中枢神经系统表面铁沉积症(superficial siderosis of the central nervous system,SSCNS)是一种因含铁血黄素沉积于软脑膜下、脑组织、脑神经和脊髓表面所导致的罕见神经系统变性综合征,1908年由Hamill首次报道。其特征性临床表现为:...中枢神经系统表面铁沉积症(superficial siderosis of the central nervous system,SSCNS)是一种因含铁血黄素沉积于软脑膜下、脑组织、脑神经和脊髓表面所导致的罕见神经系统变性综合征,1908年由Hamill首次报道。其特征性临床表现为:感音神经性耳聋、小脑共济失调、锥体束征阳性。展开更多
目的探讨使用经皮外固定复位器械联合椎体成形术(PVP)治疗老年胸腰椎压缩骨折的安全性和临床疗效。方法对2015年12月至2016年10月广东省人民医院收治的13例骨质疏松性椎体压缩骨折患者,经伤椎上下邻椎穿刺置钉,安装自行研制的经皮外固...目的探讨使用经皮外固定复位器械联合椎体成形术(PVP)治疗老年胸腰椎压缩骨折的安全性和临床疗效。方法对2015年12月至2016年10月广东省人民医院收治的13例骨质疏松性椎体压缩骨折患者,经伤椎上下邻椎穿刺置钉,安装自行研制的经皮外固定复位器械,根据术前计算及术中C型臂X线机监视结果复位局部后凸畸形,然后行伤椎PVP,术毕取出经皮置钉复位器械。评估手术前后腰痛视觉模拟量表(VAS)评分和伤椎椎体前后缘高度,记录围手术期并发症。结果所有患者均顺利完成手术,平均手术时间68 min(50~80 min),术中出血量5~20 m L(平均12 m L),平均骨水泥注射量6 m L(4~8 m L)。术后VAS评分较术前有明显改善[(2.4±1.3)vs(7.2±1.7)分,P<0.05];X线片提示伤椎椎体前后缘高度分别由术前(58±10)%、(83±11)%恢复至术后(89±11)%、(95±8)%,手术前后比较,差异有统计学意义(P<0.05)。1例骨水泥渗漏至上方椎间隙、2例渗漏至椎旁静脉丛、2例侧方渗漏。术后随访3~12个月(平均7.1个月),椎体形态无明显变化,椎体前缘高度未见明显丢失。结论对于老年胸腰椎压缩骨折患者,经皮外固定复位器械联合PVP具有椎弓根钉固定撑开复位和稳定椎体的作用,创伤小,操作简单,手术安全可控,初步临床应用效果满意。展开更多
目的:探讨C3椎板切除、C7椎板U形切除的改良椎板成形术治疗颈椎后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)术后颈椎矢状位参数变化及其对临床疗效的影响。方法:采用病例对照研究的方法,纳入99例OPLL患...目的:探讨C3椎板切除、C7椎板U形切除的改良椎板成形术治疗颈椎后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)术后颈椎矢状位参数变化及其对临床疗效的影响。方法:采用病例对照研究的方法,纳入99例OPLL患者。其中C3切除组42例,男22例,女20例,平均年龄61.4±9.23岁(39~78岁),采用C3椎板切除、C4-6椎板单开门、C7椎板U型切除。同期采用标准单开门椎管扩大成形术(C3开门组)患者57例,男31例,女26例,平均年龄59.3±8.65岁(41~79岁)。平均随访45.9±8.8个月,观察两组患者术前术后JOA、NDI评分,观察两组患者术前后颈椎生理曲度及C2-7 SVA值变化。对各组内颈椎是否保持前凸的患者分成亚组,对比亚组间JOA及NDI评分差异。对比C3开门组内行C3-6及C3-7开门的患者的矢状位参数变化值。结果:两组患者术前各项指标无统计学差异,至末次随访时两组患者的JOA及NDI评分均显著好转,末次随访JOA评分两组间无差异,而C3切除组的NDI(6.06±4.49)优于C3开门组(8.25±7.53)。末次随访时两组颈椎曲度均有不同程度的降低,C3切除组颈椎曲度对比术前无统计学差异(颈椎曲度变化值为3.30°±9.36°),而C3开门组有差异(颈椎曲度变化值为6.25°±10.22°),两组间颈椎曲度值及变化值均有统计学差异(P<0.05)。末次随访两组的C2-7 SVA均有不同程度的增加,对比术前SVA,C3切除组无统计学差异,而C3开门组有差异,两组间的C2-7 SVA值及变化值有统计学差异(P<0.05)。C3开门组患者中有30例行C3-6开门,27例行C3-7开门,两亚组患者的术前及末次随访的颈椎生理曲度及C2-7 SVA值均无统计学差异。末次随访时两组内颈椎前凸及后凸的病例的JOA,NDI评分变化,神经功能改善率均无统计学差异(P>0.05)。结论:C3椎板切除的改良椎板单开门成形术能有效维持术后颈椎生理曲度,在一定程度上减缓颈椎后路术后颈椎后凸畸形的进展。手术后颈椎矢状面参数的变化与患者的临床疗效无显著相关性。展开更多
The volatile oil of Artemisia argyi was extracted by ultrasonic assisted extraction, and the extraction rate of volatile oil was 0.68%. Thevolatile oil of A. argyi was emulsified with 1% Tween-80, and drug susceptibil...The volatile oil of Artemisia argyi was extracted by ultrasonic assisted extraction, and the extraction rate of volatile oil was 0.68%. Thevolatile oil of A. argyi was emulsified with 1% Tween-80, and drug susceptibility test was conducted with avian Escherichia coli. The results showedthat the volatile oil of A. argyi had antibacterial effect against avian E. coli, and the minimal inhibitory concentration was 50 mg/mL. Taking sixcommon antibiotics as the control, drug susceptibility test was conducted with volatile oil of A. argyi. The results showed that 10 strains of E. coliwere sensitive to the volatile oil of A. argyi, three of which had different degrees of resistance and one had the tendency of resistance.展开更多
[Objective] The precipitation conditions of salting out method for extracting shaddock peel pectin were studied.[Method] Taking shaddock peel as the raw material, the optimal technological conditions for pectin precip...[Objective] The precipitation conditions of salting out method for extracting shaddock peel pectin were studied.[Method] Taking shaddock peel as the raw material, the optimal technological conditions for pectin precipitation were obtained by precipitating shaddock peel under dif-ferent salting-out conditions.[Result] The optimal conditions of salting out method for precipitating shaddock peel pectin were as follows: aluminum sulfate saturated solution: pectin extract 1∶1, salting out time 60 min, salting out temperature 60℃, salting out pH 4, and the extraction rate reached 6.8%.[Conclusion] Precipitation of pectin through salting out method reduced the consumption of ethanol, energy consumption and production cost.展开更多
In order to improve the comprehensive utilization value of water chestnut peel and the income of farmers. Contents of crude protein （ CP）, total sugar and reducing sugar were taken as indicators. Effects of initial ...In order to improve the comprehensive utilization value of water chestnut peel and the income of farmers. Contents of crude protein （ CP）, total sugar and reducing sugar were taken as indicators. Effects of initial pH, ratio of yeast to fungi species, incubation time and liquid volume on production of single cell pro- tein （SCP） feed was studied, and technological conditions on production of SCP feed by water chestnut peel were optimized by orthogonal test. Results showed that the production of SCP feed by water chestnut peel was optimal when pH was 5.0, ratio of yeast to fungi species was 2： 1, fermentation time was 2 d and the liquid volume was 70 mL / 250 mL. Under the optimum conditions, content of fermentation CP was 64.25%, content of total sugar was 19.8%, content of reducing sugar was 5.0%, content of coarse fibre was 0.0% and content of ash was 8.04%.展开更多
目的 探讨C3椎板切除、保留C7棘突的改良椎管成形术治疗颈椎后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)的临床疗效,并分析该术式减少轴性疼痛的机制.方法 2014年2月至2016年3月共收治OPLL患者133例,按...目的 探讨C3椎板切除、保留C7棘突的改良椎管成形术治疗颈椎后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)的临床疗效,并分析该术式减少轴性疼痛的机制.方法 2014年2月至2016年3月共收治OPLL患者133例,按纳入及排除标准共纳入42例.采用病例对照研究的方法,改良手术组22例,男13例,女9例;年龄39~77岁,平均(56.2±9.75)岁;采用C3椎板切除、C4~C6椎板单开门、C7椎板上半部分切除保留C7棘突的改良椎管成形术治疗.同期采用标准单开门椎管扩大成形术(标准手术组)患者20例,即C3~C7椎板单开门减压术治疗,男12例,女8例;年龄41~75岁,平均(53.7±8.23)岁.临床疗效评价采用日本骨科协会(Japanese Orthopaedic Association Scores,JOA)评分、颈椎功能障碍指数(neck disability index,NDI)及切口疼痛视觉模拟评分(visual analogue scale,VAS),影像学疗效评价采用颈椎生理曲度及活动度,记录两组患者术后轴性症状发生率及其他术后并发症.结果 42例患者均得到随访,随访时间15~29个月,平均(22.9±4.5)个月.两组患者术前各项指标的差异均无统计学意义,术后及随访时两组患者的JOA评分及NDI均较术前明显好转;末次随访时两组患者JOA评分的差异无统计学意义,而改良手术组患者NDI平均为6.56%±4.78%,优于标准手术组9.25%±7.63%.改良手术组术后第1天切口疼痛VAS评分低于标准手术组,此后随访期间两组VAS评分的差异均无统计学意义.改良手术组术后颈椎曲度平均为12.32°±8.26°,标准手术组为11.56°±8.05°,两组的差异无统计学意义.改良手术组术后颈椎活动度平均为39.68°±5.52°,标准手术组为33.51°±7.39°,差异有统计学意义.8例(19%)患者术后轴性症状加重或新出现轴性症状,改良手术组3例(13.6%),标准手术组5例(30%),两组间差异无统计学意义.随访期间无脑脊液漏、脊髓损伤、切口感染、椎板塌陷、术后再关门、内固定失败及断裂等并发症发生.结论 C3椎板切除、保留C7棘突的改良椎管成形术手术减压效果满意,相较标准的椎管成形术更微创,且能减少术后轴性症状发生率并保持颈椎活动度.展开更多
文摘中枢神经系统表面铁沉积症(superficial siderosis of the central nervous system,SSCNS)是一种因含铁血黄素沉积于软脑膜下、脑组织、脑神经和脊髓表面所导致的罕见神经系统变性综合征,1908年由Hamill首次报道。其特征性临床表现为:感音神经性耳聋、小脑共济失调、锥体束征阳性。
文摘目的探讨使用经皮外固定复位器械联合椎体成形术(PVP)治疗老年胸腰椎压缩骨折的安全性和临床疗效。方法对2015年12月至2016年10月广东省人民医院收治的13例骨质疏松性椎体压缩骨折患者,经伤椎上下邻椎穿刺置钉,安装自行研制的经皮外固定复位器械,根据术前计算及术中C型臂X线机监视结果复位局部后凸畸形,然后行伤椎PVP,术毕取出经皮置钉复位器械。评估手术前后腰痛视觉模拟量表(VAS)评分和伤椎椎体前后缘高度,记录围手术期并发症。结果所有患者均顺利完成手术,平均手术时间68 min(50~80 min),术中出血量5~20 m L(平均12 m L),平均骨水泥注射量6 m L(4~8 m L)。术后VAS评分较术前有明显改善[(2.4±1.3)vs(7.2±1.7)分,P<0.05];X线片提示伤椎椎体前后缘高度分别由术前(58±10)%、(83±11)%恢复至术后(89±11)%、(95±8)%,手术前后比较,差异有统计学意义(P<0.05)。1例骨水泥渗漏至上方椎间隙、2例渗漏至椎旁静脉丛、2例侧方渗漏。术后随访3~12个月(平均7.1个月),椎体形态无明显变化,椎体前缘高度未见明显丢失。结论对于老年胸腰椎压缩骨折患者,经皮外固定复位器械联合PVP具有椎弓根钉固定撑开复位和稳定椎体的作用,创伤小,操作简单,手术安全可控,初步临床应用效果满意。
文摘目的:探讨C3椎板切除、C7椎板U形切除的改良椎板成形术治疗颈椎后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)术后颈椎矢状位参数变化及其对临床疗效的影响。方法:采用病例对照研究的方法,纳入99例OPLL患者。其中C3切除组42例,男22例,女20例,平均年龄61.4±9.23岁(39~78岁),采用C3椎板切除、C4-6椎板单开门、C7椎板U型切除。同期采用标准单开门椎管扩大成形术(C3开门组)患者57例,男31例,女26例,平均年龄59.3±8.65岁(41~79岁)。平均随访45.9±8.8个月,观察两组患者术前术后JOA、NDI评分,观察两组患者术前后颈椎生理曲度及C2-7 SVA值变化。对各组内颈椎是否保持前凸的患者分成亚组,对比亚组间JOA及NDI评分差异。对比C3开门组内行C3-6及C3-7开门的患者的矢状位参数变化值。结果:两组患者术前各项指标无统计学差异,至末次随访时两组患者的JOA及NDI评分均显著好转,末次随访JOA评分两组间无差异,而C3切除组的NDI(6.06±4.49)优于C3开门组(8.25±7.53)。末次随访时两组颈椎曲度均有不同程度的降低,C3切除组颈椎曲度对比术前无统计学差异(颈椎曲度变化值为3.30°±9.36°),而C3开门组有差异(颈椎曲度变化值为6.25°±10.22°),两组间颈椎曲度值及变化值均有统计学差异(P<0.05)。末次随访两组的C2-7 SVA均有不同程度的增加,对比术前SVA,C3切除组无统计学差异,而C3开门组有差异,两组间的C2-7 SVA值及变化值有统计学差异(P<0.05)。C3开门组患者中有30例行C3-6开门,27例行C3-7开门,两亚组患者的术前及末次随访的颈椎生理曲度及C2-7 SVA值均无统计学差异。末次随访时两组内颈椎前凸及后凸的病例的JOA,NDI评分变化,神经功能改善率均无统计学差异(P>0.05)。结论:C3椎板切除的改良椎板单开门成形术能有效维持术后颈椎生理曲度,在一定程度上减缓颈椎后路术后颈椎后凸畸形的进展。手术后颈椎矢状面参数的变化与患者的临床疗效无显著相关性。
基金Supported by Scientific Research and Technology Development Program of Guangxi ProvinceConstruction of Science and Technology Service Platform in Hezhou Agricultural Science and Tech-nology Park(GKN 14258003)Scientific Research Project of Hezhou University(HZU-JS201617)
文摘The volatile oil of Artemisia argyi was extracted by ultrasonic assisted extraction, and the extraction rate of volatile oil was 0.68%. Thevolatile oil of A. argyi was emulsified with 1% Tween-80, and drug susceptibility test was conducted with avian Escherichia coli. The results showedthat the volatile oil of A. argyi had antibacterial effect against avian E. coli, and the minimal inhibitory concentration was 50 mg/mL. Taking sixcommon antibiotics as the control, drug susceptibility test was conducted with volatile oil of A. argyi. The results showed that 10 strains of E. coliwere sensitive to the volatile oil of A. argyi, three of which had different degrees of resistance and one had the tendency of resistance.
基金Supported by Guangxi Scientific Research and Technology Development Plan "Construction of Science and Technology Service Platform of Hezhou Agricultural Science and Technology Park"(GKN14258003)Research Project of Hezhou University(HZUJS201617)
文摘[Objective] The precipitation conditions of salting out method for extracting shaddock peel pectin were studied.[Method] Taking shaddock peel as the raw material, the optimal technological conditions for pectin precipitation were obtained by precipitating shaddock peel under dif-ferent salting-out conditions.[Result] The optimal conditions of salting out method for precipitating shaddock peel pectin were as follows: aluminum sulfate saturated solution: pectin extract 1∶1, salting out time 60 min, salting out temperature 60℃, salting out pH 4, and the extraction rate reached 6.8%.[Conclusion] Precipitation of pectin through salting out method reduced the consumption of ethanol, energy consumption and production cost.
基金Supported by Guangxi Science and Technology Development Project:Construction of Technology Services Platform of Hezhou Agricultural Science and Technology Park(14258003)Guangxi Higher Education Teaching Reform Project:Research on Regional Academic Specialty Biological Experiment Teaching Mode Innovation and Service of Local Economy(2014JGZ145)
文摘In order to improve the comprehensive utilization value of water chestnut peel and the income of farmers. Contents of crude protein （ CP）, total sugar and reducing sugar were taken as indicators. Effects of initial pH, ratio of yeast to fungi species, incubation time and liquid volume on production of single cell pro- tein （SCP） feed was studied, and technological conditions on production of SCP feed by water chestnut peel were optimized by orthogonal test. Results showed that the production of SCP feed by water chestnut peel was optimal when pH was 5.0, ratio of yeast to fungi species was 2： 1, fermentation time was 2 d and the liquid volume was 70 mL / 250 mL. Under the optimum conditions, content of fermentation CP was 64.25%, content of total sugar was 19.8%, content of reducing sugar was 5.0%, content of coarse fibre was 0.0% and content of ash was 8.04%.
