[Objectives]To explore the effects of Peikun Pill on blood pressure of healthy adult male rats.[Methods]The duodenum of anesthetized rats was given different doses of Peikun Pills,normal saline was used as a blank con...[Objectives]To explore the effects of Peikun Pill on blood pressure of healthy adult male rats.[Methods]The duodenum of anesthetized rats was given different doses of Peikun Pills,normal saline was used as a blank control group,and captopril was used as a positive western medicine control group.The systolic blood pressure,diastolic blood pressure,mean blood pressure and pulse pressure difference(systolic blood pressure-diastolic blood pressure),and heart rate were measured,myocardial tension time index was calculated,and statistical processing was performed.[Results]Peikun Pills have a significant pressure boosting effect,but have no effect on the myocardial tension time index.Captopril has the effects of lowering blood pressure,slowing down the heart rate and reducing the myocardial tension time index,and significantly increasing the pulse pressure difference.[Conclusions]Peikun Pills can increase blood pressure of rats.Peikun Pills are suitable for women with hypotension accompanied by anemia.However,patients with hypertension are prohibited to use.展开更多
文摘[Objectives]To explore the effects of Peikun Pill on blood pressure of healthy adult male rats.[Methods]The duodenum of anesthetized rats was given different doses of Peikun Pills,normal saline was used as a blank control group,and captopril was used as a positive western medicine control group.The systolic blood pressure,diastolic blood pressure,mean blood pressure and pulse pressure difference(systolic blood pressure-diastolic blood pressure),and heart rate were measured,myocardial tension time index was calculated,and statistical processing was performed.[Results]Peikun Pills have a significant pressure boosting effect,but have no effect on the myocardial tension time index.Captopril has the effects of lowering blood pressure,slowing down the heart rate and reducing the myocardial tension time index,and significantly increasing the pulse pressure difference.[Conclusions]Peikun Pills can increase blood pressure of rats.Peikun Pills are suitable for women with hypotension accompanied by anemia.However,patients with hypertension are prohibited to use.
