Large scale digital beamforming(LS-DBFs)are widely used in satellite communications for spectrum reuse and transmission enhancement.SRAM-FPGAs are a popular option for software defined satellite platforms due to their...Large scale digital beamforming(LS-DBFs)are widely used in satellite communications for spectrum reuse and transmission enhancement.SRAM-FPGAs are a popular option for software defined satellite platforms due to their rich computation resources and high flexibility.However,they are sensitive to soft errors,which limit their application in space.This paper discusses the application of coding based fault tolerance schemes for the protection of LS-DBFs on software defined payloads.Since multiple FPGAs are usually needed to support the whole LS-DBFs system,different decomposition schemes are compared in terms of resource efficiency and reliability when the coding based scheme is applied to protect the DBFs on a FPGA.Theoretical analysis and hardware experiments shows that resource efficiency and reliability are a pair of contradictory requirements for decomposition schemes.The protection with vertical decomposition could improve the reliability by 96%with 1.5x redundancy.And the protection with horizontal decomposition could improve the reliability by 85%with 1.2 x redundancy.展开更多
Pseudorabies(PR)is a devastating viral disease which leads to fatal encephalitis and respiratory disorders in pigs.Commercial gE-deleted live pseudorabies virus(PRV)vaccine has been widely used to control this disease...Pseudorabies(PR)is a devastating viral disease which leads to fatal encephalitis and respiratory disorders in pigs.Commercial gE-deleted live pseudorabies virus(PRV)vaccine has been widely used to control this disease in China.However,the new-emerging variants of PRV compromises the protection provided by current vaccines and lead to the outbreak of PR in vaccinated pig herds.Several killed and live vaccine candidates based on current PRV variants have been reported to be effective to control the disease.A subunit vaccine based on gB protein,one major PRV glycoprotein which elicits strong humoral and cellular immune responses,however,was never evaluated for protection against the current circulating PRV variants.In this study,full-length PRV gB protein was successfully expressed in baculovirus/insect cells in the soluble format and was tested on 3-week-old piglets as a subunit vaccine.Compared with unvaccinated pigs,the gB-vaccinated pigs developed specific antibody-mediated responses and were protected from the virulent PRV HN1201 challenge.All vaccinated pigs survived without showing any PRV-specific respiratory and neurological signs,but all unvaccinated pigs died within 7 days after HN1201 challenge.Hence,this novel gB-based vaccine could be applied as an effective subunit vaccine to control PRV variant in China.展开更多
基金supported in part by the National Natural Science Foundation of China(61501321,61620106001)in part by the Generic Technology Projects of the 13th Fiveyear Plan。
文摘Large scale digital beamforming(LS-DBFs)are widely used in satellite communications for spectrum reuse and transmission enhancement.SRAM-FPGAs are a popular option for software defined satellite platforms due to their rich computation resources and high flexibility.However,they are sensitive to soft errors,which limit their application in space.This paper discusses the application of coding based fault tolerance schemes for the protection of LS-DBFs on software defined payloads.Since multiple FPGAs are usually needed to support the whole LS-DBFs system,different decomposition schemes are compared in terms of resource efficiency and reliability when the coding based scheme is applied to protect the DBFs on a FPGA.Theoretical analysis and hardware experiments shows that resource efficiency and reliability are a pair of contradictory requirements for decomposition schemes.The protection with vertical decomposition could improve the reliability by 96%with 1.5x redundancy.And the protection with horizontal decomposition could improve the reliability by 85%with 1.2 x redundancy.
基金Major Science and Technology Program in Henan Province(131100110200)Innovation Scientists and Technicians Troop Construction Projects of Henan Province(142101510001)the Science and Technology Innovation team in Henan Province(C20130005).
文摘Pseudorabies(PR)is a devastating viral disease which leads to fatal encephalitis and respiratory disorders in pigs.Commercial gE-deleted live pseudorabies virus(PRV)vaccine has been widely used to control this disease in China.However,the new-emerging variants of PRV compromises the protection provided by current vaccines and lead to the outbreak of PR in vaccinated pig herds.Several killed and live vaccine candidates based on current PRV variants have been reported to be effective to control the disease.A subunit vaccine based on gB protein,one major PRV glycoprotein which elicits strong humoral and cellular immune responses,however,was never evaluated for protection against the current circulating PRV variants.In this study,full-length PRV gB protein was successfully expressed in baculovirus/insect cells in the soluble format and was tested on 3-week-old piglets as a subunit vaccine.Compared with unvaccinated pigs,the gB-vaccinated pigs developed specific antibody-mediated responses and were protected from the virulent PRV HN1201 challenge.All vaccinated pigs survived without showing any PRV-specific respiratory and neurological signs,but all unvaccinated pigs died within 7 days after HN1201 challenge.Hence,this novel gB-based vaccine could be applied as an effective subunit vaccine to control PRV variant in China.