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核糖核酸降低食管癌患者放疗期间呕吐等不良反应的疗效观察 被引量:2
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作者 丁乃昕 孙秀锦 +5 位作者 黄蕾 张楠 陈震章 宋雪 吴俚容 周益琴 《中国现代医学杂志》 CAS 2018年第33期88-92,共5页
目的观察注射用核糖核酸Ⅱ对食管癌患者放射治疗(放疗)期间呕吐等不良反应的临床效果和安全性。方法选取2014年5月—2017年1月江苏省肿瘤医院放疗科收治的食管癌患者76例,随机分为对照组与观察组。对照组只接受放疗;观察组在接受放疗的... 目的观察注射用核糖核酸Ⅱ对食管癌患者放射治疗(放疗)期间呕吐等不良反应的临床效果和安全性。方法选取2014年5月—2017年1月江苏省肿瘤医院放疗科收治的食管癌患者76例,随机分为对照组与观察组。对照组只接受放疗;观察组在接受放疗的同时应用注射用核糖核酸Ⅱ辅助治疗。比较两组治疗前后呕吐等不良反应、药物不良反应发生情况及免疫力。结果与对照组比较,观察组呕吐和放射性食管炎发生率降低(P <0.05);观察组放疗总有效率(81.6%)较对照组(55.3%)提高(P <0.05),红细胞、白细胞及血小板数量升高(P <0.05);血清中CD3+、CD4+水平和CD4+/CD8+升高(P <0.05),而头晕发生率降低(P <0.05)。结论注射用核糖核酸Ⅱ具有降低食管癌放疗患者呕吐等副反应、保护血细胞及提高免疫力的作用,还能增强放疗效果。 展开更多
关键词 食管癌 呕吐 核糖核酸 放射治疗
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The effectiveness of a high-fidelity teaching simulation based on an NLN/Jeffries simulation in the nursing education theoretical framework and its influencing factors 被引量:2
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作者 Fen-Fen Zhu li-rong wu 《Chinese Nursing Research》 CAS 2016年第3期129-132,共4页
Objective: To investigate the effectiveness of a high-fidelity teaching simulation based on an NLN/Jeffries simulation in the nursing education theoretical framework and its influencing factors. Methods: A high-fide... Objective: To investigate the effectiveness of a high-fidelity teaching simulation based on an NLN/Jeffries simulation in the nursing education theoretical framework and its influencing factors. Methods: A high-fidelity teaching simulation on clinical nursing practices using intelligent human analogues was conducted with 200 students, and The Simulation Design Scale, and the Student Satisfaction and Self-Confidence in Learning Scale developed by the National League for Nursing were used to evaluate the training effectiveness and its influencing factors. Results: For the high-fidelity teaching simulation, students gave scores of 4.36± 0.54 points for satisfaction and 4.33 ± 0.46 points for Self-Confidence. The students highly rated the five dimensions of teaching design, i.e., teaching objectives/information, assistance/support for students, problem solving, guided feedback, and fidelity. The teaching design was closely correlated with the satisfaction of the high-fidelity teaching simulation and self-efficacy, and the dimensions of teaching objectives/informa- tion and assistance/support for students were particularly strong predictors of teaching effectiveness. Conclusions: A high-fidelity teaching simulation based on Jeffries' theoretical framework improved student satisfaction with the simulation and their Self-Confidence. In planning simulations, teachers should take into account five characteristics, i.e., teaching objectives/information on simulation education, assistance/support for students, problem solving, guided reflection, and fidelity, to achieve better teaching effectiveness. 展开更多
关键词 Jeffries simulation in nursing education High-?delity simulation education Teaching design Teaching satisfaction Self-ef?cacy
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