<div style="text-align:justify;"> Focusing of an area array camera is an important step in making a high precision imaging camera. Its testing method needs special study. In this paper, a method of cam...<div style="text-align:justify;"> Focusing of an area array camera is an important step in making a high precision imaging camera. Its testing method needs special study. In this paper, a method of camera focusing is introduced. The defocusing depth of camera is calculated by using the frequency spectrum of defocused image. This method is especially suitable for the focusing of the Planar Array Camera, and avoids the complicated work of adjusting the focus plane of the planar array camera in the focusing process. </div>展开更多
Photothermal therapy(PTT)using near-infrared(NIR)light for tumor treatment has triggered extensive attentions because of its advantages of noninvasion and convenience.The current research on PTT usually uses lasers in...Photothermal therapy(PTT)using near-infrared(NIR)light for tumor treatment has triggered extensive attentions because of its advantages of noninvasion and convenience.The current research on PTT usually uses lasers in the first NIR window(NIR-I;700–900 nm)as irradiation source.However,the second NIR window(NIR-II;1000–1700 nm)especially NIRIIa window(1300–1400 nm)is considered much more promising in diagnosis and treatment as its superiority in penetration depth and maximum permissible exposure over NIR-I window.Hereby,we propose the use of laser excitation at 1275 nm,which is approved by Food and Drug Administration for physical therapy,as an attractive technique for PTT to balance of tissue absorption and scattering with water absorption.Specifically,CuS-PEG nanoparticles with similar absorption values at 1275 and 808 nm,a conventional NIR-I window for PTT,were synthesized as PTT agents and a comparison platform,to explore the potential of 1275 and 808 nm lasers for PTT,especially in deep-tissue settings.The results showed that 1275 nm laser was practicable in PTT.It exhibited much more desirable outcomes in cell ablation in vitro and deep-tissue antitumor capabilities in vivo compared to that of 808 nm laser.NIR-IIa laser illumination is superior to NIR-I laser for deep-tissue PTT,and shows high potential to improve the PTT outcome.展开更多
According to the characteristic of Grid geographical information system (GridGIS), data distribution, heterogeneity and diversity in the grid environment, combining the high demand for shared resources and the purpose...According to the characteristic of Grid geographical information system (GridGIS), data distribution, heterogeneity and diversity in the grid environment, combining the high demand for shared resources and the purpose to realize unified and efficient management and sharing of distributed and mass resources, this paper proposed a grid GIS application building program on a number of peer-to-peer global Managers designs. This paper discussed the building process of the application domain, the selection criteria of application domain manager, the database design of application domain, and every service function module design of application domain. The integration of the application domain builds the three-tier management system of the node, the application domain, and the global management. The spatial query tests of distributed environment have shown that, the application domain is established to manage and share the distributed resources efficiently, and enhance the business processing functions in the grid environment.展开更多
Developing advanced battery-type materials with abundant active sites,high conductivity,versatile morphologies,and hierarchically porous structures is crucial for realizing high-quality hybrid supercapacitors.Herein,h...Developing advanced battery-type materials with abundant active sites,high conductivity,versatile morphologies,and hierarchically porous structures is crucial for realizing high-quality hybrid supercapacitors.Herein,heterogeneous FeS@NiS is synthesized by cationic Co doping via surface-structure engineering.The density functional theory(DFT)theoretical calculations are firstly performed to predict the advantages of Co dopant by improving the OH^(−)adsorption properties and adjusting electronic structure,benefiting ions/electron transfer.The dynamic surface evolution is further explored which demonstrates that CoFeS@CoNiS could be quickly reconstructed to Ni(Co)Fe_(2)O_(4)during the charging process,while the unstable structure of the amorphous Ni(Co)Fe_(2)O_(4)results in partial conversion to Ni/Co/FeOOH at high potentials,which contributes to the more reactive active site and good structural stability.Thus,the free-standing electrode reveals excellent electrochemical performance with a superior capacity(335.6 mA h g^(−1),2684 F g^(−1))at 3 A g^(−1).Furthermore,the as-fabricated device shows a quality energy density of 78.1 W h kg^(−1)at a power density of 750 W kg^(−1)and excellent cycle life of 92.1%capacitance retention after 5000 cycles.This work offers a facile strategy to construct versatile morphological structures using electrochemical activation and holds promising applications in energy-related fields.展开更多
[Objectives]This study was conducted to investigate the application of Sargassum fusiforme(Harv.)Setch.in cigarettes.[Methods]Tobacco-specific nitrosamines in the smoke of cigarettes added with ethanol extract of S.fu...[Objectives]This study was conducted to investigate the application of Sargassum fusiforme(Harv.)Setch.in cigarettes.[Methods]Tobacco-specific nitrosamines in the smoke of cigarettes added with ethanol extract of S.fusiforme were determined,and the compounds related to the aroma of S.fusiforme were identified by flavor-smelling experiment.[Results]With the addition of the ethanol extract of S.fusiforme,the decrease in the total amount of four tobacco-specific nitrosamines in mainstream cigarette smoke reached 16.42%.The results of the flavor-smelling experiment showed that the aroma of S.fusiforme might be related to(R)-5,6,7,7A-tetrahydro-4,4,7A-trimethyl-2(4H)-benzofuranone,glycerol,ethyl palmitate,methyl palmitate,ethyl linoleate,methyl(Z,Z,Z)-9,12,15-octadecatrienoate,ethyl(Z,Z,Z)-9,12,15-octadecatrienoate,phytol,and tetradecanoic acid.[Conclusions]The ethanol extract of S.fusiforme has the potential function of reducing the content of tobacco-specific nitrosamines in smoke and improving the taste of cigarettes.展开更多
Based on the four dimensions of PCK,this paper investigates the professional development of rural PE teachers in Huaiji County by using the research methods of literature,questionnaire,interview and mathematical stati...Based on the four dimensions of PCK,this paper investigates the professional development of rural PE teachers in Huaiji County by using the research methods of literature,questionnaire,interview and mathematical statistics.Based on PCK related theories,this paper analyzes the current situation of professional development of rural PE teachers in Huaiji County,explores the problems existing in the process of professional development,and provides an optimal path for the professional development of rural PE teachers,so as to improve the teaching ability and classroom quality of rural PE teachers,and promote the further development of rural PE education under the background of new curriculum reform.Through the research,it is found that the shortcomings of rural PE teachers are:lack of situational knowledge;lack of understanding of the course content;not flexible use of teaching representation;low ability to identify the differences of students learning styles;lack of understanding of social environment,etc.展开更多
Using methods such as questionnaire survey and literature review,a survey was conducted on the professional development of physical education teachers in Huaiji County under the background of the new curriculum standa...Using methods such as questionnaire survey and literature review,a survey was conducted on the professional development of physical education teachers in Huaiji County under the background of the new curriculum standards.The research results found that physical education teachers in Huaiji County have a relatively good distribution structure in terms of teaching experience,age,and education level,but the gender ratio and professional title ratio need to be improved.In terms of professional competence,teachers have shown good performance in teaching implementation ability,but there is still room for improvement in teaching design ability.A certain proportion of teachers still express dissatisfaction with professional title promotion,hardware configuration satisfaction,salary and benefits,and school reward mechanisms.Based on this,this study proposes some measures to improve the professional development level of county-level physical education teachers,such as enhancing teachers teaching design and implementation abilities,strengthening the cultivation of technical action demonstration abilities,improving hardware configuration satisfaction and teaching effectiveness reflection level,strengthening guidance and support for teachers professional development,and enhancing the promotion and implementation of post employment training.展开更多
In recent years,the national higher education reform has proposed the concept of curriculum ideological and political education as a major element.This integration into the standardized training of general practice re...In recent years,the national higher education reform has proposed the concept of curriculum ideological and political education as a major element.This integration into the standardized training of general practice residents(commonly referred to as general resident training)is an unavoidable trend in the teaching field.Based on the actual situation of our unit at The First Affiliated Hospital of Xi’an Medical University,this paper emphasizes the necessity of incorporating ideological and political education into the general resident training curriculum,despite the absence of pertinent practical experience in how to effectively incorporate such courses into comprehensive residential training.In our hospital,we must assess the ideological and political education in the curriculum of general resident training,proposing a scientific,reasonable ideological and political education concept system for general practice courses,integrating ideological and political education with general practice resident training,and strengthening the team of ideological and political education physicians to teach them to carry out such education,this would foster enthusiasm and initiative.Strengthening admission education and training for general practice resident training,as well as regularly hosting symposiums to share ideas and understand the mission of doctors can provide effective experience for ideological and political education in general resident training courses.展开更多
Objective:Transdermal drug delivery systems represent a critical focus in the pharmaceutics field;however,their use is limited by the fact that many drugs usually pass through the skin with low permeability.Menthol is...Objective:Transdermal drug delivery systems represent a critical focus in the pharmaceutics field;however,their use is limited by the fact that many drugs usually pass through the skin with low permeability.Menthol is a common penetration enhancer because of its high penetration-enhancing efficiency and safety.Our research aimed to reveal the penetrationenhancing mechanisms of menthol via a multiscale study.Methods:First,the interaction of menthol with the stratum corneum was studied using vertical Franz diffusion cells obtained from the abdominal skin of rats as a model.Then,the skin samples were observed via transmission electron microscopy.Finally,the interaction of different concentrations of menthol with a mixed lipid model of the stratum corneum was investigated via molecular dynamics simulation using the GROMOS 54A7 force field on a microcosmic level.Results:At concentrations of 3.5%or lower,menthol changed the original structure of the stratum corneum to varying degrees,which increased its fluidity and facilitated the permeation and storage of menthol.Menthol increased the fluidity of the stratum corneum mainly via two mechanisms.First,menthol had strong hydrogen-bonding capability,and it could compete for the lipidelipid hydrogen bonding sites,thereby weakening the stability of the hydrogenbonding network connecting the skin lipids.In addition,menthol had strong affinity for cholesterol,probably due to their similar molecular structures,suggesting that the incorporation of menthol would increase the fluidity of the lipid membrane similarly to cholesterol.Conclusion:The penetration-enhancing mechanism of menthol was explained using in vitro and molecular dynamics simulation methods.These findings may advance the basic research of transdermal drug delivery systems and facilitate the discoveries of novel penetration enhancers.展开更多
Consistency between the brightness temperatures observed with a ground-based microwave radiometer and the brightness temperatures computed by forward modeling is important in many different data applications. Using th...Consistency between the brightness temperatures observed with a ground-based microwave radiometer and the brightness temperatures computed by forward modeling is important in many different data applications. Using the National Centers for Environmental Prediction-Final Operational Global Analysis (NCEP-FNL) dataset as a reference, the brightness temperature was obtained through the radiation transfer model for forward calculation. The problem of segmented features in long time of observational data from ground-based microwave radiometers (the so-called “jumping problem”) was identified. By analyzing the deviation and correlation between the observational bright temperature data and the forward calculated data under clear sky conditions, a revised scheme is proposed for the bright temperature observational data. Data obtained with a ground-based microwave radiometer in Beijing from January 1, 2010 to December 31, 2011 around the date of liquid nitrogen calibration show that the correlation between the observed brightness temperatures and the forward computed brightness temperatures is better after correction, especially at 28 and 30 GHz. The “jumping” problem in the observational data for the brightness temperature is eliminated after correction and the time continuity of the observational data and its consistency with the forward calculated data based on the NCEP-FNL dataset are improved. The proposed correction scheme can be used both for real-time data quality control and to improve the accuracy of historical datasets obtained with poorly calibrated microwave radiometers or radiometers working in polluted environments.展开更多
The process-based water system models have been transitioning from single-functional to integrated multi-objective and multi-functional since the worldwide digital upgrade of urban water system management.The prolifer...The process-based water system models have been transitioning from single-functional to integrated multi-objective and multi-functional since the worldwide digital upgrade of urban water system management.The proliferation of model complexity results in more significant uncertainty and computational requirements.However,conventional model calibration methods are insufficient in dealing with extensive computational time and limited monitoring samples.Here we introduce a novel machine learning system designed to expedite parameter optimization with limited data and boost efficiency in parameter search.MLPS,termed the machine learning parallel system for fast parameter search of integrated process-based models,aims to enhance both the performance and efficiency of the integrated model by ensuring its comprehensiveness,accuracy,and stability.MLPS was constructed upon the concept of model surrogation t algorithm optimization using Ant Colony Optimization(ACO)coupled with Long Short-Term Memory(LSTM).The optimization results of the Integrated sewer network and urban river model demonstrate that the average relative percentage difference of the predicted river pollutant concentrations increases from 1.1 to 6.0,and the average absolute percent bias decreases from 124.3%to 8.8%.The model outputs closely align with the monitoring data,and parameter calibration time is reduced by 89.94%.MLPS enables the efficient optimization of integrated process-based models,facilitating the application of highly precise complex models in environmental management.The design of MLPS also presents valuable insights for optimizing complex models in other fields.展开更多
Polynary transition-metal layered hydroxides are promising energy materials owing to their unique architecture,impressive theoretical capacities,and adjustable compositions.Regulating the dimensional morphology and ac...Polynary transition-metal layered hydroxides are promising energy materials owing to their unique architecture,impressive theoretical capacities,and adjustable compositions.Regulating the dimensional morphology and active sites/redox states are the keys to electrochemical performance enhancement.Distinguish from the reported mono-metal or binary-metal configurations,a new ternary-metal AlCoNi-LTH is coanchored onto a highly graphitized porous N-doped carbon matrix to develop superior 3D hierarchical microporous functional energy hybrids AlCoNi-LTHs/NAC.The constructed hybrids possess superior structural durability,good electrical conductivity,and rich active sites due to the strong interfacial conjunction and favorable synergistic effect between the doped porous carbon and AlCoNi nanosheets.Consequently,the AlCoNi-LTHs/NAC hybrids demonstrate high conductivity,reasonable specific surface area,and superior specific capacitance,and the assembled hybrid battery-type supercapacitor reveals an ideal energy density of 72.6 Wh kg^(-1)at a power density of 625 W kg^(-1),which is superior to the reported devices.This strategy opens a platform to rationally design polynary transition-metal layered hydroxides and their hybrids for efficient supercapacitors.展开更多
This study was designed to investigate the protective effects of Astaxanthin(AST)in rats with diabetes mellitus(DM)induced by streptozotocin.SD rats were divided into control group(n=5,only received normal saline),DM ...This study was designed to investigate the protective effects of Astaxanthin(AST)in rats with diabetes mellitus(DM)induced by streptozotocin.SD rats were divided into control group(n=5,only received normal saline),DM group(n=8)and AST+DM group(n=8;AST:50 mg/kg/day).DM rats were induced by intraperitoneal injection of streptozocin(STZ,65 mg/kg).Blood glucose level and body weight were determined at weeks 0,2,4,6 and 8,respectively.At week 8,kidney function was determined,together with expression of P53 and dynamin-related protein-1(Drp1)by Western blot analysis and immunofluorescence.AST led to increase of body weight in rats with DM.AST+DM group showed a significant decrease in blood glucose level at week 4 compared with DM group(P<0.05).AST improved renal function and significantly reduced expression of P53 and Drp1 in DM rats.In addition,AST can effectively reduce the blood glucose in DM rats,and delayed the pathogenesis of diabetic nephropathy.Such delay mediated by AST may be associated with the downregulation of Drp1 and P53.展开更多
Density functional theory(DFT) and time-dependent density functional theory(TDDFT) methods are used to investigate the influences of intramolecular and intermolecular hydrogen bonding on excited-state intramolecul...Density functional theory(DFT) and time-dependent density functional theory(TDDFT) methods are used to investigate the influences of intramolecular and intermolecular hydrogen bonding on excited-state intramolecular proton transfer(ESIPT) for the 4-N,N-(diethylamino)-2-hydroxybenzaldehyde(DEAHB). The structures of DEAHB and its hydrogenbonded complex in the ground-state and the excited-state are optimized. In addition, the detailed descriptions of frontier molecular orbitals of the DEAHB monomer and DEAHB-DMSO complex are presented. Moreover, the transition density matrix is worked out to gain deeper insight into the orbitals change. It is hoped that the present work not only elaborates different influence mechanisms between intramolecular and intermolecular hydrogen bonding interactions on the ESIPT process for DEAHB, but also may be helpful to design and develop new materials and applications involved DEAHB systems in the future.展开更多
In order to promote marker-assisted selection of Tan sheep, the polymorphism of OB gene in zan sheep was detected by sequencing and PCR-RFLP tech- niques. The correlation between polymorphism of OB gene and weight of ...In order to promote marker-assisted selection of Tan sheep, the polymorphism of OB gene in zan sheep was detected by sequencing and PCR-RFLP tech- niques. The correlation between polymorphism of OB gene and weight of Tan sheep was analyzed. The results indicated that there was a CT point mutation at locus 253 in exon 3 region of OB gene, but no mutant homozygote was found. The results of chi-square test showed that the frequency of BB and AB genotypes was con- sistent with Hardy-Weinberg equilibrium. AB genotype was the dominant genotype controlling weight of Tan sheep with the genotype frequency of 0.05. According to the results of correlation analysis, the mutation exerted significant effects on weight of Tan sheep at 3-month-old and 6-month-old (P 〈 0.05). Moreover, interac- tions between ~enotvoe and ~ender had no sianificant effect on weight of Tan sheen ( P 〉 0.05 ).展开更多
Tan sheep industry is a characteristic and superior agricultural industry in Ningxia,and it is also an enriching industry that helps in poverty alleviation and increases farmers’income.The local government has been c...Tan sheep industry is a characteristic and superior agricultural industry in Ningxia,and it is also an enriching industry that helps in poverty alleviation and increases farmers’income.The local government has been committing to building the"Yanchi Tan Sheep"brand and has made remarkable achievements.In order to explore the resource efficiency and quality of Tan sheep industry,the current situations and advantages of brand development,this paper made an empirical research through field investigations.The research was mainly concentrated on breeding scale,industrial integration,brand building,breeding benefits,and policy support.After a comprehensive evaluation,it came up with the recommendation that the Tan sheep industry should take the high-quality,high-end and green development road.展开更多
This study focused on the effect of glass structures of modern architecture on the indoor thermal environment during summer.In particular,this study examined how solar radiation significantly altered people’s thermal...This study focused on the effect of glass structures of modern architecture on the indoor thermal environment during summer.In particular,this study examined how solar radiation significantly altered people’s thermal sensations.Laboratory tests on convection–radiation air conditioning systems were conducted,encompassing 12 different scenarios,including diverse indoor open areas,terminal forms,and levels of solar radiation.These tests aimed to explore the physiological and psychological responses of the human body to solar radiation penetrating through windows into the inner room.During the experiments,the participants’subjective thermal sensations and thermal comfort were recorded,along with continuous monitoring of their physiological and environmental parameters.Results showed that solar radiation significantly increased local skin temperature,with a maximum rise of 2.15℃.Operative temperature is a reliable indicator of human skin temperature and thermal sensation vote(TSV).This study established two models that could predict the skin temperature of individuals indoors through operative temperature under conditions without or with solar radiation,and identified sensitive ranges of operative temperature for both models,to be specific,26.32℃to 28.43℃and 28.51℃to 34.11℃,respectively.Furthermore,this study established the relationship between skin temperature and TSV under conditions with and without solar radiation.The results indicate that solar radiation enhances the human body’s adaptability to indoor environmental parameters;a convection–radiation system(FC+RF)could be used to optimize indoor thermal control under solar radiation,achieving more stable environmental temperatures and improved indoor comfort.展开更多
The large-scale implementation of the Gully Stabilization and Land Reclamation(GSLR)project induces various failures of loess slopes due to excavation in Yan'an,China.However,the deformation and failure behavior o...The large-scale implementation of the Gully Stabilization and Land Reclamation(GSLR)project induces various failures of loess slopes due to excavation in Yan'an,China.However,the deformation and failure behavior of these excavated loess slopes have not been fully understood.In this study,field investigation was undertaken for analyzing the distributions and failure features of excavation-induced loess slope failures.It is found that plastic failure mainly occurs in Q_(3) loess layers and brittle failure in Q_(2).To understand the underlying failure mechanism,a series of triaxial shear tests were conducted on intact Q_(3) and Q_(2) loess samples that with different water contents,namely natural water content(natural),dry side of the natural value(drying 5%),and wet side(wetting 5%).The characteristics of stress-strain curves and failure modes of the samples were analyzed.Results show that the stress-strain curves of Q_(2) samples are dominated by strain-softening characteristics,while Q_(3) samples mainly exhibit strain-harden features except in the drying state.Correspondingly,shear failures of Q_(3) specimens are mainly caused by shear crack planes(single,X or V-shaped).For Q_(2) loess,the dominance of tensile cracks is observed on the surface of damaged specimens.These disclose the different failure modes of excavated slopes located in different strata,that is,the arc sliding failure of Q_(3) loess slopes and the stepped tensile failure of Q_(2) loess slopes,and are helpful in the design and management of the ongoing GSLR projects in the Loess Plateau.展开更多
文摘<div style="text-align:justify;"> Focusing of an area array camera is an important step in making a high precision imaging camera. Its testing method needs special study. In this paper, a method of camera focusing is introduced. The defocusing depth of camera is calculated by using the frequency spectrum of defocused image. This method is especially suitable for the focusing of the Planar Array Camera, and avoids the complicated work of adjusting the focus plane of the planar array camera in the focusing process. </div>
基金supported,in part,by the Natural Science Foundation of China (Nos.81402043 and 81201141)the Clinical Capability Construction Project for Liaoning Provincial Hospitals (LNCCC-D50-2015+1 种基金LNCCC-C09-2015)the China postdoctoral science foundation Grant (2016T90233)
文摘Photothermal therapy(PTT)using near-infrared(NIR)light for tumor treatment has triggered extensive attentions because of its advantages of noninvasion and convenience.The current research on PTT usually uses lasers in the first NIR window(NIR-I;700–900 nm)as irradiation source.However,the second NIR window(NIR-II;1000–1700 nm)especially NIRIIa window(1300–1400 nm)is considered much more promising in diagnosis and treatment as its superiority in penetration depth and maximum permissible exposure over NIR-I window.Hereby,we propose the use of laser excitation at 1275 nm,which is approved by Food and Drug Administration for physical therapy,as an attractive technique for PTT to balance of tissue absorption and scattering with water absorption.Specifically,CuS-PEG nanoparticles with similar absorption values at 1275 and 808 nm,a conventional NIR-I window for PTT,were synthesized as PTT agents and a comparison platform,to explore the potential of 1275 and 808 nm lasers for PTT,especially in deep-tissue settings.The results showed that 1275 nm laser was practicable in PTT.It exhibited much more desirable outcomes in cell ablation in vitro and deep-tissue antitumor capabilities in vivo compared to that of 808 nm laser.NIR-IIa laser illumination is superior to NIR-I laser for deep-tissue PTT,and shows high potential to improve the PTT outcome.
文摘According to the characteristic of Grid geographical information system (GridGIS), data distribution, heterogeneity and diversity in the grid environment, combining the high demand for shared resources and the purpose to realize unified and efficient management and sharing of distributed and mass resources, this paper proposed a grid GIS application building program on a number of peer-to-peer global Managers designs. This paper discussed the building process of the application domain, the selection criteria of application domain manager, the database design of application domain, and every service function module design of application domain. The integration of the application domain builds the three-tier management system of the node, the application domain, and the global management. The spatial query tests of distributed environment have shown that, the application domain is established to manage and share the distributed resources efficiently, and enhance the business processing functions in the grid environment.
基金financial support from the Chang Jiang Scholars Program (51073047)the National Natural Science Foundation of China (51773049)+5 种基金the China Aerospace Science and Technology Corporation-Harbin Institute of Technology Joint Center for Technology Innovation Fund (HIT15-1A01)the Harbin City Science and Technology Projects (2013DB4BP031 and RC2014QN017035)the Natural Science Foundation of Shandong Province of China (ZR2023QE071)the College Students’ Innovation and Entrepreneurship Training Program Projects of Shandong Province (S202211065048)the Scientific Research Foundation of Qingdao University (DC1900009425)the China Postdoctoral Science Foundation (2022TQ0282)
文摘Developing advanced battery-type materials with abundant active sites,high conductivity,versatile morphologies,and hierarchically porous structures is crucial for realizing high-quality hybrid supercapacitors.Herein,heterogeneous FeS@NiS is synthesized by cationic Co doping via surface-structure engineering.The density functional theory(DFT)theoretical calculations are firstly performed to predict the advantages of Co dopant by improving the OH^(−)adsorption properties and adjusting electronic structure,benefiting ions/electron transfer.The dynamic surface evolution is further explored which demonstrates that CoFeS@CoNiS could be quickly reconstructed to Ni(Co)Fe_(2)O_(4)during the charging process,while the unstable structure of the amorphous Ni(Co)Fe_(2)O_(4)results in partial conversion to Ni/Co/FeOOH at high potentials,which contributes to the more reactive active site and good structural stability.Thus,the free-standing electrode reveals excellent electrochemical performance with a superior capacity(335.6 mA h g^(−1),2684 F g^(−1))at 3 A g^(−1).Furthermore,the as-fabricated device shows a quality energy density of 78.1 W h kg^(−1)at a power density of 750 W kg^(−1)and excellent cycle life of 92.1%capacitance retention after 5000 cycles.This work offers a facile strategy to construct versatile morphological structures using electrochemical activation and holds promising applications in energy-related fields.
文摘[Objectives]This study was conducted to investigate the application of Sargassum fusiforme(Harv.)Setch.in cigarettes.[Methods]Tobacco-specific nitrosamines in the smoke of cigarettes added with ethanol extract of S.fusiforme were determined,and the compounds related to the aroma of S.fusiforme were identified by flavor-smelling experiment.[Results]With the addition of the ethanol extract of S.fusiforme,the decrease in the total amount of four tobacco-specific nitrosamines in mainstream cigarette smoke reached 16.42%.The results of the flavor-smelling experiment showed that the aroma of S.fusiforme might be related to(R)-5,6,7,7A-tetrahydro-4,4,7A-trimethyl-2(4H)-benzofuranone,glycerol,ethyl palmitate,methyl palmitate,ethyl linoleate,methyl(Z,Z,Z)-9,12,15-octadecatrienoate,ethyl(Z,Z,Z)-9,12,15-octadecatrienoate,phytol,and tetradecanoic acid.[Conclusions]The ethanol extract of S.fusiforme has the potential function of reducing the content of tobacco-specific nitrosamines in smoke and improving the taste of cigarettes.
基金Youth Innovation Talent Project of Guangdong Department of Education(2019WQNCX120)Key Project of Zhaoqing Education Development Research Institute(ZQJYY2016003)Quality Engineering and Teaching Reform Project of Zhaoqing University(zlgc201860).
文摘Based on the four dimensions of PCK,this paper investigates the professional development of rural PE teachers in Huaiji County by using the research methods of literature,questionnaire,interview and mathematical statistics.Based on PCK related theories,this paper analyzes the current situation of professional development of rural PE teachers in Huaiji County,explores the problems existing in the process of professional development,and provides an optimal path for the professional development of rural PE teachers,so as to improve the teaching ability and classroom quality of rural PE teachers,and promote the further development of rural PE education under the background of new curriculum reform.Through the research,it is found that the shortcomings of rural PE teachers are:lack of situational knowledge;lack of understanding of the course content;not flexible use of teaching representation;low ability to identify the differences of students learning styles;lack of understanding of social environment,etc.
基金Key Education Research Project of Zhaoqing Education Development Research Institute in 2023(ZQJYY2023016)Key Education Research Project of Zhaoqing Education Development Research Institute in 2016(ZQJYY2016003).
文摘Using methods such as questionnaire survey and literature review,a survey was conducted on the professional development of physical education teachers in Huaiji County under the background of the new curriculum standards.The research results found that physical education teachers in Huaiji County have a relatively good distribution structure in terms of teaching experience,age,and education level,but the gender ratio and professional title ratio need to be improved.In terms of professional competence,teachers have shown good performance in teaching implementation ability,but there is still room for improvement in teaching design ability.A certain proportion of teachers still express dissatisfaction with professional title promotion,hardware configuration satisfaction,salary and benefits,and school reward mechanisms.Based on this,this study proposes some measures to improve the professional development level of county-level physical education teachers,such as enhancing teachers teaching design and implementation abilities,strengthening the cultivation of technical action demonstration abilities,improving hardware configuration satisfaction and teaching effectiveness reflection level,strengthening guidance and support for teachers professional development,and enhancing the promotion and implementation of post employment training.
文摘In recent years,the national higher education reform has proposed the concept of curriculum ideological and political education as a major element.This integration into the standardized training of general practice residents(commonly referred to as general resident training)is an unavoidable trend in the teaching field.Based on the actual situation of our unit at The First Affiliated Hospital of Xi’an Medical University,this paper emphasizes the necessity of incorporating ideological and political education into the general resident training curriculum,despite the absence of pertinent practical experience in how to effectively incorporate such courses into comprehensive residential training.In our hospital,we must assess the ideological and political education in the curriculum of general resident training,proposing a scientific,reasonable ideological and political education concept system for general practice courses,integrating ideological and political education with general practice resident training,and strengthening the team of ideological and political education physicians to teach them to carry out such education,this would foster enthusiasm and initiative.Strengthening admission education and training for general practice resident training,as well as regularly hosting symposiums to share ideas and understand the mission of doctors can provide effective experience for ideological and political education in general resident training courses.
基金This work was supported by the Municipal Natural Science Foundation of Beijing(7162122).
文摘Objective:Transdermal drug delivery systems represent a critical focus in the pharmaceutics field;however,their use is limited by the fact that many drugs usually pass through the skin with low permeability.Menthol is a common penetration enhancer because of its high penetration-enhancing efficiency and safety.Our research aimed to reveal the penetrationenhancing mechanisms of menthol via a multiscale study.Methods:First,the interaction of menthol with the stratum corneum was studied using vertical Franz diffusion cells obtained from the abdominal skin of rats as a model.Then,the skin samples were observed via transmission electron microscopy.Finally,the interaction of different concentrations of menthol with a mixed lipid model of the stratum corneum was investigated via molecular dynamics simulation using the GROMOS 54A7 force field on a microcosmic level.Results:At concentrations of 3.5%or lower,menthol changed the original structure of the stratum corneum to varying degrees,which increased its fluidity and facilitated the permeation and storage of menthol.Menthol increased the fluidity of the stratum corneum mainly via two mechanisms.First,menthol had strong hydrogen-bonding capability,and it could compete for the lipidelipid hydrogen bonding sites,thereby weakening the stability of the hydrogenbonding network connecting the skin lipids.In addition,menthol had strong affinity for cholesterol,probably due to their similar molecular structures,suggesting that the incorporation of menthol would increase the fluidity of the lipid membrane similarly to cholesterol.Conclusion:The penetration-enhancing mechanism of menthol was explained using in vitro and molecular dynamics simulation methods.These findings may advance the basic research of transdermal drug delivery systems and facilitate the discoveries of novel penetration enhancers.
文摘Consistency between the brightness temperatures observed with a ground-based microwave radiometer and the brightness temperatures computed by forward modeling is important in many different data applications. Using the National Centers for Environmental Prediction-Final Operational Global Analysis (NCEP-FNL) dataset as a reference, the brightness temperature was obtained through the radiation transfer model for forward calculation. The problem of segmented features in long time of observational data from ground-based microwave radiometers (the so-called “jumping problem”) was identified. By analyzing the deviation and correlation between the observational bright temperature data and the forward calculated data under clear sky conditions, a revised scheme is proposed for the bright temperature observational data. Data obtained with a ground-based microwave radiometer in Beijing from January 1, 2010 to December 31, 2011 around the date of liquid nitrogen calibration show that the correlation between the observed brightness temperatures and the forward computed brightness temperatures is better after correction, especially at 28 and 30 GHz. The “jumping” problem in the observational data for the brightness temperature is eliminated after correction and the time continuity of the observational data and its consistency with the forward calculated data based on the NCEP-FNL dataset are improved. The proposed correction scheme can be used both for real-time data quality control and to improve the accuracy of historical datasets obtained with poorly calibrated microwave radiometers or radiometers working in polluted environments.
基金supported by the National Key R&D Program of China(2019YFD1100300)the Fellowship of China Postdoctoral Science Foundation(2020M681105)the State Key Laboratory of Urban Water Resource and Environment,Harbin Institute of Technology(No.2021TS23).
文摘The process-based water system models have been transitioning from single-functional to integrated multi-objective and multi-functional since the worldwide digital upgrade of urban water system management.The proliferation of model complexity results in more significant uncertainty and computational requirements.However,conventional model calibration methods are insufficient in dealing with extensive computational time and limited monitoring samples.Here we introduce a novel machine learning system designed to expedite parameter optimization with limited data and boost efficiency in parameter search.MLPS,termed the machine learning parallel system for fast parameter search of integrated process-based models,aims to enhance both the performance and efficiency of the integrated model by ensuring its comprehensiveness,accuracy,and stability.MLPS was constructed upon the concept of model surrogation t algorithm optimization using Ant Colony Optimization(ACO)coupled with Long Short-Term Memory(LSTM).The optimization results of the Integrated sewer network and urban river model demonstrate that the average relative percentage difference of the predicted river pollutant concentrations increases from 1.1 to 6.0,and the average absolute percent bias decreases from 124.3%to 8.8%.The model outputs closely align with the monitoring data,and parameter calibration time is reduced by 89.94%.MLPS enables the efficient optimization of integrated process-based models,facilitating the application of highly precise complex models in environmental management.The design of MLPS also presents valuable insights for optimizing complex models in other fields.
基金financial support from the Chang Jiang Scholars Program(51073047)the National Natural Science Foundation of China(51773049)+5 种基金the China Aerospace Science and Technology Corporation-Harbin Institute of Technology Joint Center for Technology Innovation Fund(HIT15-1A01)the Harbin city science and technology projects(2013DB4BP031 and RC2014QN017035)the Fundamental Research Funds for the Central Universities(HIT.OCEF.2021028)the Natural Science Funds of Heilongjiang Province(ZD2019B001)the Heilongjiang Touyan Team(HITTY-20190033)the funds from Chongqing Research Institute of HIT。
文摘Polynary transition-metal layered hydroxides are promising energy materials owing to their unique architecture,impressive theoretical capacities,and adjustable compositions.Regulating the dimensional morphology and active sites/redox states are the keys to electrochemical performance enhancement.Distinguish from the reported mono-metal or binary-metal configurations,a new ternary-metal AlCoNi-LTH is coanchored onto a highly graphitized porous N-doped carbon matrix to develop superior 3D hierarchical microporous functional energy hybrids AlCoNi-LTHs/NAC.The constructed hybrids possess superior structural durability,good electrical conductivity,and rich active sites due to the strong interfacial conjunction and favorable synergistic effect between the doped porous carbon and AlCoNi nanosheets.Consequently,the AlCoNi-LTHs/NAC hybrids demonstrate high conductivity,reasonable specific surface area,and superior specific capacitance,and the assembled hybrid battery-type supercapacitor reveals an ideal energy density of 72.6 Wh kg^(-1)at a power density of 625 W kg^(-1),which is superior to the reported devices.This strategy opens a platform to rationally design polynary transition-metal layered hydroxides and their hybrids for efficient supercapacitors.
基金This study was supported by Yantai Science and Technology Plan Project[Grant No.2018ZHGY088].
文摘This study was designed to investigate the protective effects of Astaxanthin(AST)in rats with diabetes mellitus(DM)induced by streptozotocin.SD rats were divided into control group(n=5,only received normal saline),DM group(n=8)and AST+DM group(n=8;AST:50 mg/kg/day).DM rats were induced by intraperitoneal injection of streptozocin(STZ,65 mg/kg).Blood glucose level and body weight were determined at weeks 0,2,4,6 and 8,respectively.At week 8,kidney function was determined,together with expression of P53 and dynamin-related protein-1(Drp1)by Western blot analysis and immunofluorescence.AST led to increase of body weight in rats with DM.AST+DM group showed a significant decrease in blood glucose level at week 4 compared with DM group(P<0.05).AST improved renal function and significantly reduced expression of P53 and Drp1 in DM rats.In addition,AST can effectively reduce the blood glucose in DM rats,and delayed the pathogenesis of diabetic nephropathy.Such delay mediated by AST may be associated with the downregulation of Drp1 and P53.
基金Project supported by the National Basic Research Program of China(Grant No.2013CB922204)the National Natural Science Foundation of China(Grant Nos.11574115 and 11704146)
文摘Density functional theory(DFT) and time-dependent density functional theory(TDDFT) methods are used to investigate the influences of intramolecular and intermolecular hydrogen bonding on excited-state intramolecular proton transfer(ESIPT) for the 4-N,N-(diethylamino)-2-hydroxybenzaldehyde(DEAHB). The structures of DEAHB and its hydrogenbonded complex in the ground-state and the excited-state are optimized. In addition, the detailed descriptions of frontier molecular orbitals of the DEAHB monomer and DEAHB-DMSO complex are presented. Moreover, the transition density matrix is worked out to gain deeper insight into the orbitals change. It is hoped that the present work not only elaborates different influence mechanisms between intramolecular and intermolecular hydrogen bonding interactions on the ESIPT process for DEAHB, but also may be helpful to design and develop new materials and applications involved DEAHB systems in the future.
基金Supported by Special Project of Dominant Characteristic Agriculture Breeding in Ningxia Hui Autonomous RegionMajor Project of Agriculture in Ningxia Hui Autonomous Region(2012ZDN1001)
文摘In order to promote marker-assisted selection of Tan sheep, the polymorphism of OB gene in zan sheep was detected by sequencing and PCR-RFLP tech- niques. The correlation between polymorphism of OB gene and weight of Tan sheep was analyzed. The results indicated that there was a CT point mutation at locus 253 in exon 3 region of OB gene, but no mutant homozygote was found. The results of chi-square test showed that the frequency of BB and AB genotypes was con- sistent with Hardy-Weinberg equilibrium. AB genotype was the dominant genotype controlling weight of Tan sheep with the genotype frequency of 0.05. According to the results of correlation analysis, the mutation exerted significant effects on weight of Tan sheep at 3-month-old and 6-month-old (P 〈 0.05). Moreover, interac- tions between ~enotvoe and ~ender had no sianificant effect on weight of Tan sheen ( P 〉 0.05 ).
基金Supported by Special Project for Agricultural Breeding of Ningxia(2018NYYZ0401)Agricultural High Quality Development and Ecological Protection Science and Technology Innovation Demonstration Project of Ningxia(NGSB-2020-12)Scientific and Technological Research Program of Special Project for Agricultural Science and Technology Independent Innovation of Ningxia(NKYZZ-G-19-08)。
文摘Tan sheep industry is a characteristic and superior agricultural industry in Ningxia,and it is also an enriching industry that helps in poverty alleviation and increases farmers’income.The local government has been committing to building the"Yanchi Tan Sheep"brand and has made remarkable achievements.In order to explore the resource efficiency and quality of Tan sheep industry,the current situations and advantages of brand development,this paper made an empirical research through field investigations.The research was mainly concentrated on breeding scale,industrial integration,brand building,breeding benefits,and policy support.After a comprehensive evaluation,it came up with the recommendation that the Tan sheep industry should take the high-quality,high-end and green development road.
基金supported by the Open Fund(No.202303 and No.202304)of the Sichuan Province Engineering Technology Research Center of Healthy Human SettlementKey R&D Plan of Sichuan Science and Technology Program(No.2022YFG0138-LH).
文摘This study focused on the effect of glass structures of modern architecture on the indoor thermal environment during summer.In particular,this study examined how solar radiation significantly altered people’s thermal sensations.Laboratory tests on convection–radiation air conditioning systems were conducted,encompassing 12 different scenarios,including diverse indoor open areas,terminal forms,and levels of solar radiation.These tests aimed to explore the physiological and psychological responses of the human body to solar radiation penetrating through windows into the inner room.During the experiments,the participants’subjective thermal sensations and thermal comfort were recorded,along with continuous monitoring of their physiological and environmental parameters.Results showed that solar radiation significantly increased local skin temperature,with a maximum rise of 2.15℃.Operative temperature is a reliable indicator of human skin temperature and thermal sensation vote(TSV).This study established two models that could predict the skin temperature of individuals indoors through operative temperature under conditions without or with solar radiation,and identified sensitive ranges of operative temperature for both models,to be specific,26.32℃to 28.43℃and 28.51℃to 34.11℃,respectively.Furthermore,this study established the relationship between skin temperature and TSV under conditions with and without solar radiation.The results indicate that solar radiation enhances the human body’s adaptability to indoor environmental parameters;a convection–radiation system(FC+RF)could be used to optimize indoor thermal control under solar radiation,achieving more stable environmental temperatures and improved indoor comfort.
基金funded by the Natural Science Foundation of China(Nos.41790442 and 41825018)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA23090402)the State Key Research Development Program of China(No.2017YFD0800501)。
文摘The large-scale implementation of the Gully Stabilization and Land Reclamation(GSLR)project induces various failures of loess slopes due to excavation in Yan'an,China.However,the deformation and failure behavior of these excavated loess slopes have not been fully understood.In this study,field investigation was undertaken for analyzing the distributions and failure features of excavation-induced loess slope failures.It is found that plastic failure mainly occurs in Q_(3) loess layers and brittle failure in Q_(2).To understand the underlying failure mechanism,a series of triaxial shear tests were conducted on intact Q_(3) and Q_(2) loess samples that with different water contents,namely natural water content(natural),dry side of the natural value(drying 5%),and wet side(wetting 5%).The characteristics of stress-strain curves and failure modes of the samples were analyzed.Results show that the stress-strain curves of Q_(2) samples are dominated by strain-softening characteristics,while Q_(3) samples mainly exhibit strain-harden features except in the drying state.Correspondingly,shear failures of Q_(3) specimens are mainly caused by shear crack planes(single,X or V-shaped).For Q_(2) loess,the dominance of tensile cracks is observed on the surface of damaged specimens.These disclose the different failure modes of excavated slopes located in different strata,that is,the arc sliding failure of Q_(3) loess slopes and the stepped tensile failure of Q_(2) loess slopes,and are helpful in the design and management of the ongoing GSLR projects in the Loess Plateau.