二氟[2,2]对环番的研究(Ⅰ)——催化裂解法制备二氟[2,2]对环番

[2,2]对环番([2,2]Paracyclophane)及其衍生物,具有特殊的分子结构和化学物理性能,在理论和实际应用方面受到很大的重视[1,2]。曾有人报导用2-氟-4-甲基-1-苄基三甲基氢氧化铵■热分解制成聚2-氟对苯撑-■。

Synthesis and Structure Determination of Ruthenium and Osmium Complexes with 2，6－Bis （diphenylphosphinomethyl） Pyridine

Bis(diphenylphosphinomethyl) pyridine(PNP)reaction with Na2OsCl6 - 6H2O to give the five coordinated,sixteen-electron complex Os(PNP)Cl2,.In the presence of formaldehyde,the reaction between Na2OsCl6 6H2O and PNP proceeds rapidly in boiling ethanol to give the coordinately saturated Os(PNP)Cl2(CO).The IR spectrum of Os (PNP)Cl2(CO)shows a strong absorption band at 1970 cm-1assignable to vco stretch. PNP reacts with RuCl2(PPh3),and RuCl2(DMSO)4(DMSO=dimethyl sulfoxide)to give Ru (PNP)CI2(PPh3)and Ru (PNP)Cl2(DMSO)respectively.The average Ru-CI, Ru-P and Ru-N bond distance in Ru (PNP)Cl2 (PPh3) determlneby X-ray crystallography are 0. 242, 0. 236 and 0. 216 nm, respectively.

用于细胞成像的溶酶体pH荧光探针研究进展

溶酶体是真核细胞中的酸性亚细胞器,酸性生理环境异常会导致其功能紊乱,引发一系列疾病.开发用于细胞成像的溶酶体pH荧光探针在一些疾病的诊断方面具有重要意义.本文主要从分子设计和光诱导电子转移、分子内电荷转移、荧光共振能量转移等识别机理对近几年溶酶体pH荧光探针的相关研究进行概述,同时,对其发展趋势与应用前景作了展望.