An innovative sandwich-structural Fe-based metal-organic framework magnetic material(Fe_(3)O_(4)@SWMIL-101-NH_(2))was fabricated using a facile solvothermal method.The characteristic properties of the material were in...An innovative sandwich-structural Fe-based metal-organic framework magnetic material(Fe_(3)O_(4)@SWMIL-101-NH_(2))was fabricated using a facile solvothermal method.The characteristic properties of the material were investigated by field emission scanning electron microscopy,transmission electron microscopy(TEM),energy-dispersive X-ray spectroscopy,Fourier transform infrared spectroscopy,X-ray powder diffraction,vibrating sample magnetometry,and Brunauer-Emmett-Teller measurements.Fe_(3)O_(4)@SW-MIL-101-NH_(2) is associated with advantages,such as robust magnetic properties,high specific surface area,and satisfactory storage stability,as well as good selective recognition ability for chlorogenic acid(CA)and its metabolites via chelation,hydrogen bonding,and p-interaction.The results of the static adsorption experiment indicated that Fe_(3)O_(4)@SW-MIL-101-NH_(2) possessed a high adsorption capacity toward CA and its isomers,cryptochlorogenic acid(CCA)and neochlorogenic acid(NCA),and the adsorption behaviors were fitted using the Langmuir adsorption isotherm model.Then,a strategy using magnetic solid-phase extraction(MSPE)and ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry(UPLC-Q-TOF MS/MS)was developed and successfully employed for the selective pre-concentration and rapid identification of CA metabolites in rat plasma,urine,and feces samples.This work presents a prospective strategy for the synthesis of magnetic adsorbents and the high-efficiency pretreatment of CA metabolites.展开更多
We aim to report an uncommon presentation of retinoblastoma and its management.A 4-year-old boy presented with left eye pain for 1 week with eye redness after being hit by a ball.On examination,the visual acuity in hi...We aim to report an uncommon presentation of retinoblastoma and its management.A 4-year-old boy presented with left eye pain for 1 week with eye redness after being hit by a ball.On examination,the visual acuity in his right eye was 6/6 and left eye was no perception to light.The conjunctiva in his left eye was injected and cornea was edematous.There was pseudohypopyon inferiorly.Lens was opaque and there was no fundus view.Intraocular pressure was 50 mmHg.Patient was initially treated as phacolytic glaucoma with severe inflammation.B scan showed intralesional calcification with retinal detachment.CT orbit showed left intraocular mass with calcification and optic nerve involvement.Thus,our final diagnosis was left eye retinoblastoma.Patient was performed a enucleation with chemotherapy in left eye.One year after the treatment,there was no local and distant invasion of the tumor.Anterior inflammation is a rare form of masquerade syndrome associated with retinoblastoma.展开更多
基金sponsored by the Natural Science Foundation of Chongqing,China(Grant No.:cstc2019jcyj-msxmX0074)supported by the University of Macao(Grant No.:MYRG2019-00011-ICMS).
文摘An innovative sandwich-structural Fe-based metal-organic framework magnetic material(Fe_(3)O_(4)@SWMIL-101-NH_(2))was fabricated using a facile solvothermal method.The characteristic properties of the material were investigated by field emission scanning electron microscopy,transmission electron microscopy(TEM),energy-dispersive X-ray spectroscopy,Fourier transform infrared spectroscopy,X-ray powder diffraction,vibrating sample magnetometry,and Brunauer-Emmett-Teller measurements.Fe_(3)O_(4)@SW-MIL-101-NH_(2) is associated with advantages,such as robust magnetic properties,high specific surface area,and satisfactory storage stability,as well as good selective recognition ability for chlorogenic acid(CA)and its metabolites via chelation,hydrogen bonding,and p-interaction.The results of the static adsorption experiment indicated that Fe_(3)O_(4)@SW-MIL-101-NH_(2) possessed a high adsorption capacity toward CA and its isomers,cryptochlorogenic acid(CCA)and neochlorogenic acid(NCA),and the adsorption behaviors were fitted using the Langmuir adsorption isotherm model.Then,a strategy using magnetic solid-phase extraction(MSPE)and ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry(UPLC-Q-TOF MS/MS)was developed and successfully employed for the selective pre-concentration and rapid identification of CA metabolites in rat plasma,urine,and feces samples.This work presents a prospective strategy for the synthesis of magnetic adsorbents and the high-efficiency pretreatment of CA metabolites.
文摘We aim to report an uncommon presentation of retinoblastoma and its management.A 4-year-old boy presented with left eye pain for 1 week with eye redness after being hit by a ball.On examination,the visual acuity in his right eye was 6/6 and left eye was no perception to light.The conjunctiva in his left eye was injected and cornea was edematous.There was pseudohypopyon inferiorly.Lens was opaque and there was no fundus view.Intraocular pressure was 50 mmHg.Patient was initially treated as phacolytic glaucoma with severe inflammation.B scan showed intralesional calcification with retinal detachment.CT orbit showed left intraocular mass with calcification and optic nerve involvement.Thus,our final diagnosis was left eye retinoblastoma.Patient was performed a enucleation with chemotherapy in left eye.One year after the treatment,there was no local and distant invasion of the tumor.Anterior inflammation is a rare form of masquerade syndrome associated with retinoblastoma.
