Evaluation of Application Effect of Silicon-containing Water-soluble Fertilizer on Fast Vegetables

[Objectives]The study aims to verify the application effect of silicon-containing water-soluble fertilizer on fast vegetables.[Methods]Two vegetable crops,rape and lettuce,were studied,and three treatments were set up,including treatment 1(conventional fertilization+foliar spraying of silicon-containing water-soluble fertilizer,treatment 2(conventional fertilization+foliar spraying of the same amount of clear water),and treatment 3(conventional fertilization).[Results]The yield of lettuce and rape in treatment 1 increased by 15.1%and 8.6%,respectively;compared with treatment 3,the yield of lettuce and rape rose by 18.6%and 10.9%,respectively.Variance analysis shows that the F values of lettuce and rape were 20.938 and 35.372,respectively,and the differences among various treatments were extremely significant.[Conclusions]The application of silicon-containing water-soluble fertilizer on lettuce and rape significantly increased their yield.

Cleavable bimetallic-organic polymers for ROS mediated cascaded cancer therapy under the guidance of MRI through tumor hypoxia relief strategy

Despite recent advances in tumor treatment, reactive oxygen species(ROS)-mediated therapy, such as photodynamic therapy(PDT) and chemical dynamic therapy(CDT), remains challenging mainly due to hypoxia in tumor microenviroment. Relieving the hypoxia of tumor tissue has been considered as an attractive strategy for enhancing efficacy of ROS-based cancer treatment.Herein, one cascaded platform was developed to overcome tumor hypoxia and synergistically enhance the effect of ROSmediated therapy. This platform is based on cleavable bimetallic metal organic polymers(DOX@Fe/Mn-THPPTK-PEG). As an efficient Fenton-like material, it could not only produce cytotoxic ·OH by catalyzing the decomposition of intracellular H2O2, but also generate O2 to alleviate tumor hypoxia. In addition, the DOX-loaded metal organic polymers(MOPs could be disrupted after being exposed to laser irradiation or/and treated with H2O2, and then release the DOX for chemotherapy. Overall, 3 therapies(hypoxia-relieved PDT, photo-enhanced CDT, and ROS-mediated chemotherapy) could be achieved simultaneously by such a smart platform. Furthermore, T1-weighted MRI imaging ability of the MOPs could be greatly improved under H2O2 treatment.Therefore, total four robust functions were realized in a simple platform. These findings demonstrate great clinical potentials of the MOPs for cancer theranostics.