Objective: To study the predictive value of serum electrolyte combined with glomerular filtration rate (GFR) evaluation equation for prognosis of severe obstructive renal injury. Methods: A total of 69 patients with c...Objective: To study the predictive value of serum electrolyte combined with glomerular filtration rate (GFR) evaluation equation for prognosis of severe obstructive renal injury. Methods: A total of 69 patients with calculous obstructive renal impairment admitted to our hospital from May 2017 to December 2018 were selected as the research objects. Clinical data of the patients were collected, and according to the status of renal function impairment, they were divided into 37 cases of mild to moderate, 32 cases of severe, and 40 cases of health examination in the same period as the control group. The fasting serum of the subjects was separated in the morning, and the serum electrolytes and related indicators were detected by Olympus AV640 automatic biochemical analyzer, Scr-CysC GFR evaluation equation was used to calculate the GFR score of all subjects, the levels of serum sodium, potassium and GFR scores in patients with severe obstructive renal injury with different prognostic outcomes were analyzed, subject operating characteristic curve (ROC) of prognostic indicators in patients with severe obstructive renal impairment was drawn, and the prognostic values of serum Na+, K+, GFR score and their combination in patients with severe obstructive renal damage were analyzed. Results: Compared with the control group, the levels of UmAb, CysC, Scr, BUN, TC, serum sodium and potassium in mild to moderate group and severe group increased in turn, and the GFR score decreased in turn (P < 0.05). The serum sodium and potassium concentrations increased in turn and the GFR score decreased in turn at 1 month after operation (P < 0.05). Compared with the 1 day before operation, the serum sodium and potassium concentrations in mild group and severe group decreased and the GFR score increased 1 month after operation (P < 0.05). Compared with the good prognosis group, the serum sodium and potassium levels in patients with severe obstructive renal damage in the poor prognosis group increased significantly, and the GFR score decreased significantly (P<0.05). The results of ROC showed that the combined detection of Na + concentration, K+ concentration and GFR score had an AUC of 0.936 for predicting the prognosis and outcomes of patients with severe renal injury, which was significantly higher than that of the single detection (AUC of 0.796, 0.815 and 0.810, respectively). Conclusion: The serum sodium and potassium levels in patients with severe obstructive renal impairment are increased, and the GFR score is decreased. The combined detection of the three factors has certain reference value in predicting the poor prognosis of patients with severe obstructive renal impairment.展开更多
目的了解男男性行为人群(men who have sex with men,MSM)主要交友程序使用情况,分析其人口学特征、性行为特点及艾滋病和梅毒感染状况,为开展针对性的干预措施提供依据。方法通过MSM社区组织发布信息招募MSM调查对象,使用统一的电子问...目的了解男男性行为人群(men who have sex with men,MSM)主要交友程序使用情况,分析其人口学特征、性行为特点及艾滋病和梅毒感染状况,为开展针对性的干预措施提供依据。方法通过MSM社区组织发布信息招募MSM调查对象,使用统一的电子问卷进行面对面调查,并采集静脉血液进行艾滋病、梅毒的血清学检测。结果共调查4651名MSM,按主要使用交友程序分为3组:Blued组2160人(46.44%),微信组2113人(45.43%),QQ组378人(8.13%)。本地居住时间<3月的比例最高为Blued组(6.9%),本地居住时间≥12月比例最高为微信组(92.1%),差异有统计学意义(χ2=60.326,P<0.001)。Blued组和微信组艾滋病防治知识知晓率、自我认同性取向为同性恋的比例均高于QQ组(均有P<0.05)。Blued组最近6个月发生男男群交行为的比例最高(8.1%),其次是QQ组(6.9%)和微信组(5.3%)(χ2=13.368,P=0.001)。Blued组、微信组和QQ组艾滋病检出率分别是2.2%、3.0%和3.4%,差异无统计学意义(χ2=3.546,P=0.170)。Blued组、微信组和QQ组梅毒检出率分别是1.9%,3.7%和2.9%,三组间差异有统计学意义(χ2=14.017,P=0.001)。结论MSM使用不同交友程序在行为学特征上的差异,使其在感染性病的风险上不同,应根据各自的特点,开展针对性的干预措施。展开更多
基金supported by Shaanxi Natural Science Basic Research Project(2012018JM7154).
文摘Objective: To study the predictive value of serum electrolyte combined with glomerular filtration rate (GFR) evaluation equation for prognosis of severe obstructive renal injury. Methods: A total of 69 patients with calculous obstructive renal impairment admitted to our hospital from May 2017 to December 2018 were selected as the research objects. Clinical data of the patients were collected, and according to the status of renal function impairment, they were divided into 37 cases of mild to moderate, 32 cases of severe, and 40 cases of health examination in the same period as the control group. The fasting serum of the subjects was separated in the morning, and the serum electrolytes and related indicators were detected by Olympus AV640 automatic biochemical analyzer, Scr-CysC GFR evaluation equation was used to calculate the GFR score of all subjects, the levels of serum sodium, potassium and GFR scores in patients with severe obstructive renal injury with different prognostic outcomes were analyzed, subject operating characteristic curve (ROC) of prognostic indicators in patients with severe obstructive renal impairment was drawn, and the prognostic values of serum Na+, K+, GFR score and their combination in patients with severe obstructive renal damage were analyzed. Results: Compared with the control group, the levels of UmAb, CysC, Scr, BUN, TC, serum sodium and potassium in mild to moderate group and severe group increased in turn, and the GFR score decreased in turn (P < 0.05). The serum sodium and potassium concentrations increased in turn and the GFR score decreased in turn at 1 month after operation (P < 0.05). Compared with the 1 day before operation, the serum sodium and potassium concentrations in mild group and severe group decreased and the GFR score increased 1 month after operation (P < 0.05). Compared with the good prognosis group, the serum sodium and potassium levels in patients with severe obstructive renal damage in the poor prognosis group increased significantly, and the GFR score decreased significantly (P<0.05). The results of ROC showed that the combined detection of Na + concentration, K+ concentration and GFR score had an AUC of 0.936 for predicting the prognosis and outcomes of patients with severe renal injury, which was significantly higher than that of the single detection (AUC of 0.796, 0.815 and 0.810, respectively). Conclusion: The serum sodium and potassium levels in patients with severe obstructive renal impairment are increased, and the GFR score is decreased. The combined detection of the three factors has certain reference value in predicting the poor prognosis of patients with severe obstructive renal impairment.
文摘目的了解男男性行为人群(men who have sex with men,MSM)主要交友程序使用情况,分析其人口学特征、性行为特点及艾滋病和梅毒感染状况,为开展针对性的干预措施提供依据。方法通过MSM社区组织发布信息招募MSM调查对象,使用统一的电子问卷进行面对面调查,并采集静脉血液进行艾滋病、梅毒的血清学检测。结果共调查4651名MSM,按主要使用交友程序分为3组:Blued组2160人(46.44%),微信组2113人(45.43%),QQ组378人(8.13%)。本地居住时间<3月的比例最高为Blued组(6.9%),本地居住时间≥12月比例最高为微信组(92.1%),差异有统计学意义(χ2=60.326,P<0.001)。Blued组和微信组艾滋病防治知识知晓率、自我认同性取向为同性恋的比例均高于QQ组(均有P<0.05)。Blued组最近6个月发生男男群交行为的比例最高(8.1%),其次是QQ组(6.9%)和微信组(5.3%)(χ2=13.368,P=0.001)。Blued组、微信组和QQ组艾滋病检出率分别是2.2%、3.0%和3.4%,差异无统计学意义(χ2=3.546,P=0.170)。Blued组、微信组和QQ组梅毒检出率分别是1.9%,3.7%和2.9%,三组间差异有统计学意义(χ2=14.017,P=0.001)。结论MSM使用不同交友程序在行为学特征上的差异,使其在感染性病的风险上不同,应根据各自的特点,开展针对性的干预措施。
