To the Editor:Primary Sjögren’s syndrome(pSS)is a multi-systemic autoimmune disease characterized by the exocrine gland(mainly salivary and lacrimal glands)involvement,leading to xerostomia and xerophthalmia.[1]...To the Editor:Primary Sjögren’s syndrome(pSS)is a multi-systemic autoimmune disease characterized by the exocrine gland(mainly salivary and lacrimal glands)involvement,leading to xerostomia and xerophthalmia.[1]The course of pSS is relatively slow,but patients with pSS had higher risk of overall cancer,including malignant lymphoma(ML).[2]It is widely known that all-cause mortality rates were not increased in pSS patients as compared with healthy controls.Nonetheless,secondary lymphoproliferative disease was an important cause of excess mortality.展开更多
基金National Natural Science Foundation of China and by the Beijing Sci-Tech Program(No.Z191100006619114)Natural Science Foundation of China(No.81701607)Peking University People’s Hospital Scientific Research Development Funds(No.RDZH2022-03)
文摘To the Editor:Primary Sjögren’s syndrome(pSS)is a multi-systemic autoimmune disease characterized by the exocrine gland(mainly salivary and lacrimal glands)involvement,leading to xerostomia and xerophthalmia.[1]The course of pSS is relatively slow,but patients with pSS had higher risk of overall cancer,including malignant lymphoma(ML).[2]It is widely known that all-cause mortality rates were not increased in pSS patients as compared with healthy controls.Nonetheless,secondary lymphoproliferative disease was an important cause of excess mortality.
