Two novel metal-organic frameworks(MOFs),JLU-MOF130([In(NH2−BDC)(Imi)(1H−Imi)]·DMF·H2O,NH2−H2BDC=2-aminobenzene-1,4-dicarboxylic acid,1H−Imi=1H-imidazole,DMF=N,N-dimethylformamide)and JLU-MOF131([In(1,4-NDC)...Two novel metal-organic frameworks(MOFs),JLU-MOF130([In(NH2−BDC)(Imi)(1H−Imi)]·DMF·H2O,NH2−H2BDC=2-aminobenzene-1,4-dicarboxylic acid,1H−Imi=1H-imidazole,DMF=N,N-dimethylformamide)and JLU-MOF131([In(1,4-NDC)(Imi)(1H−Imi)]·DMF0.5,1,4-H_(2)NDC=1,4-naphthalene-dicarboxylic acid),were synthesized.JLU-MOF130 features a three-dimensional(3D)architecture with a neb topology.JLU-MOF131 is characterized by a two-dimensional(2D)structure with an sql topology.JLU-MOF130 has excellent fluorescence detection performance towards Fe^(3+),2,4-dinitrophenol(2,4-DNP),and 2,4,6-trinitrophenol(TNP),but the fluorescence detection performance of JLU-MOF131 is further improved by converting NH2−H2BDC to more conjugated 1,4-H_(2)NDC.The Stern-Volmer(SV)quenching constant(KSV)values of JLU-MOF130 sensing 2,4-DNP,TNP,and Fe^(3+)are 5.24×10^(4),4.44×10^(4),and 4.73×10^(3) L/mol,respectively.The corresponding limit of detection(LOD)values are 1.17,1.36,and 14.59µmol/L.The KSV values for JLU-MOF131 are 1.26×10^(5),9.02×10^(4),and 8.48×103 L/mol,and the corresponding LOD values are 0.35,0.42,and 3.60µmol/L,respectively.interestingly,the emission wavelengths of the two MOFs obviously shift as the fluorescence emission intensities decrease upon the addition of 2,4-DNP and TNP,which can be applied in selective detection.展开更多
目的探讨内质网应激蛋白在大鼠正畸模型中的表达变化及其临床意义。方法30只SD大鼠按照随机数字表法分为对照组和模型组,模型组大鼠上颌磨牙间固定镍钛拉簧,建立实验性正畸模型,对照组大鼠不做处理。两组大鼠分别在加力12、24、48、72 ...目的探讨内质网应激蛋白在大鼠正畸模型中的表达变化及其临床意义。方法30只SD大鼠按照随机数字表法分为对照组和模型组,模型组大鼠上颌磨牙间固定镍钛拉簧,建立实验性正畸模型,对照组大鼠不做处理。两组大鼠分别在加力12、24、48、72 h处死大鼠,采用蛋白质印迹法(Western blot)分析分析两组大鼠牙周组织内质网应激蛋白C/EBP同源蛋白(CHOP)和葡萄糖调节蛋白78(GRP78)蛋白表达水平;采用酶联免疫吸附试验(ELISA)法检测牙周组织丙二醛(MDA)、GSH和超氧化物歧化酶(SOD)表达水平;采用末端脱氧核苷酸转移酶介导的dUTP缺口末端标记(TUNEL)染色技术分析两组大鼠牙周组织细胞凋亡比例;组间和组间计量资料比较采用t检验。结果对照组大鼠12、24、48、72 h MDA水平[(4.91±0.73)、(5.01±0.78)、(5.10±0.62)、(4.89±0.82)mmol/L]明显低于模型组12、24、48、72 h MDA水平[(6.43±0.81)、(8.41±0.89)、(14.22±1.99)、(7.45±1.09)mmol/L],差异有统计学意义(t=2.091、3.412、6.119、3.816,P<0.05)。对照组大鼠12、24、48、72 h SOD水平[(208.32±23.87)、(201.43±18.29)、(198.33±21.43)、(203.12±20.19)U/mg]明显高于模型组12、24、48、72 h SOD水平[(187.09±18.43)、(158.39±19.39)、(120.58±20.09)、(165.32±17.83)U/mg],差异有统计学意义(t=3.109、3.891、6.819、4.192,P<0.05)。对照组大鼠12、24、48、72 h GRP78水平(1.23±0.12、1.18±0.09、1.25±0.12、1.17±0.11)明显低于模型组12、24、48、72 h GRP78水平(1.57±0.10、1.78±0.09、2.19±0.11、1.70±0.09),差异有统计学意义(t=1.664、2.290、2.891、2.099,P<0.05)。对照组大鼠12、24、48、72 h CHOP水平(0.89±0.09、0.80±0.11、0.85±0.10、0.87±0.10)明显低于模型组12、24、48、72 h CHOP水平(1.04±0.11、1.26±0.10、1.64±0.12、1.30±0.11),差异有统计学意义(t=1.948、2.591、3.663、2.984,P<0.05)。对照组大鼠12、24、48、72 h TUNEL阳性率水平[(3.11±0.43)%、(3.49±0.32)%、(3.22±0.41)%、(3.62±0.43)%]明显低于模型组12、24、48、72 h TUNEL阳性率水平[(6.44±0.89)%、(9.39±1.95)%、(14.32±3.19)%、(10.32±2.10)%],差异有统计学意义(t=2.008、2.784、3.722、3.012,P<0.05)。结论在实验性正畸24 h,牙周组织氧化应激反应明显增加,内质网应激蛋白表达增加,内质网应激诱导的细胞凋亡水平明显增加,随着时间延长,牙周组织氧化应激、内质网应激和细胞凋亡比例明显下降,牙周组织逐渐适应加力刺激。展开更多
We differentiated the effects of Cu films deposited on single crystalline a-,r-,and c-plane sapphire substrates upon graphene films synthesized with atmospheric pressure chemical vapor deposition(CVD).The data illustr...We differentiated the effects of Cu films deposited on single crystalline a-,r-,and c-plane sapphire substrates upon graphene films synthesized with atmospheric pressure chemical vapor deposition(CVD).The data illustrate that the realization of high-crystalline Cu film is dependent not only on the crystallinity of underlying substrate,but also on the symmetric match of crystallographic geometry between metal film and substrate.We also systematically investigated the effects of PMMA removal on the Raman ID/IG and IG/I2D values of transferred graphene.The results reveal that different PMMA removal methods do not alter the ID/IG values;instead,the residue of PMMA increases the IG/I2D values and the thermal decomposition of PMMA leads to higher IG/I2D values than the removal of PMMA with acetone.The effects of PMMA removal on variations of the Raman spectra are also discussed.展开更多
A luminescent Ag-based metal-organic framework(compound 1)has been synthesized and its structure has been characterized.Compound 1 was fabricated using the Ag+and bbimb2−ligands and manifestes a rare LON topology.Comp...A luminescent Ag-based metal-organic framework(compound 1)has been synthesized and its structure has been characterized.Compound 1 was fabricated using the Ag+and bbimb2−ligands and manifestes a rare LON topology.Compound 1 is selective not only in detecting traces of Fe^(3+)and 2,4,6-trinitrophenol(TNP)via luminescence quenching,but also demonstrates high selectivity in the presence of other competitors.Compound 1’s K sv values towards Fe^(3+)can reach as high as 9.3×l0^(3) L/mol,which is higher than those of several other MOF materials.It is also a recyclable luminous sensor with the potential to be utilized for detecting TNP.Hence,based on its characteristics,compound 1 can be regarded as a prospective luminescence sensor for detecting Fe^(3+)and TNP.展开更多
Metal-organic frameworks(MOFs) are a class of porous inorganic-organic hybrid materials, which are constructed from diverse inorganic building units and multi-functional organic ligands. Highly ordered pore structures...Metal-organic frameworks(MOFs) are a class of porous inorganic-organic hybrid materials, which are constructed from diverse inorganic building units and multi-functional organic ligands. Highly ordered pore structures and tailored functionalization have made MOF materials potential for applications in many fields. Among various MOF materials, 3p-block metal(Al, Ga, and In)-based MOFs exhibit higher chemical stability than divalent transition metal-based MOFs due to their higher valence. In this review, Al-MOFs and In-MOFs were mainly discussed from the perspective of categories of inorganic building blocks, coordination types, and numbers of organic ligands. This review will give intuitive guidance to the design and synthesis of novel 3p-block metal-based MOFs with potential applications.展开更多
基金the National Natural Science Foundation of China(Nos.22171100,22288101)and the“111”Project of China(No.B17020).
文摘Two novel metal-organic frameworks(MOFs),JLU-MOF130([In(NH2−BDC)(Imi)(1H−Imi)]·DMF·H2O,NH2−H2BDC=2-aminobenzene-1,4-dicarboxylic acid,1H−Imi=1H-imidazole,DMF=N,N-dimethylformamide)and JLU-MOF131([In(1,4-NDC)(Imi)(1H−Imi)]·DMF0.5,1,4-H_(2)NDC=1,4-naphthalene-dicarboxylic acid),were synthesized.JLU-MOF130 features a three-dimensional(3D)architecture with a neb topology.JLU-MOF131 is characterized by a two-dimensional(2D)structure with an sql topology.JLU-MOF130 has excellent fluorescence detection performance towards Fe^(3+),2,4-dinitrophenol(2,4-DNP),and 2,4,6-trinitrophenol(TNP),but the fluorescence detection performance of JLU-MOF131 is further improved by converting NH2−H2BDC to more conjugated 1,4-H_(2)NDC.The Stern-Volmer(SV)quenching constant(KSV)values of JLU-MOF130 sensing 2,4-DNP,TNP,and Fe^(3+)are 5.24×10^(4),4.44×10^(4),and 4.73×10^(3) L/mol,respectively.The corresponding limit of detection(LOD)values are 1.17,1.36,and 14.59µmol/L.The KSV values for JLU-MOF131 are 1.26×10^(5),9.02×10^(4),and 8.48×103 L/mol,and the corresponding LOD values are 0.35,0.42,and 3.60µmol/L,respectively.interestingly,the emission wavelengths of the two MOFs obviously shift as the fluorescence emission intensities decrease upon the addition of 2,4-DNP and TNP,which can be applied in selective detection.
文摘目的探讨内质网应激蛋白在大鼠正畸模型中的表达变化及其临床意义。方法30只SD大鼠按照随机数字表法分为对照组和模型组,模型组大鼠上颌磨牙间固定镍钛拉簧,建立实验性正畸模型,对照组大鼠不做处理。两组大鼠分别在加力12、24、48、72 h处死大鼠,采用蛋白质印迹法(Western blot)分析分析两组大鼠牙周组织内质网应激蛋白C/EBP同源蛋白(CHOP)和葡萄糖调节蛋白78(GRP78)蛋白表达水平;采用酶联免疫吸附试验(ELISA)法检测牙周组织丙二醛(MDA)、GSH和超氧化物歧化酶(SOD)表达水平;采用末端脱氧核苷酸转移酶介导的dUTP缺口末端标记(TUNEL)染色技术分析两组大鼠牙周组织细胞凋亡比例;组间和组间计量资料比较采用t检验。结果对照组大鼠12、24、48、72 h MDA水平[(4.91±0.73)、(5.01±0.78)、(5.10±0.62)、(4.89±0.82)mmol/L]明显低于模型组12、24、48、72 h MDA水平[(6.43±0.81)、(8.41±0.89)、(14.22±1.99)、(7.45±1.09)mmol/L],差异有统计学意义(t=2.091、3.412、6.119、3.816,P<0.05)。对照组大鼠12、24、48、72 h SOD水平[(208.32±23.87)、(201.43±18.29)、(198.33±21.43)、(203.12±20.19)U/mg]明显高于模型组12、24、48、72 h SOD水平[(187.09±18.43)、(158.39±19.39)、(120.58±20.09)、(165.32±17.83)U/mg],差异有统计学意义(t=3.109、3.891、6.819、4.192,P<0.05)。对照组大鼠12、24、48、72 h GRP78水平(1.23±0.12、1.18±0.09、1.25±0.12、1.17±0.11)明显低于模型组12、24、48、72 h GRP78水平(1.57±0.10、1.78±0.09、2.19±0.11、1.70±0.09),差异有统计学意义(t=1.664、2.290、2.891、2.099,P<0.05)。对照组大鼠12、24、48、72 h CHOP水平(0.89±0.09、0.80±0.11、0.85±0.10、0.87±0.10)明显低于模型组12、24、48、72 h CHOP水平(1.04±0.11、1.26±0.10、1.64±0.12、1.30±0.11),差异有统计学意义(t=1.948、2.591、3.663、2.984,P<0.05)。对照组大鼠12、24、48、72 h TUNEL阳性率水平[(3.11±0.43)%、(3.49±0.32)%、(3.22±0.41)%、(3.62±0.43)%]明显低于模型组12、24、48、72 h TUNEL阳性率水平[(6.44±0.89)%、(9.39±1.95)%、(14.32±3.19)%、(10.32±2.10)%],差异有统计学意义(t=2.008、2.784、3.722、3.012,P<0.05)。结论在实验性正畸24 h,牙周组织氧化应激反应明显增加,内质网应激蛋白表达增加,内质网应激诱导的细胞凋亡水平明显增加,随着时间延长,牙周组织氧化应激、内质网应激和细胞凋亡比例明显下降,牙周组织逐渐适应加力刺激。
基金supported by the National Basic Research Program of China(2012CB215500)the National Natural Science Foundation of China(51272296)+1 种基金the Natural Science Foundation of Chongqing(CSTC2012jjA50014)Fundamental Research Funds for the Central Universities(CDJZR12225501,CQDXWL-2013-016)
文摘We differentiated the effects of Cu films deposited on single crystalline a-,r-,and c-plane sapphire substrates upon graphene films synthesized with atmospheric pressure chemical vapor deposition(CVD).The data illustrate that the realization of high-crystalline Cu film is dependent not only on the crystallinity of underlying substrate,but also on the symmetric match of crystallographic geometry between metal film and substrate.We also systematically investigated the effects of PMMA removal on the Raman ID/IG and IG/I2D values of transferred graphene.The results reveal that different PMMA removal methods do not alter the ID/IG values;instead,the residue of PMMA increases the IG/I2D values and the thermal decomposition of PMMA leads to higher IG/I2D values than the removal of PMMA with acetone.The effects of PMMA removal on variations of the Raman spectra are also discussed.
基金National Natural Science Foundation of China(No.21901021)Program of Jilin Provincial Science&Technology Department,China(No.20200201242JC)China Postdoctoral Science Foundation(No.2021T140256).
文摘A luminescent Ag-based metal-organic framework(compound 1)has been synthesized and its structure has been characterized.Compound 1 was fabricated using the Ag+and bbimb2−ligands and manifestes a rare LON topology.Compound 1 is selective not only in detecting traces of Fe^(3+)and 2,4,6-trinitrophenol(TNP)via luminescence quenching,but also demonstrates high selectivity in the presence of other competitors.Compound 1’s K sv values towards Fe^(3+)can reach as high as 9.3×l0^(3) L/mol,which is higher than those of several other MOF materials.It is also a recyclable luminous sensor with the potential to be utilized for detecting TNP.Hence,based on its characteristics,compound 1 can be regarded as a prospective luminescence sensor for detecting Fe^(3+)and TNP.
基金This work was supported by the National Natural Science Foundation of China(No. 21771078).
文摘Metal-organic frameworks(MOFs) are a class of porous inorganic-organic hybrid materials, which are constructed from diverse inorganic building units and multi-functional organic ligands. Highly ordered pore structures and tailored functionalization have made MOF materials potential for applications in many fields. Among various MOF materials, 3p-block metal(Al, Ga, and In)-based MOFs exhibit higher chemical stability than divalent transition metal-based MOFs due to their higher valence. In this review, Al-MOFs and In-MOFs were mainly discussed from the perspective of categories of inorganic building blocks, coordination types, and numbers of organic ligands. This review will give intuitive guidance to the design and synthesis of novel 3p-block metal-based MOFs with potential applications.
