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幽门螺杆菌感染与胃癌中PRC2和H3K27me3的表达关系 被引量:7
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作者 张宁 曾智 +3 位作者 阎丽萍 杨珂 孙庆文 黄鹏 《中国肿瘤临床》 CAS CSCD 北大核心 2018年第13期667-672,共6页
目的:研究幽门螺杆菌(Helicobacter pylori,HP)感染对胃癌组织中多梳抑制复合物2(polycomb repressive complex 2,PRC2)和组蛋白H3K27me3表达的影响,探索HP感染在胃癌发生过程中的作用。方法:利用快速尿素酶检测、Giemsa染色和PCR方法... 目的:研究幽门螺杆菌(Helicobacter pylori,HP)感染对胃癌组织中多梳抑制复合物2(polycomb repressive complex 2,PRC2)和组蛋白H3K27me3表达的影响,探索HP感染在胃癌发生过程中的作用。方法:利用快速尿素酶检测、Giemsa染色和PCR方法检测复旦大学附属上海市第五人民医院2014年1月至2017年10月行胃癌手术的84例患者HP感染情况,应用免疫组织化学法检测胃癌和癌旁组织PRC2和H3K27me3蛋白的表达,分析两者表达与HP感染之间的相关性。结果:3种方法检测HP感染率分别为70.24%、61.90%和76.19%。PRC2家族成员果蝇zeste基因增强子同源物2(enhancer of zeste homolog 2,EZH2)、SUZ12、EED和H3K27me3蛋白在胃癌组织中的阳性表达率分别为79.76%(67/84)、77.38%(65/84)、40.48%(34/84)和69.05%(58/84),均显著高于癌旁组织(22.62%、34.52%、8.33%和14.29%,P<0.05)。临床资料分析表明,EZH2和H3K27me3蛋白在胃癌中的表达与淋巴结转移呈正相关。在HP阳性胃癌组织中,EZH2、SUZ12、EED和H3K27me3蛋白阳性表达率分别为89.06%(57/64)、84.38%(54/64)、46.88%(30/64)和82.81%(53/64),均显著高于HP阴性胃癌组织(50.00%、55.00%、20.00%和25.00%,P<0.05)。结论:HP感染与胃癌组织中PRC2和H3K27me3蛋白表达上调相关。 展开更多
关键词 幽门螺杆菌 多梳抑制复合物2 果蝇zeste基因增强子同源物2 H3K27me3 胃癌
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Evaluation and Forecasting of Wind Energy Investment Risk along the Belt and Road Based on a Novel Hybrid Intelligent Model 被引量:1
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作者 liping yan Wei-Chiang Hong 《Computer Modeling in Engineering & Sciences》 SCIE EI 2021年第9期1069-1102,共34页
The timely and effective investment risk assessment and forecasting are of great significance to ensure the investment safety and sustainable development of wind energy along the Belt and Road.In order to obtain the s... The timely and effective investment risk assessment and forecasting are of great significance to ensure the investment safety and sustainable development of wind energy along the Belt and Road.In order to obtain the scientific and real-time forecasting result,this paper constructs a novel hybrid intelligent model based on improved cloud model combined with GRA-TOPSIS and MBA-WLSSVM.Firstly,the factors influencing investment risk of wind energy along the Belt and Road are identified fromthree dimensions:endogenous risk,exogenous risk and process risk.Through the fuzzy threshold method,the final input index system is selected.Secondly,the risk evaluation method based on improved cloud model andGRA-TOPSIS is proposed.Thirdly,a modern intelligent model based on MBA-WLSSVMis designed.In modified bat algorithm(MBA),tent chaotic map is utilized to improve the basic bat algorithm,while weighted least squares support vector machine(WLSSVM)adopts wavelet kernel function to replace the traditional radial basis function to complete the model improvement.Finally,an example is given to verify the scientificity and accuracy of themodel,which is helpful for investors tomake fast and effective investment risk forecasting of wind energy along the Belt and Road.The example analysis proves that the proposedmodel can provide reference and basis for investment corpus to formulate the investment strategy in wind energy along the Belt and Road. 展开更多
关键词 The belt and road wind power industry investment risk evaluation improved cloud model GRA TOPSIS WLSSVM MBA
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康复阶梯图护理对脑卒中患者依从性及效果观察 被引量:1
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作者 吕勤 李熠 +4 位作者 吴文英 王和强 言丽萍 张建丽 林燕颜 《心电图杂志(电子版)》 2019年第1期191-192,共2页
目的探讨康复阶梯图护理对脑卒中患者依从性及效果。方法选择2014年12月-2018年12月我院接收治疗的脑卒中患者总共60例作为本次的研究对象,并按照随机的方法分为两组,即研究组(n=30)与对照组(n=30);其中对照组使用常规的护理方式,研究... 目的探讨康复阶梯图护理对脑卒中患者依从性及效果。方法选择2014年12月-2018年12月我院接收治疗的脑卒中患者总共60例作为本次的研究对象,并按照随机的方法分为两组,即研究组(n=30)与对照组(n=30);其中对照组使用常规的护理方式,研究组使用康复阶梯图的护理方式;观察并比较两组的依从程度以及护理的效果。结果研究组的依从率是100.00%,对照组的依从率是83.33%,研究组显著高于对照组(P<0.05);研究组在护理后的CSS评分显著低于对照组,同时FMA评分显著高于对照组(P<0.05)。结论在对脑卒中患者的护理过程中,结合使用康复阶梯图这种方法可以比较有效地提高患者的依从性,护理的效果也非常理想,在临床治疗中可以广泛使用。 展开更多
关键词 康复阶梯图 脑卒中 依从性 护理
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An Adaptive Padding Correlation Filter With Group Feature Fusion for Robust Visual Tracking
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作者 Zihang Feng liping yan +1 位作者 Yuanqing Xia Bo Xiao 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2022年第10期1845-1860,共16页
In recent visual tracking research,correlation filter(CF)based trackers become popular because of their high speed and considerable accuracy.Previous methods mainly work on the extension of features and the solution o... In recent visual tracking research,correlation filter(CF)based trackers become popular because of their high speed and considerable accuracy.Previous methods mainly work on the extension of features and the solution of the boundary effect to learn a better correlation filter.However,the related studies are insufficient.By exploring the potential of trackers in these two aspects,a novel adaptive padding correlation filter(APCF)with feature group fusion is proposed for robust visual tracking in this paper based on the popular context-aware tracking framework.In the tracker,three feature groups are fused by use of the weighted sum of the normalized response maps,to alleviate the risk of drift caused by the extreme change of single feature.Moreover,to improve the adaptive ability of padding for the filter training of different object shapes,the best padding is selected from the preset pool according to tracking precision over the whole video,where tracking precision is predicted according to the prediction model trained by use of the sequence features of the first several frames.The sequence features include three traditional features and eight newly constructed features.Extensive experiments demonstrate that the proposed tracker is superior to most state-of-the-art correlation filter based trackers and has a stable improvement compared to the basic trackers. 展开更多
关键词 Adaptive padding context information correlation filter(CF) feature group fusion robust visual tracking
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Development of Strategic Industrial Clusters in Guangdong Higher Vocational Colleges based on the"Double High Plan" 被引量:1
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作者 liping yan yanzhi Peng 《Journal of Contemporary Educational Research》 2021年第6期8-13,共6页
This article analyzed the ten strategic pillar industry clusters and the ten strategic emerging industry clusters which were confirmed and announced by Guangdong Province in May 2020 in addition to the 14 professional... This article analyzed the ten strategic pillar industry clusters and the ten strategic emerging industry clusters which were confirmed and announced by Guangdong Province in May 2020 in addition to the 14 professional groups of schools in Guangdong Province which were shortlisted in the"Double High Plan."With comparison and analysis,the degree of coincidence between the professional groups of higher vocational colleges and strategic industrial clusters in Guangdong Province which covered most of the industrial clusters was relatively high.The higher vocational colleges that were shortlisted in the"Double High Plan"still required dynamic adjustments in the construction of professional groups to achieve an allrounded integration of the supply of talents and industrial demands. 展开更多
关键词 Double High Plan Professional group Industrial clusters
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Study on Tissue Culture and Rapid Propagation of Tilia amurensis
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作者 Yinhua WANG Yuguang KONG +2 位作者 Yingjun HE liping yan Dejun WU 《Agricultural Biotechnology》 CAS 2022年第3期18-21,28,共5页
To explore the establishment of a tissue culture and rapid propagation system of Tilia amurensis,the effects of basic medium and concentrations and ratios of plant growth regulators on tissue culture and rapid propaga... To explore the establishment of a tissue culture and rapid propagation system of Tilia amurensis,the effects of basic medium and concentrations and ratios of plant growth regulators on tissue culture and rapid propagation of T.amurensis were studied.The results showed that 1/2 MS medium was the most suitable proliferation medium,and the proliferation coefficient could reach 13.5 after adding 0.05 mg/L 6-BA and 0.03 mg/L IBA;MS medium was the most suitable medium for strong plantlets and rooting,and the best medium for strong plantlets was MS+0.1 mg/L 6-BA+0.1 mg/L IBA+0.03 mg/L GA_(3),with which the average plantlet height reached 5.15 cm;and the best rooting medium was MS+1.0 mg/L6-BA+0.05 mg/L NAA,with which the rooting rate was 93.3%and the number of roots was 5.7 roots. 展开更多
关键词 Tilia amurensis Tissue culture Medium for strong plantlets Medium for rooting Vegetative propagation Rapid propagation
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Research on the Influencing Factors of Environmental Information Disclosure in Thermal Power Enterprises
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作者 liping yan 《经济管理学刊(中英文版)》 2016年第1期19-27,共9页
关键词 环境信息 影响因素 多重线性回归分析 企业 社会责任 年度报告 热力 中国
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根据路况条件、卡车速度以及负载水平对中国卡车运输震动水平进行测量研究
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作者 Ran Zhou liping yan +1 位作者 Baiguo Li Jing Xie 《绿色包装》 2016年第1期79-79,共1页
通过卡车速度、路况条件以及负载水平三个方面,测量卡车的运输震动水平。卡车组由一台正常装载卡车和一台装有钢板弹簧悬架的超载卡车组成。卡车速度试验被分成3组:0–30 km/h,31–60 km/h以及61–90 km/h.交通道路由高速公路、主干道(A... 通过卡车速度、路况条件以及负载水平三个方面,测量卡车的运输震动水平。卡车组由一台正常装载卡车和一台装有钢板弹簧悬架的超载卡车组成。卡车速度试验被分成3组:0–30 km/h,31–60 km/h以及61–90 km/h.交通道路由高速公路、主干道(ARs)、二级公路(SRs)以及三级公路(TRs)组成。结果显示了运输震动水平随着卡车速度增加而增加;三级公路(TRs)导致了最高的运输震动水平,其次是二级公路(SRs),再其次是主干道(ARs)、最后是高速公路。功率谱密度峰值出现在3或3.5 Hz.。超载可能抑制了运输振动水平,尤其是在低速的情况下。 展开更多
关键词 卡车运输 动水 速度 路况 测量 负载 中国 钢板弹簧悬架
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Gut microbial community structure and function of Przewalski’s horses varied across reintroduced sites in China
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作者 liping TANG liping yan +9 位作者 Huiping JIA Yu XIONG Xinping MA Hongjun CHU Zhicheng SUN Liang WANG Mubalake SHALITANATI Kai LI Defu HU Dong ZHANG 《Integrative Zoology》 SCIE CSCD 2023年第6期1027-1040,共14页
Host-associated microbiota can significantly impact host fitness.Therefore,naturally occurring variations in microbiota may influence the health and persistence of their hosts.This finding is particularly important in... Host-associated microbiota can significantly impact host fitness.Therefore,naturally occurring variations in microbiota may influence the health and persistence of their hosts.This finding is particularly important in reintroduced animals,as they typically experience habitat changes during translocations.However,little is known about how microbiomes are altered in response to conservation translocation.Here,we accessed the gut microbiome of Przewalski’s horse(Equus przewalskii)populations in China from three nature reserves(i.e.Xinjiang Kalamaili Nature Reserve,KNR;Dunhuang Xihu National Nature Reserve,DXNNR;and Anxi Extreme-arid Desert Nature Reserve,AENR)using 16s rRNA gene and metagenome sequencing.The results showed that the microbial composition and function differed significantly across locations,while a subset of core taxa was consistently present in most of the samples.The abundance of genes encoding microbe-produced enzymes involved in the metabolism of carbohydrates,especially for glycoside hydrolases,was significantly higher in open-spaced KNR populations than in more confined AENR individuals.This study offers detailed and significant differential characters related to the microbial community and metabolic pathways in various reintroduced sites of Przewalski’s horse,which might provide a basis for future microecological and conservation research on endangered reintroduced animals. 展开更多
关键词 16s rRNA gene METAGENOME microbial variation REINTRODUCTION
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Metagenomics reveals contrasting energy utilization efficiencies of captive and wild camels(Camelus ferus) 被引量:2
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作者 liping yan liping TANG +7 位作者 Zhichao ZHOU Wei LU Bo WANG Zhicheng SUN Xue JIANG Defu HU Junqing LI Dong ZHANG 《Integrative Zoology》 SCIE CSCD 2022年第3期333-345,共13页
Captive conditions can affect the symbiotic microbiome of animals.In this study,we compared the structural and functional differences of the gastrointestinal microbiomes of wild Bactrian camels(Camelus ferus)between w... Captive conditions can affect the symbiotic microbiome of animals.In this study,we compared the structural and functional differences of the gastrointestinal microbiomes of wild Bactrian camels(Camelus ferus)between wild and captive populations,as well as their different host energy utilization performances through metagenomics.The results showed that wild-living camels harbored more microbial taxa related to the production of volatile fatty acids,fewer methanogens,and fewer genes encoding enzymes involved in methanogenesis,leading to higher energy utilization efficiency compared to that of captive-living camels.These findings suggest that the wild-living camel fecal microbiome demonstrates a series of adaptive characteristics that enable the host to adjust to a relatively barren field environment.Our study provides novel insights into the mechanisms of wildlife adaptations to habitats from the perspective of the microbiome. 展开更多
关键词 ADAPTABILITY energy utilization gastrointestinal microbiome METAGENOMICS wild and captive wild Bactrian camel
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Preliminary analysis of chemical reaction under the radiation of electromagnetic wave 被引量:1
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作者 Kama Huang Ning Liu +1 位作者 Changjun Liu liping yan 《Chinese Science Bulletin》 SCIE EI CAS 2000年第19期1821-1824,共4页
Microwave can be used to accelerate chemical reaction and improve the rate of production. Does microwave only act as a heating factor? Do there exist any specific effects? These questions are still holding a violent c... Microwave can be used to accelerate chemical reaction and improve the rate of production. Does microwave only act as a heating factor? Do there exist any specific effects? These questions are still holding a violent controversy. Here we will choose the Belousov-Zhabotinsky reaction, which is sensitive to surrounding effects, to study the influence of microwave on chemical reactions. Visible changes of periods have been observed. It appeares that there could have been specific effects of microwave. 展开更多
关键词 MICROWAVE ELECTROMAGNETIC wave Belousov-Zhabotinsky reaction specific effects.
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