目的探讨腹腔镜下前列腺癌根治术后切缘阳性的相关危险因素。方法回顾性分析2014年9月至2019年12月在苏州大学附属第一医院泌尿外科行腹腔镜下前列腺癌根治术的499例患者资料,其中术后切缘阳性79例,切缘阴性420例。采用单因素分析患者...目的探讨腹腔镜下前列腺癌根治术后切缘阳性的相关危险因素。方法回顾性分析2014年9月至2019年12月在苏州大学附属第一医院泌尿外科行腹腔镜下前列腺癌根治术的499例患者资料,其中术后切缘阳性79例,切缘阴性420例。采用单因素分析患者年龄、术前PSA(≤20 ng/ml vs>20 ng/ml)、前列腺体积、穿刺阳性针数、肿瘤临床分期(T_(1~2b) vs T_(2c~4))、术后Gleason评分(<8分vs≥8分)、淋巴结转移情况对切缘阳性的影响,采用多因素Logistic回归分析确定切缘阳性的独立危险因素。结果单因素分析表明,穿刺阳性针数、肿瘤临床分期(T_(1~2b) vs T_(2c~4))及Gleason评分(<8分vs≥8分)是手术切缘阳性的相关因素,P值均<0.001。多因素Logistic回归分析显示穿刺阳性针数、肿瘤临床分期(T_(1~2b) vs T_(2c~4))是切缘阳性的独立危险因素,P值均<0.001。结论肿瘤临床分期、穿刺阳性针数可作为独立预测切缘阳性的有效预测指标。临床分期T_(2c~4)患者的切缘阳性率显著增高;穿刺阳性针数越多,术后切缘阳性发生率越高。展开更多
Cross-range scaling plays an important role in the inverse synthetic aperture radar(ISAR) imaging. Many of the published cross-range scaling algorithms are based on the fast Fourier transformation(FFT). However, the F...Cross-range scaling plays an important role in the inverse synthetic aperture radar(ISAR) imaging. Many of the published cross-range scaling algorithms are based on the fast Fourier transformation(FFT). However, the FFT technique is resolution limited, so that the FFT-based algorithms will fail in the rotation velocity(RV) estimation of the slow rotation target. In this paper,we propose an accurate cross-range scaling algorithm based on the multiple signal classification(MUSIC) method. We first select some range bins with the mono-component linear frequency modulated(LFM) signal model. Then, we dechirp the signal of each selected range bin into the form of sinusoidal signal, and utilize the super-resolution MUSIC technique to accurately estimate the frequency. After processing all the range bins, a linear relationship related to the RV can be obtained. Eventually, the ISAR image can be scaled. The proposal can precisely estimate the small RV of the slow rotation target with low computational complexity. Furthermore, the proposal can also be used in the case of cross-range scaling for the sparse aperture data. Experimental results with the simulated and raw data validate the superiority of the novel method.展开更多
[Objective]The paper was to understand the resistance of commonly used clinical antibiotics to avian Escherichia coli and the inhibition of lactobacillus against pathogenic E.coli.[Method]The strain was isolated and i...[Objective]The paper was to understand the resistance of commonly used clinical antibiotics to avian Escherichia coli and the inhibition of lactobacillus against pathogenic E.coli.[Method]The strain was isolated and identified by SS medium culture,microscope examination,PCR amplification and biochemical test,and the sensitivity of avian E.coli to eight antibiotics was determined by disk diffusion method.Twelve strains of avian E.coli and one strain of lactobacillus were divided into five group using in vitro liquid culture method,namely simultaneous mixed culture group of lactobacillus and E.coli,first colonization group of E.coli,first colonization group of lactobacillus,E.coli control group and lactobacillus control group,for competitive inhibition test between E.coli and lactobacillus.[Result]Totally 34 strains with similar characteristics to E.coli strains were preliminarily screened;the target band amplified by PCR was 293 bp,which was consistent with the expected size.The isolated strain could decompose maltose,sucrose,lactose,glucose,arabinose,mannitol and sorbitol;the nitrate reduction test was positive,while citrate and V-P test was negative,consistent with the biochemical characteristics of E.coli.The resistance rate of the isolates to cefalexin and tylosin was over 65%,and that to enrofloxacin and doxycycline was up to 50%;the isolates were more sensitive to apramycin,tilmicosin,neomycin and colistin,and the total resistance rate was below 15%.The inhibitory effects of mixed culture of lactobacillus and E.coli against E.coli was better than first colonization of lactobacillus at 24 h;the inhibitory effects of first colonization of lactobacillus against E.coli was better than that of mixed culture of lactobacillus and E.coli at 36 h;the inhibitory effects of mixed culture of lactobacillus and E.coli against E.coli was the best at 48 h.[Conclusion]The isolated strains of E.coli were generally resistant to eight commonly used antibiotics.Lactobacillus could inhibit the growth of avian E.coli in vitro,and first colonization of lactobacillus received the best effort.展开更多
文摘目的探讨腹腔镜下前列腺癌根治术后切缘阳性的相关危险因素。方法回顾性分析2014年9月至2019年12月在苏州大学附属第一医院泌尿外科行腹腔镜下前列腺癌根治术的499例患者资料,其中术后切缘阳性79例,切缘阴性420例。采用单因素分析患者年龄、术前PSA(≤20 ng/ml vs>20 ng/ml)、前列腺体积、穿刺阳性针数、肿瘤临床分期(T_(1~2b) vs T_(2c~4))、术后Gleason评分(<8分vs≥8分)、淋巴结转移情况对切缘阳性的影响,采用多因素Logistic回归分析确定切缘阳性的独立危险因素。结果单因素分析表明,穿刺阳性针数、肿瘤临床分期(T_(1~2b) vs T_(2c~4))及Gleason评分(<8分vs≥8分)是手术切缘阳性的相关因素,P值均<0.001。多因素Logistic回归分析显示穿刺阳性针数、肿瘤临床分期(T_(1~2b) vs T_(2c~4))是切缘阳性的独立危险因素,P值均<0.001。结论肿瘤临床分期、穿刺阳性针数可作为独立预测切缘阳性的有效预测指标。临床分期T_(2c~4)患者的切缘阳性率显著增高;穿刺阳性针数越多,术后切缘阳性发生率越高。
基金supported by the National Natural Science Foundation of China (61871146,61622107)the China Scholarship Council(201906120113)。
文摘Cross-range scaling plays an important role in the inverse synthetic aperture radar(ISAR) imaging. Many of the published cross-range scaling algorithms are based on the fast Fourier transformation(FFT). However, the FFT technique is resolution limited, so that the FFT-based algorithms will fail in the rotation velocity(RV) estimation of the slow rotation target. In this paper,we propose an accurate cross-range scaling algorithm based on the multiple signal classification(MUSIC) method. We first select some range bins with the mono-component linear frequency modulated(LFM) signal model. Then, we dechirp the signal of each selected range bin into the form of sinusoidal signal, and utilize the super-resolution MUSIC technique to accurately estimate the frequency. After processing all the range bins, a linear relationship related to the RV can be obtained. Eventually, the ISAR image can be scaled. The proposal can precisely estimate the small RV of the slow rotation target with low computational complexity. Furthermore, the proposal can also be used in the case of cross-range scaling for the sparse aperture data. Experimental results with the simulated and raw data validate the superiority of the novel method.
基金Major Science and Technology Innovation Project of Liaoning Province"Feed Quality and Safety Control and Low Protein Feed Project"(2019JH1/10200002).
文摘[Objective]The paper was to understand the resistance of commonly used clinical antibiotics to avian Escherichia coli and the inhibition of lactobacillus against pathogenic E.coli.[Method]The strain was isolated and identified by SS medium culture,microscope examination,PCR amplification and biochemical test,and the sensitivity of avian E.coli to eight antibiotics was determined by disk diffusion method.Twelve strains of avian E.coli and one strain of lactobacillus were divided into five group using in vitro liquid culture method,namely simultaneous mixed culture group of lactobacillus and E.coli,first colonization group of E.coli,first colonization group of lactobacillus,E.coli control group and lactobacillus control group,for competitive inhibition test between E.coli and lactobacillus.[Result]Totally 34 strains with similar characteristics to E.coli strains were preliminarily screened;the target band amplified by PCR was 293 bp,which was consistent with the expected size.The isolated strain could decompose maltose,sucrose,lactose,glucose,arabinose,mannitol and sorbitol;the nitrate reduction test was positive,while citrate and V-P test was negative,consistent with the biochemical characteristics of E.coli.The resistance rate of the isolates to cefalexin and tylosin was over 65%,and that to enrofloxacin and doxycycline was up to 50%;the isolates were more sensitive to apramycin,tilmicosin,neomycin and colistin,and the total resistance rate was below 15%.The inhibitory effects of mixed culture of lactobacillus and E.coli against E.coli was better than first colonization of lactobacillus at 24 h;the inhibitory effects of first colonization of lactobacillus against E.coli was better than that of mixed culture of lactobacillus and E.coli at 36 h;the inhibitory effects of mixed culture of lactobacillus and E.coli against E.coli was the best at 48 h.[Conclusion]The isolated strains of E.coli were generally resistant to eight commonly used antibiotics.Lactobacillus could inhibit the growth of avian E.coli in vitro,and first colonization of lactobacillus received the best effort.
