Cloud cover plays a pivotal role in assessing observational conditions for astronomical site-testing.Except for the fraction of observing time,its fragmentation also wields a significant influence on the quality of ni...Cloud cover plays a pivotal role in assessing observational conditions for astronomical site-testing.Except for the fraction of observing time,its fragmentation also wields a significant influence on the quality of nighttime sky clarity.In this article,we introduce the functionΓ∈[0,1],designed to comprehensively capture both the fraction of available observing time and its continuity.Leveraging in situ measurement data gathered at the Muztagh-Ata site between 2017 and 2021,we showcase the effectiveness of our approach.The statistical result illustrates that the Muztagh-Ata site affords approximately 122 nights that were absolutely clear and 205 very good nights annually,corresponding toΓ≥0.9 andΓ≥0.36 respectively.展开更多
Objective To prepare, characterize and evaluate the antioxidant activity of rutin-liposome（RL）. Methods Liposomes of rutin were prepared by film dispersion method and the encapsulation efficiency（EE） was determine...Objective To prepare, characterize and evaluate the antioxidant activity of rutin-liposome（RL）. Methods Liposomes of rutin were prepared by film dispersion method and the encapsulation efficiency（EE） was determined by RP-HPLC. Human umbilical vein endothelial cells（HUVECs） were injuried by H_2O_2 and treated with either free aqueous rutin or the RL delivery systems. The viability of HUVECs was determined by MTT and ELISA. Results The drug delivery system showed uniform rutin loaded nanoparticles with average particle size of（147.20 ± 1.42） nm, polydispersity index of（0.191 ± 0.003） nm, Zeta potential of（-20.0 ± 1.0） mV, and the drug EE was closed to 90.0%. The antioxidant effect of the drug delivery system to H_2O_2-damaged HUVECs showed that RL could increase injury cells viability compared to free aqueous rutin, which was accompanied with an obvious decrease in malondialdehyde（MDA）, lactate dehydrogenase（LDH） while increase the level of nitrogen oxide（NOS）. Conclusion The nanostructured RL is improved on the antioxidant effect and may be treating the different diseases caused by free radicals.展开更多
基金supported by the Chinese Academy of Science(CAS)“Light of West China”Program(No.2022_XBQNXZ_014)the Joint Research Fund in Astronomy under a cooperative agreement between the National Natural Science Foundation of China(NSFC),the Chinese Academy of Sciences(CAS)(grant No.U2031209)+1 种基金the Xinjiang Natural Science Foundation(grant No.2022D01A357)the National Natural Science Foundation of China(NSFC,grant No.11873081)。
文摘Cloud cover plays a pivotal role in assessing observational conditions for astronomical site-testing.Except for the fraction of observing time,its fragmentation also wields a significant influence on the quality of nighttime sky clarity.In this article,we introduce the functionΓ∈[0,1],designed to comprehensively capture both the fraction of available observing time and its continuity.Leveraging in situ measurement data gathered at the Muztagh-Ata site between 2017 and 2021,we showcase the effectiveness of our approach.The statistical result illustrates that the Muztagh-Ata site affords approximately 122 nights that were absolutely clear and 205 very good nights annually,corresponding toΓ≥0.9 andΓ≥0.36 respectively.
基金National Natural Science Foundation of China(81372579,81273537)the Construct Program of the Key Discipline in Hunan Province
文摘Objective To prepare, characterize and evaluate the antioxidant activity of rutin-liposome（RL）. Methods Liposomes of rutin were prepared by film dispersion method and the encapsulation efficiency（EE） was determined by RP-HPLC. Human umbilical vein endothelial cells（HUVECs） were injuried by H_2O_2 and treated with either free aqueous rutin or the RL delivery systems. The viability of HUVECs was determined by MTT and ELISA. Results The drug delivery system showed uniform rutin loaded nanoparticles with average particle size of（147.20 ± 1.42） nm, polydispersity index of（0.191 ± 0.003） nm, Zeta potential of（-20.0 ± 1.0） mV, and the drug EE was closed to 90.0%. The antioxidant effect of the drug delivery system to H_2O_2-damaged HUVECs showed that RL could increase injury cells viability compared to free aqueous rutin, which was accompanied with an obvious decrease in malondialdehyde（MDA）, lactate dehydrogenase（LDH） while increase the level of nitrogen oxide（NOS）. Conclusion The nanostructured RL is improved on the antioxidant effect and may be treating the different diseases caused by free radicals.
