A fiber-optic Raman spectrum sensor system is used for the fast diagnosis of esophageal cancer during clinical endoscopic examination.The system contains a 785nm exciting laser,a Raman fiber-optic probe with 7 large c...A fiber-optic Raman spectrum sensor system is used for the fast diagnosis of esophageal cancer during clinical endoscopic examination.The system contains a 785nm exciting laser,a Raman fiber-optic probe with 7 large core fibers and a focus lens,and a highly sensitive spectrum meter.The Raman spectrum of the tissue could be obtained within 1 second by using such a system. A signal baseline removal and denoising technology is used to improve the signal quality.A novel signal feature extraction method for differentiating the normal and esophageal cancer tissues is proposed,based on the differences in half-height width(HHW)in 1200cm^-1 to 1400cm^-1 frequency band and the ratios of the spectral integral energy between 1600cm^-1-1700cm^-1 and 1500cm^-1- 1600cm^-1 band.It shows a high specificity and effectivity for the diagnosis of esophageal cancer.展开更多
In this paper, we axe interested in the existence of three positive solutions to a BVP for p-Laplacian impulsive functional dynamic equations on a time scale. Using the five-functional fixed theory, we establish a Ban...In this paper, we axe interested in the existence of three positive solutions to a BVP for p-Laplacian impulsive functional dynamic equations on a time scale. Using the five-functional fixed theory, we establish a Banach space and an appropriate operator. In this paper, we combine the delta-nabla p-Laplacian BVP with impulsive functional dynamic equations, and obtain some new sufficient conditions for the existence of three positive solutions to the BVP, and our result here generalizes the previous related results.展开更多
基金multicenter clinical study of endoscopic diagnosis of early esophageal cancer(Grant No.SWH2016ZDCX3007)the State 111 Project(Grant No.B14039)+3 种基金Application of endoscopic minimally invasive technique in diagnosis and treatment of digestive tract injury and disease(Grant No.SWH2016ZDCX2011)Study of effect on fibroblast transdifferentiation and prevention of postoperative esophagus stenosis through regulating the TRADD(Grant No. 81470907)the National Natural Science Foundation of China(NSFC)(Grant Nos.51627806and 51875091)Application of Raman imaging in the diagnosis of gastric cancer(Grant No. cstc2015shmszx 10017).
文摘A fiber-optic Raman spectrum sensor system is used for the fast diagnosis of esophageal cancer during clinical endoscopic examination.The system contains a 785nm exciting laser,a Raman fiber-optic probe with 7 large core fibers and a focus lens,and a highly sensitive spectrum meter.The Raman spectrum of the tissue could be obtained within 1 second by using such a system. A signal baseline removal and denoising technology is used to improve the signal quality.A novel signal feature extraction method for differentiating the normal and esophageal cancer tissues is proposed,based on the differences in half-height width(HHW)in 1200cm^-1 to 1400cm^-1 frequency band and the ratios of the spectral integral energy between 1600cm^-1-1700cm^-1 and 1500cm^-1- 1600cm^-1 band.It shows a high specificity and effectivity for the diagnosis of esophageal cancer.
基金sponsored by the Natural Science Foundation of Shanxi Province(No.2011011002-3)
文摘In this paper, we axe interested in the existence of three positive solutions to a BVP for p-Laplacian impulsive functional dynamic equations on a time scale. Using the five-functional fixed theory, we establish a Banach space and an appropriate operator. In this paper, we combine the delta-nabla p-Laplacian BVP with impulsive functional dynamic equations, and obtain some new sufficient conditions for the existence of three positive solutions to the BVP, and our result here generalizes the previous related results.