Objective: To study the correlation of LSD1 and NDRG1 gene expression in ovarian cancer tissue with cancer cell migration and invasion. Methods: Patients with ovarian cancer who underwent surgical resection in Fufeng ...Objective: To study the correlation of LSD1 and NDRG1 gene expression in ovarian cancer tissue with cancer cell migration and invasion. Methods: Patients with ovarian cancer who underwent surgical resection in Fufeng County People's Hospital between March 2014 and July 2017 were selected as the research subjects, and the ovarian cancer tissue and adjacent tissue were collected after surgical resection to determine the expression of LSD1, NDRG1, migration genes and invasion genes. Results: LSD1, YKL40, COX2, Twist, IFITM1, CatL, CTHRC1, MMP2 and FUNDC1 mRNA expression in ovarian cancer tissue were significantly higher than those in adjacent tissue whereas NDRG1, E-cadherin and Wnt5a mRNA expression were significantly lower than those in adjacent tissue;YKL40, COX2, Twist, IFITM1, CatL, CTHRC1, MMP2 and FUNDC1 mRNA expression in ovarian cancer tissue with high LSD1 expression were significantly higher than those in ovarian tissue with low LSD1 expression whereas E-cadherin and Wnt5a gene mRNA expression were significantly lower than those in ovarian tissue with low LSD1 expression. Conclusion: The high LSD1 expression and low NDRG1 expression in ovarian cancer tissue can promote the migration and invasion of cancer cells.展开更多
In this paper several interpolation theorems on martingale Lorentz spaces are given.The proofs are based on the atomic decompositions of martingale Hardy spaces over weighted measure spaces.Applying the interpolation ...In this paper several interpolation theorems on martingale Lorentz spaces are given.The proofs are based on the atomic decompositions of martingale Hardy spaces over weighted measure spaces.Applying the interpolation theorems,we obtain some inequalities on martingale transform operator.展开更多
文摘Objective: To study the correlation of LSD1 and NDRG1 gene expression in ovarian cancer tissue with cancer cell migration and invasion. Methods: Patients with ovarian cancer who underwent surgical resection in Fufeng County People's Hospital between March 2014 and July 2017 were selected as the research subjects, and the ovarian cancer tissue and adjacent tissue were collected after surgical resection to determine the expression of LSD1, NDRG1, migration genes and invasion genes. Results: LSD1, YKL40, COX2, Twist, IFITM1, CatL, CTHRC1, MMP2 and FUNDC1 mRNA expression in ovarian cancer tissue were significantly higher than those in adjacent tissue whereas NDRG1, E-cadherin and Wnt5a mRNA expression were significantly lower than those in adjacent tissue;YKL40, COX2, Twist, IFITM1, CatL, CTHRC1, MMP2 and FUNDC1 mRNA expression in ovarian cancer tissue with high LSD1 expression were significantly higher than those in ovarian tissue with low LSD1 expression whereas E-cadherin and Wnt5a gene mRNA expression were significantly lower than those in ovarian tissue with low LSD1 expression. Conclusion: The high LSD1 expression and low NDRG1 expression in ovarian cancer tissue can promote the migration and invasion of cancer cells.
基金This work was supported by the National Natural Science Foundation of China (Grant No.10671147)
文摘In this paper several interpolation theorems on martingale Lorentz spaces are given.The proofs are based on the atomic decompositions of martingale Hardy spaces over weighted measure spaces.Applying the interpolation theorems,we obtain some inequalities on martingale transform operator.
