不同时机拔除喉罩(laryngeal mask airway,LMA)的安全性和舒适性。方法选择2020年7月1日至12月31日在复旦大学附属眼耳鼻喉科医院行择期全麻眼科手术的患儿120例,年龄2~6岁,随机分为自主体动(spontaneous body movement,SBM)组和非自主体动(none body movement,NBM)组,每组60例,根据患儿体重选择合适型号的可弯曲喉罩静(FLMA)。麻醉诱导使用静脉推注丙泊酚完成,术中麻醉使用吸入七氟醚维持。手术结束后患儿入复苏室(postanesthesia care unit,PACU),SBM组在达到有效自主呼吸并出现自主体动时拔除喉罩,NBM组在达到有效自主呼吸未出现自主体动时拔除喉罩。记录患儿PACU停留期间的呼吸相关不良事件,包括呛咳、屏气>5 s、躁动、喉痉挛、氧饱和度降低(SpO_(2)≤94%)的情况,并记录患儿的拔管时间和出PACU时间。术日晚间随访并采用FLACC量表评估患儿疼痛,术后一日随访并采用焦虑自评量表(selfrating anxiety scale,SAS量表)评估患儿的睡眠质量以及患儿家长的焦虑程度和满意度。结果SBM组PACU停留期间呛咳、躁动发生例数显著高于NBM组,两组间屏气、喉痉挛、氧饱和度降低的发生例数差异无统计学意义。SBM组拔管时间显著长于NBM组,两组间PACU停留时间及术日晚间患儿的FLACC评分差异无统计学意义。两组间次日随访患儿的睡眠质量和家长焦虑程度、满意度差异无统计学意义。结论学龄前儿童患者术后达到有效自主呼吸后选择在未出现自主体动时拔除喉罩,呛咳及躁动的发生更少。
文摘The activities of glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R),superoalde dismutase (SOD) and the contents of malondialdehyde (MDA) and free radicals were measured, and the morphological changes were observed in the lens of control rats, selenium-deficient (SeD) and/or vitamin E deficient (VED) rats. The activities of GSH-Px in the lens of SeD rats decreased significantly. The GSH-Px activities of lens were positively related to erythrocytes selenium level. There was a free radical at g = 2.0015 in the rat lens of all groupe, but the content of free radicals in the lens of SeD group was significantly higher than that of the control group. The free radical content of lens was negatively related to erythrocytes selenium level, as well as the GSH-Px activities in the lens. In vitro, ultraviolet radiation caused the generation of another kind of free radical (g = 2.0097) in the lens of all groups, but the amount of the free radical in the lens of the SeD group was also significantly higher than that of the control group. The activities of SoD and GSSG-R in VED rat lens were significantly decreased. The amount of MDA in the lens of SeD and/or VED rats were significantly increased. The results showed that the decrease of antioaldative capability in the lenses of SeD and/or VED rats accelerated the lipid peroxidation and generation of free radicals. Although only early morphological changes in SeD and/or VED rat lens were observed, it is considered that selenium and vitamin E deficiency may be involved in the occurrence of cataract
基金The Key Program of the 9th Five year Plan of China! (No .95 YS 0 0 4)
文摘Heat treatment of spray deposition 10% SiCp/6066 ( φ (SiCp)=10%) composites was investigated by means of hardness measurement. The results show that heat treatment technology is influenced by the presence of SiC particles. Compared with the base alloy 6066, the composites have lower burning temperature and is burnt at 540 ℃ due to the enrichment of Mg and Cu atoms in the SiCp/6066 interfaces. As a result, solution treatment of the composites should be carried out at lower temperature. The aging parameter values such as the aging temperature, the precipitation temperature of β′ and β phases, as well as the peak aging time, become lower. The optimum heat treatment process conditions are that the composites are solution treated at 515 ℃ and aged at 165 ℃ for 5 h.
文摘Biochemical evidence on lens culture suggests that antioxidant nutrients can protect lens against peroxidation caused by radiation. A case-control study was carried out on 262 middle aged (45-54) and aged (55-64) subjects. The relationship between biochemical markers of antioxidant status and senile lens changes (including cataract) was examined in 131 subjects with senile lens changes and 131 control subjects with clear lens. Antioxidant status was measured using plasma and erythrocyte glutathione peroxidase, erythrocyte superoxide dismutase and catalase activity and plasma levels of vitamine E and vitamin A. Subjects were grouped by age and sex. The results were as follows: (1) The subjects with lens changes tended to have lower plasma levels of vitamin E and vitamin A, lower activity of several antioxidant enzymes and higher level of MDA. (2) The subjects with senile lens changes had significantly lower erythrocyte glutathione peroxidase level.(3) In the middle-aged group, subjects with senile lens changes were observed to have lower erythrocyte and plasma glutathione peroxidase level than those without senile lens changes.The results suggest that appropriate amount of antoxidant nutrients might be expected to prevent or retard the process of lens changes
