目的探讨奥布卡因凝胶预防鼻内镜术后苏醒期躁动的有效性。方法采用前瞻性研究,选择2019年9月~2020年9月ASAⅠ~Ⅱ级择期全麻鼻内镜手术80例,随机分为奥布卡因组和对照组,每组40例。奥布卡因组术前将2 ml 0.3%盐酸奥布卡因凝胶涂抹气管...目的探讨奥布卡因凝胶预防鼻内镜术后苏醒期躁动的有效性。方法采用前瞻性研究,选择2019年9月~2020年9月ASAⅠ~Ⅱ级择期全麻鼻内镜手术80例,随机分为奥布卡因组和对照组,每组40例。奥布卡因组术前将2 ml 0.3%盐酸奥布卡因凝胶涂抹气管导管套囊及前端15 cm范围内,对照组涂抹等量生理盐水,2组均进行常规麻醉诱导、气管插管。记录2组苏醒期躁动及严重程度,记录术中低血压、心动过缓、高血压、心动过速、体动等不良反应情况。结果奥布卡因组发生苏醒期躁动的比例显著低于对照组[10.0%(4/40)vs.37.5%(15/40),χ^2=8.352,P=0.004],且程度更轻[无、轻度、中度、重度分别为36、4、0、0例vs.25、7、5、3例,Z=-3.051,P=0.002]。奥布卡因组发生术中低血压[22.5%(9/40)vs.47.5%(19/40),χ^2=5.495,P=0.019]及心动过缓[7.5%(3/40)vs.27.5%(11/40),χ^2=5.541,P=0.019]的比例显著低于对照组。结论奥布卡因凝胶可以有效预防鼻内镜术后苏醒期躁动。展开更多
A wind turbine system equipped with a tuned liquid column damper （TLCD） is comprehensively studied via shaking table tests using a 1/13-scaled model. The effects of wind and wave actions are considered by inputting ...A wind turbine system equipped with a tuned liquid column damper （TLCD） is comprehensively studied via shaking table tests using a 1/13-scaled model. The effects of wind and wave actions are considered by inputting response- equivalent accelerations on the shaking table. The test results show that the control effect of the TLCD system is significant in reducing the responses under both wind-wave equivalent loads and ground motions, but obviously varies for different inputs, Further, a blade-hub-tower integrated numerical model for the wind turbine system is established. The model is capable of considering the rotational effect of blades by combining Kane＇s equation with the finite element method. The responses of the wind tower equipped with TLCD devices are numerically obtained and compared to the test results, showing that under both controlled and uncontrolled conditions with and without blades＇ rotation, the corresponding responses exhibit good agreement. This demonstrates that the proposed numerical model performs well in capturing the wind-wave coupled response of the offshore wind turbine systems under control. Both numerical and experimental results show that the TLCD system can significantly reduce the structural response and thus improve the safety and serviceability of the offshore wind turbine tower systems. Additional issues that require further study are discussed.展开更多
文摘目的探讨奥布卡因凝胶预防鼻内镜术后苏醒期躁动的有效性。方法采用前瞻性研究,选择2019年9月~2020年9月ASAⅠ~Ⅱ级择期全麻鼻内镜手术80例,随机分为奥布卡因组和对照组,每组40例。奥布卡因组术前将2 ml 0.3%盐酸奥布卡因凝胶涂抹气管导管套囊及前端15 cm范围内,对照组涂抹等量生理盐水,2组均进行常规麻醉诱导、气管插管。记录2组苏醒期躁动及严重程度,记录术中低血压、心动过缓、高血压、心动过速、体动等不良反应情况。结果奥布卡因组发生苏醒期躁动的比例显著低于对照组[10.0%(4/40)vs.37.5%(15/40),χ^2=8.352,P=0.004],且程度更轻[无、轻度、中度、重度分别为36、4、0、0例vs.25、7、5、3例,Z=-3.051,P=0.002]。奥布卡因组发生术中低血压[22.5%(9/40)vs.47.5%(19/40),χ^2=5.495,P=0.019]及心动过缓[7.5%(3/40)vs.27.5%(11/40),χ^2=5.541,P=0.019]的比例显著低于对照组。结论奥布卡因凝胶可以有效预防鼻内镜术后苏醒期躁动。
基金National Natural Science Foundation of China Under Grant No.11172210National Hi-Tech Development Plan(863 Plan)Under Grant No.2008AA05Z413+2 种基金the Fundamental Fund for Central Universitiesthe Shuguang Program of Shanghai Citythe State Key Laboratory of Disaster Reduction in Civil Engineering Under Grant Nos.SLDRCE14-A-06 and SLDRCE14-B-17
文摘A wind turbine system equipped with a tuned liquid column damper （TLCD） is comprehensively studied via shaking table tests using a 1/13-scaled model. The effects of wind and wave actions are considered by inputting response- equivalent accelerations on the shaking table. The test results show that the control effect of the TLCD system is significant in reducing the responses under both wind-wave equivalent loads and ground motions, but obviously varies for different inputs, Further, a blade-hub-tower integrated numerical model for the wind turbine system is established. The model is capable of considering the rotational effect of blades by combining Kane＇s equation with the finite element method. The responses of the wind tower equipped with TLCD devices are numerically obtained and compared to the test results, showing that under both controlled and uncontrolled conditions with and without blades＇ rotation, the corresponding responses exhibit good agreement. This demonstrates that the proposed numerical model performs well in capturing the wind-wave coupled response of the offshore wind turbine systems under control. Both numerical and experimental results show that the TLCD system can significantly reduce the structural response and thus improve the safety and serviceability of the offshore wind turbine tower systems. Additional issues that require further study are discussed.
