In this article, to improve the doubly robust estimator, the nonlinear regression models with missing responses are studied. Based on the covariate balancing propensity score (CBPS), estimators for the regression coef...In this article, to improve the doubly robust estimator, the nonlinear regression models with missing responses are studied. Based on the covariate balancing propensity score (CBPS), estimators for the regression coefficients and the population mean are obtained. It is proved that the proposed estimators are asymptotically normal. In simulation studies, the proposed estimators show improved performance relative to usual augmented inverse probability weighted estimators.展开更多
High-dimensional longitudinal data arise frequently in biomedical and genomic research. It is important to select relevant covariates when the dimension of the parameters diverges as the sample size increases. We cons...High-dimensional longitudinal data arise frequently in biomedical and genomic research. It is important to select relevant covariates when the dimension of the parameters diverges as the sample size increases. We consider the problem of variable selection in high-dimensional linear models with longitudinal data. A new variable selection procedure is proposed using the smooth-threshold generalized estimating equation and quadratic inference functions (SGEE-QIF) to incorporate correlation information. The proposed procedure automatically eliminates inactive predictors by setting the corresponding parameters to be zero, and simultaneously estimates the nonzero regression coefficients by solving the SGEE-QIF. The proposed procedure avoids the convex optimization problem and is flexible and easy to implement. We establish the asymptotic properties in a high-dimensional framework where the number of covariates increases as the number of cluster increases. Extensive Monte Carlo simulation studies are conducted to examine the finite sample performance of the proposed variable selection procedure.展开更多
In this article, we develop a statistical inference technique for the unknown coefficient functions in the varying coeffi- cient model with random effect. A residual-adjusted block empirical likelihood (RABEL) method ...In this article, we develop a statistical inference technique for the unknown coefficient functions in the varying coeffi- cient model with random effect. A residual-adjusted block empirical likelihood (RABEL) method is suggested to inves- tigate the model by taking the within-subject correlation into account. Due to the residual adjustment, the proposed RABEL is asymptotically chi-squared distribution. We illustrate the large sample performance of the proposed method via Monte Carlo simulations and a real data application.展开更多
In this paper, we consider the problem of variable selection and model detection in additive models with longitudinal data. Our approach is based on spline approximation for the components aided by two Smoothly Clippe...In this paper, we consider the problem of variable selection and model detection in additive models with longitudinal data. Our approach is based on spline approximation for the components aided by two Smoothly Clipped Absolute Deviation (SCAD) penalty terms. It can perform model selection (finding both zero and linear components) and estimation simultaneously. With appropriate selection of the tuning parameters, we show that the proposed procedure is consistent in both variable selection and linear components selection. Besides, being theoretically justified, the proposed method is easy to understand and straightforward to implement. Extensive simulation studies as well as a real dataset are used to illustrate the performances.展开更多
When longitudinal data contains outliers, the classical least-squares approach is known to be not robust. To solve this issue, the exponential squared loss (ESL) function with a tuning parameter has been investigated ...When longitudinal data contains outliers, the classical least-squares approach is known to be not robust. To solve this issue, the exponential squared loss (ESL) function with a tuning parameter has been investigated for longitudinal data. However, to our knowledge, there is no paper to investigate the robust estimation procedure against outliers within the framework of mean-covariance regression analysis for longitudinal data using the ESL function. In this paper, we propose a robust estimation approach for the model parameters of the mean and generalized autoregressive parameters with longitudinal data based on the ESL function. The proposed estimators can be shown to be asymptotically normal under certain conditions. Moreover, we develop an iteratively reweighted least squares (IRLS) algorithm to calculate the parameter estimates, and the balance between the robustness and efficiency can be achieved by choosing appropriate data adaptive tuning parameters. Simulation studies and real data analysis are carried out to illustrate the finite sample performance of the proposed approach.展开更多
In this article, we propose a generalized empirical likelihood inference for the parametric component in semiparametric generalized partially linear models with longitudinal data. Based on the extended score vector, a...In this article, we propose a generalized empirical likelihood inference for the parametric component in semiparametric generalized partially linear models with longitudinal data. Based on the extended score vector, a generalized empirical likelihood ratios function is defined, which integrates the within-cluster?correlation meanwhile avoids direct estimating the nuisance parameters in the correlation matrix. We show that the proposed statistics are asymptotically?Chi-squared under some suitable conditions, and hence it can be used to construct the confidence region of parameters. In addition, the maximum empirical likelihood estimates of parameters and the corresponding asymptotic normality are obtained. Simulation studies demonstrate the performance of the proposed method.展开更多
We consider the problem of variable selection for the single-index random effects models with longitudinal data. An automatic variable selection procedure is developed using smooth-threshold. The proposed method share...We consider the problem of variable selection for the single-index random effects models with longitudinal data. An automatic variable selection procedure is developed using smooth-threshold. The proposed method shares some of the desired features of existing variable selection methods: the resulting estimator enjoys the oracle property;the proposed procedure avoids the convex optimization problem and is flexible and easy to implement. Moreover, we use the penalized weighted deviance criterion for a data-driven choice of the tuning parameters. Simulation studies are carried out to assess the performance of our method, and a real dataset is analyzed for further illustration.展开更多
文摘In this article, to improve the doubly robust estimator, the nonlinear regression models with missing responses are studied. Based on the covariate balancing propensity score (CBPS), estimators for the regression coefficients and the population mean are obtained. It is proved that the proposed estimators are asymptotically normal. In simulation studies, the proposed estimators show improved performance relative to usual augmented inverse probability weighted estimators.
文摘High-dimensional longitudinal data arise frequently in biomedical and genomic research. It is important to select relevant covariates when the dimension of the parameters diverges as the sample size increases. We consider the problem of variable selection in high-dimensional linear models with longitudinal data. A new variable selection procedure is proposed using the smooth-threshold generalized estimating equation and quadratic inference functions (SGEE-QIF) to incorporate correlation information. The proposed procedure automatically eliminates inactive predictors by setting the corresponding parameters to be zero, and simultaneously estimates the nonzero regression coefficients by solving the SGEE-QIF. The proposed procedure avoids the convex optimization problem and is flexible and easy to implement. We establish the asymptotic properties in a high-dimensional framework where the number of covariates increases as the number of cluster increases. Extensive Monte Carlo simulation studies are conducted to examine the finite sample performance of the proposed variable selection procedure.
文摘In this article, we develop a statistical inference technique for the unknown coefficient functions in the varying coeffi- cient model with random effect. A residual-adjusted block empirical likelihood (RABEL) method is suggested to inves- tigate the model by taking the within-subject correlation into account. Due to the residual adjustment, the proposed RABEL is asymptotically chi-squared distribution. We illustrate the large sample performance of the proposed method via Monte Carlo simulations and a real data application.
文摘In this paper, we consider the problem of variable selection and model detection in additive models with longitudinal data. Our approach is based on spline approximation for the components aided by two Smoothly Clipped Absolute Deviation (SCAD) penalty terms. It can perform model selection (finding both zero and linear components) and estimation simultaneously. With appropriate selection of the tuning parameters, we show that the proposed procedure is consistent in both variable selection and linear components selection. Besides, being theoretically justified, the proposed method is easy to understand and straightforward to implement. Extensive simulation studies as well as a real dataset are used to illustrate the performances.
文摘When longitudinal data contains outliers, the classical least-squares approach is known to be not robust. To solve this issue, the exponential squared loss (ESL) function with a tuning parameter has been investigated for longitudinal data. However, to our knowledge, there is no paper to investigate the robust estimation procedure against outliers within the framework of mean-covariance regression analysis for longitudinal data using the ESL function. In this paper, we propose a robust estimation approach for the model parameters of the mean and generalized autoregressive parameters with longitudinal data based on the ESL function. The proposed estimators can be shown to be asymptotically normal under certain conditions. Moreover, we develop an iteratively reweighted least squares (IRLS) algorithm to calculate the parameter estimates, and the balance between the robustness and efficiency can be achieved by choosing appropriate data adaptive tuning parameters. Simulation studies and real data analysis are carried out to illustrate the finite sample performance of the proposed approach.
文摘In this article, we propose a generalized empirical likelihood inference for the parametric component in semiparametric generalized partially linear models with longitudinal data. Based on the extended score vector, a generalized empirical likelihood ratios function is defined, which integrates the within-cluster?correlation meanwhile avoids direct estimating the nuisance parameters in the correlation matrix. We show that the proposed statistics are asymptotically?Chi-squared under some suitable conditions, and hence it can be used to construct the confidence region of parameters. In addition, the maximum empirical likelihood estimates of parameters and the corresponding asymptotic normality are obtained. Simulation studies demonstrate the performance of the proposed method.
文摘We consider the problem of variable selection for the single-index random effects models with longitudinal data. An automatic variable selection procedure is developed using smooth-threshold. The proposed method shares some of the desired features of existing variable selection methods: the resulting estimator enjoys the oracle property;the proposed procedure avoids the convex optimization problem and is flexible and easy to implement. Moreover, we use the penalized weighted deviance criterion for a data-driven choice of the tuning parameters. Simulation studies are carried out to assess the performance of our method, and a real dataset is analyzed for further illustration.