Chinese idioms are the essence of the Chinese language, the crystallization of human wisdom and the important cartier of national culture. Through the structure, content and meaning of Chinese idioms, we can see vario...Chinese idioms are the essence of the Chinese language, the crystallization of human wisdom and the important cartier of national culture. Through the structure, content and meaning of Chinese idioms, we can see various forms of the history and culture of the Han nationality. Observe national culture through the structure, content, meaning of Chinese idioms, namely the phenomenon of the linguistic phenomenon and culture phenomenon, we focus on elaborating Chinese idioms and cultural relationship between a Chinese idiom and Chinese culture.展开更多
Main observation and conclusion Alkoxy radical-mediated carbon-carbon bond cleavages have emerged as a powerful strategy to complement traditional ionic-type transformations.However,carbon-carbon cleavage reaction tri...Main observation and conclusion Alkoxy radical-mediated carbon-carbon bond cleavages have emerged as a powerful strategy to complement traditional ionic-type transformations.However,carbon-carbon cleavage reaction triggered by alkoxy radical intermediate derived from the combination of alkyl radical and dioxygen,is scarce and underdeveloped.Herein,we report alkoxy radical,which was generated from alkyl radical and dioxygen,mediated selective cleavage of unstrained carbon-carbon bond for the oxysulfonylation of 1,1-disubstituted alkenes,providing facile access to a variety of valuableβ-keto sulfones.Mechanistic experiments indicated alkoxy radical intermediate that underwent subsequent regioselectiveβ-scission might be involved in the reaction and preliminary computational studies were conducted to provide a detailed explanation on the regioselectivity of the C-C bond cleavage.Notably,the strategy was successfully applied for constructing uneasily obtained architecturally intriguing molecules.展开更多
文摘Chinese idioms are the essence of the Chinese language, the crystallization of human wisdom and the important cartier of national culture. Through the structure, content and meaning of Chinese idioms, we can see various forms of the history and culture of the Han nationality. Observe national culture through the structure, content, meaning of Chinese idioms, namely the phenomenon of the linguistic phenomenon and culture phenomenon, we focus on elaborating Chinese idioms and cultural relationship between a Chinese idiom and Chinese culture.
基金Fund of Luzhou Government and Southwest Medical University(Nos.2019LZXNYDJ28,2018LZXNYD-ZK33,2018LZXNYD-ZK39)the Open Project of Central Nervous System Drug Key Laboratory of Sichuan Province(No.200023-01SZ)the research fund of Southwest Medical University(Nos.2017-ZRZD-020 and 2017-ZRQN-031).
文摘Main observation and conclusion Alkoxy radical-mediated carbon-carbon bond cleavages have emerged as a powerful strategy to complement traditional ionic-type transformations.However,carbon-carbon cleavage reaction triggered by alkoxy radical intermediate derived from the combination of alkyl radical and dioxygen,is scarce and underdeveloped.Herein,we report alkoxy radical,which was generated from alkyl radical and dioxygen,mediated selective cleavage of unstrained carbon-carbon bond for the oxysulfonylation of 1,1-disubstituted alkenes,providing facile access to a variety of valuableβ-keto sulfones.Mechanistic experiments indicated alkoxy radical intermediate that underwent subsequent regioselectiveβ-scission might be involved in the reaction and preliminary computational studies were conducted to provide a detailed explanation on the regioselectivity of the C-C bond cleavage.Notably,the strategy was successfully applied for constructing uneasily obtained architecturally intriguing molecules.
