The binding conformations of bidentate ligand DABCO(1,4-diazobicyclo [2,2,2]octane) to a series of p'p type zinc porphyrin dimers covalently linked with flexible alkoxy chain - O(CH2)(n)O- (n=2-10) are described b...The binding conformations of bidentate ligand DABCO(1,4-diazobicyclo [2,2,2]octane) to a series of p'p type zinc porphyrin dimers covalently linked with flexible alkoxy chain - O(CH2)(n)O- (n=2-10) are described by H-1 NMR and UV-vis spectroscopy. DABCO can bind inside the cavities of porphyrin dimers and form a ternary sandwich complex as the alkoxy chain length is long enough. The thermodynamic parameters which control the binding behavior are investigated.展开更多
The DNA nuclease-like activity of a water soluble manganese corrole 5, 10, 15-tris（N-methyl-4-pyridyl）- corrolatomanga- nese（III） （MnⅢTMPyC） has been investigated. MnⅢMPyC may bind strongly to DNA via outside ...The DNA nuclease-like activity of a water soluble manganese corrole 5, 10, 15-tris（N-methyl-4-pyridyl）- corrolatomanga- nese（III） （MnⅢTMPyC） has been investigated. MnⅢMPyC may bind strongly to DNA via outside groove binding mode as indicated by absorption spectra, viscosity measurements and CD spectra. MnInTMPyC exhibited excellent catalytic activity in the DNA oxidative cleavage in the presence of hydroperoxide.展开更多
基金the National Natural Science Foundation (29871018) and Tianjin Science and Technology Committee Foundation (983602611) of China
文摘The binding conformations of bidentate ligand DABCO(1,4-diazobicyclo [2,2,2]octane) to a series of p'p type zinc porphyrin dimers covalently linked with flexible alkoxy chain - O(CH2)(n)O- (n=2-10) are described by H-1 NMR and UV-vis spectroscopy. DABCO can bind inside the cavities of porphyrin dimers and form a ternary sandwich complex as the alkoxy chain length is long enough. The thermodynamic parameters which control the binding behavior are investigated.
基金supported by the National Natural Science Foundation of China(Nos.20771039,20871122, 20971046)National Key Foundation Research Development Project(973)Item of China(No.2007CB815306)
文摘The DNA nuclease-like activity of a water soluble manganese corrole 5, 10, 15-tris（N-methyl-4-pyridyl）- corrolatomanga- nese（III） （MnⅢTMPyC） has been investigated. MnⅢMPyC may bind strongly to DNA via outside groove binding mode as indicated by absorption spectra, viscosity measurements and CD spectra. MnInTMPyC exhibited excellent catalytic activity in the DNA oxidative cleavage in the presence of hydroperoxide.
