Here we report iron(Fe) isotopic data of three pure Fe solution standards(IRMM-014, GSB Fe, and NIST3126a) and five widely used geological reference materials(RMs) from the United States Geological Survey and Geologic...Here we report iron(Fe) isotopic data of three pure Fe solution standards(IRMM-014, GSB Fe, and NIST3126a) and five widely used geological reference materials(RMs) from the United States Geological Survey and Geological Survey of Japan obtained on a Neptune Plus multi-collector–inductively coupled plasma–mass spectrometer(MC-ICP-MS) in our laboratory over the past 3 years. The instrumental mass bias was corrected by three independent methods: sample-standard bracketing(SSB),Ni doping + SSB, and ^(57)Fe–^(58)Fe double spike + SSB.Measurements reveal that both the Ni doping and double spike methods helped calibrate short-term fluctuations in mass bias. Collectively, almost all measurements of RMs yielded δ^(56)Fe within ± 0.05 of recommended values,provided that each sample was measured four times on MC-ICP-MS. For the first time, new recommended values for NIST SRM3126a are reported(δ^(56)Fe = 0.363 ± 0.006,2SE, 95% CI; and δ^(57)Fe = 0.534 ± 0.010, 2SE).展开更多
Coordinated vehicle-to-grid(V2G)control strategies can sustain essential loads of an energy system during islanding,thereby increasing resilience.In this context,this paper investigates the resilience enhancement bene...Coordinated vehicle-to-grid(V2G)control strategies can sustain essential loads of an energy system during islanding,thereby increasing resilience.In this context,this paper investigates the resilience enhancement benefits of smart V2G control,the value of electric vehicle(EV)owner cooperation on system resilience,as well as the complementary effects of PV and EV interaction in an urban multi-energy microgrid(MEMG).By using a rolling horizon approach to optimize day-ahead operation of the MEMG and subsequently dispatching EVs,uncertainties in outage start time,EV arrival/departure times,and initial state of charge(SOC)are mitigated.Results show that smart V2G control can provide a substantial essential load curtailment reduction compared to a non-EV scenario,meanwhile,non-coordinated grid-to-vehicle(G2V)operation was shown to slightly burden the system with a slight increase in non-essential load curtailment.Investigations into the influence of EV cooperation on resilience showed that a high percentage of system-prioritized(SP)EVs could help greatly further reduce essential load curtailment compared to individual-prioritized(IP)EVs.Finally,the complementary benefits of smart V2G control and PV were demonstrated,showing a reduction in both PV and essential load curtailments with increasing numbers of EVs.Overall,the application of smart V2G control,especially with cooperation of EV owners,can drive significant resilience enhancement during islanding,while further benefits can be obtained through having a sufficient number of EVs to utilize high PV penetration.展开更多
The aim of this research was to evaluate doxorubicin(DOX)-loaded zein in situ gels,a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection.In vitro relea...The aim of this research was to evaluate doxorubicin(DOX)-loaded zein in situ gels,a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection.In vitro release of DOX-loaded zein was investigated and the pharmacokinetics,biodistribution and therapeutic efficacy of these DOX-loaded zein formulations were investigated using BAI B/c nude tumor-bearing mice.In vitro release of DOX from the gels extended up to 7 days.Efficient accumulation of DOX in the tumor with lower drug concentration in blood and normal organs was obtained resulting in effective inhibition of tumor growth and fewer off-target side effects.In conclusion,a DOX-loaded in situ gel was developed with sustained release,enhanced anti-cancer efficacy for colorectal cancer in vivo,and especially with reduced off-target side effects.展开更多
Introduction:Sediment and nutrient retention have significant impacts on agricultural productivity and water quality.Obvious changes of climate and land-use have deeply affected freshwater ecosystem services in the la...Introduction:Sediment and nutrient retention have significant impacts on agricultural productivity and water quality.Obvious changes of climate and land-use have deeply affected freshwater ecosystem services in the last several decades.Nevertheless,it is unclear what the differences are in the impact of climate and land-use changes on freshwater ecosystem services.Outcomes:The impacts of climate and land-use change on sediment and nutrient retention(two essential freshwater ecosystem services)were evaluated with the help of the Integrated Valuation of Environmental Services and Tradeoffs(InVEST)model.The results from the study area suggest a decreasing trend in sediment and nutrient retention from 1995 to 2015 when climate and land-use were changed simultaneously.A decreasing trend in sediment retention and an increasing trend in nutrient retention were presented under scenario A(climate change from 1995 to 2015 with land-use unchanged),while the sediment exported and nutrient retention exhibited a decreasing trend except sediment retained under scenario B(land-use change from 1995 to 2015 with unchanged climate).Rainfall erosivity and soil erodibility were more sensitive to the output of sediment retention,while retention efficiency produced more of an effect on nutrient retention.Discussion and Conclusion:Climate change played a dominant role in the change in sediment retention,while land-use change had a more significant effect on nutrient retention change than climate change.The results of this study provide explicitinformation for land-use managers to reduce the negative effects associated with sediment and nutrient retention.展开更多
As the leading party of the engineering talents cultivation,the colleges and universities not only need to solve the problem for the benefits of teachers who provide the daily management to the students in the enterpr...As the leading party of the engineering talents cultivation,the colleges and universities not only need to solve the problem for the benefits of teachers who provide the daily management to the students in the enterprises, but also consider the safety problems of students who participates the Excellent Program.At the same time。展开更多
Over the years,colleges and universities have been implementing innovative talent training. It is a very important and significant work that how to explore and investigate the training strategy of young university tea...Over the years,colleges and universities have been implementing innovative talent training. It is a very important and significant work that how to explore and investigate the training strategy of young university teachers from the perspective of innovation education.展开更多
The primary cause of it is many college teachers are lack of innovation consciousness and innovation ability,especially for the experienced teachers who have the entrenched thoughts about their teaching ideas.Those ol...The primary cause of it is many college teachers are lack of innovation consciousness and innovation ability,especially for the experienced teachers who have the entrenched thoughts about their teaching ideas.Those old teachers are used to the rote teaching,so it is very difficult to imagine the improvement of student innovation and consciousness and abilities under the old educational pattern.展开更多
Colleges and enterprise should jointly appoint the talent training objectives and standards.Excellent engineers cultivated by the school-enterprise cooperation must meet the needs of business and industries,in additio...Colleges and enterprise should jointly appoint the talent training objectives and standards.Excellent engineers cultivated by the school-enterprise cooperation must meet the needs of business and industries,in addition,schools and enterprises can realize operation and implementation of personnel training objectives.When colleges set the goals,they should consider the teaching staffs and teaching conditions,etc.And when the companies set goals and standards,they must consider on approving the types of talents from the perspective of social demands for engineering talents.展开更多
Since the distinctive innovative, practical features of 'Outstanding Engineers Training Plan'(OETP), the college teachers’ engineering practice ability has to be put forward to higher requirements. However, t...Since the distinctive innovative, practical features of 'Outstanding Engineers Training Plan'(OETP), the college teachers’ engineering practice ability has to be put forward to higher requirements. However, the young teachers consist of the underlying practitioners of the OETP in colleges who are lacking in experiences in engineering practice.展开更多
The 'Outstanding Engineers Training Plan'(OETP) aims to promote the development of higher engineering education constantly. Since the distinctive innovative, practical features of OETP, the college teachers’ ...The 'Outstanding Engineers Training Plan'(OETP) aims to promote the development of higher engineering education constantly. Since the distinctive innovative, practical features of OETP, the college teachers’ engineering practice ability has to be put forward to higher requirements.展开更多
基金supported by the National Natural Science Foundation of China(41473016)the State Key Laboratory of Geological Processes and Mineral Resources
文摘Here we report iron(Fe) isotopic data of three pure Fe solution standards(IRMM-014, GSB Fe, and NIST3126a) and five widely used geological reference materials(RMs) from the United States Geological Survey and Geological Survey of Japan obtained on a Neptune Plus multi-collector–inductively coupled plasma–mass spectrometer(MC-ICP-MS) in our laboratory over the past 3 years. The instrumental mass bias was corrected by three independent methods: sample-standard bracketing(SSB),Ni doping + SSB, and ^(57)Fe–^(58)Fe double spike + SSB.Measurements reveal that both the Ni doping and double spike methods helped calibrate short-term fluctuations in mass bias. Collectively, almost all measurements of RMs yielded δ^(56)Fe within ± 0.05 of recommended values,provided that each sample was measured four times on MC-ICP-MS. For the first time, new recommended values for NIST SRM3126a are reported(δ^(56)Fe = 0.363 ± 0.006,2SE, 95% CI; and δ^(57)Fe = 0.534 ± 0.010, 2SE).
基金supported by the UK Engineering and Physical Sciences Research Council (EP/L015471/1EP/R045518/1).
文摘Coordinated vehicle-to-grid(V2G)control strategies can sustain essential loads of an energy system during islanding,thereby increasing resilience.In this context,this paper investigates the resilience enhancement benefits of smart V2G control,the value of electric vehicle(EV)owner cooperation on system resilience,as well as the complementary effects of PV and EV interaction in an urban multi-energy microgrid(MEMG).By using a rolling horizon approach to optimize day-ahead operation of the MEMG and subsequently dispatching EVs,uncertainties in outage start time,EV arrival/departure times,and initial state of charge(SOC)are mitigated.Results show that smart V2G control can provide a substantial essential load curtailment reduction compared to a non-EV scenario,meanwhile,non-coordinated grid-to-vehicle(G2V)operation was shown to slightly burden the system with a slight increase in non-essential load curtailment.Investigations into the influence of EV cooperation on resilience showed that a high percentage of system-prioritized(SP)EVs could help greatly further reduce essential load curtailment compared to individual-prioritized(IP)EVs.Finally,the complementary benefits of smart V2G control and PV were demonstrated,showing a reduction in both PV and essential load curtailments with increasing numbers of EVs.Overall,the application of smart V2G control,especially with cooperation of EV owners,can drive significant resilience enhancement during islanding,while further benefits can be obtained through having a sufficient number of EVs to utilize high PV penetration.
基金This study was supported by the Natural Science Foundation of China(30801444)the Natural Science Foundation of Hebei Province(H2012208020)the Hebei University of Science and Technology Discipline Construction Office and the State Key Laboratory Breeding Base-Hebei Key Laboratory of Molecular Chemistry For Drug。
文摘The aim of this research was to evaluate doxorubicin(DOX)-loaded zein in situ gels,a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection.In vitro release of DOX-loaded zein was investigated and the pharmacokinetics,biodistribution and therapeutic efficacy of these DOX-loaded zein formulations were investigated using BAI B/c nude tumor-bearing mice.In vitro release of DOX from the gels extended up to 7 days.Efficient accumulation of DOX in the tumor with lower drug concentration in blood and normal organs was obtained resulting in effective inhibition of tumor growth and fewer off-target side effects.In conclusion,a DOX-loaded in situ gel was developed with sustained release,enhanced anti-cancer efficacy for colorectal cancer in vivo,and especially with reduced off-target side effects.
基金This work was supported by the Humanity and Social Science Youth foundation of the Ministry of Education[18YJCZH042].
文摘Introduction:Sediment and nutrient retention have significant impacts on agricultural productivity and water quality.Obvious changes of climate and land-use have deeply affected freshwater ecosystem services in the last several decades.Nevertheless,it is unclear what the differences are in the impact of climate and land-use changes on freshwater ecosystem services.Outcomes:The impacts of climate and land-use change on sediment and nutrient retention(two essential freshwater ecosystem services)were evaluated with the help of the Integrated Valuation of Environmental Services and Tradeoffs(InVEST)model.The results from the study area suggest a decreasing trend in sediment and nutrient retention from 1995 to 2015 when climate and land-use were changed simultaneously.A decreasing trend in sediment retention and an increasing trend in nutrient retention were presented under scenario A(climate change from 1995 to 2015 with land-use unchanged),while the sediment exported and nutrient retention exhibited a decreasing trend except sediment retained under scenario B(land-use change from 1995 to 2015 with unchanged climate).Rainfall erosivity and soil erodibility were more sensitive to the output of sediment retention,while retention efficiency produced more of an effect on nutrient retention.Discussion and Conclusion:Climate change played a dominant role in the change in sediment retention,while land-use change had a more significant effect on nutrient retention change than climate change.The results of this study provide explicitinformation for land-use managers to reduce the negative effects associated with sediment and nutrient retention.
基金financially supported by Educational Reform Project of Hangzhou Dianzi University. (Grant NO.YB201720)
文摘As the leading party of the engineering talents cultivation,the colleges and universities not only need to solve the problem for the benefits of teachers who provide the daily management to the students in the enterprises, but also consider the safety problems of students who participates the Excellent Program.At the same time。
基金financially supported by Educational Reform Project of Hangzhou Dianzi University.(Grant NO.YB201720)
文摘Over the years,colleges and universities have been implementing innovative talent training. It is a very important and significant work that how to explore and investigate the training strategy of young university teachers from the perspective of innovation education.
基金financially supported by Educational Reform Project of Hangzhou Dianzi University.(Grant NO.YB201720)
文摘The primary cause of it is many college teachers are lack of innovation consciousness and innovation ability,especially for the experienced teachers who have the entrenched thoughts about their teaching ideas.Those old teachers are used to the rote teaching,so it is very difficult to imagine the improvement of student innovation and consciousness and abilities under the old educational pattern.
基金financially supported by EducationalReform Project of Hangzhou Dianzi University. (GrantNO.YB201720)
文摘Colleges and enterprise should jointly appoint the talent training objectives and standards.Excellent engineers cultivated by the school-enterprise cooperation must meet the needs of business and industries,in addition,schools and enterprises can realize operation and implementation of personnel training objectives.When colleges set the goals,they should consider the teaching staffs and teaching conditions,etc.And when the companies set goals and standards,they must consider on approving the types of talents from the perspective of social demands for engineering talents.
文摘Since the distinctive innovative, practical features of 'Outstanding Engineers Training Plan'(OETP), the college teachers’ engineering practice ability has to be put forward to higher requirements. However, the young teachers consist of the underlying practitioners of the OETP in colleges who are lacking in experiences in engineering practice.
文摘The 'Outstanding Engineers Training Plan'(OETP) aims to promote the development of higher engineering education constantly. Since the distinctive innovative, practical features of OETP, the college teachers’ engineering practice ability has to be put forward to higher requirements.