In the immune system,antigen-presenting cells,especially dendritic cells,process tumor antigens and present them to anti-tumor CD8+ cytotoxic T cells and CD4+ helper T cells,thereby promoting the proliferation and act...In the immune system,antigen-presenting cells,especially dendritic cells,process tumor antigens and present them to anti-tumor CD8+ cytotoxic T cells and CD4+ helper T cells,thereby promoting the proliferation and activity of these cells to kill tumor cells.展开更多
A 7-year-old girl presented to our out-patient clinic with complaints of abdominal mass and pain with yellowish skin for over 3 months.The patient was also accompanied by clinical manifestations such as nausea and vom...A 7-year-old girl presented to our out-patient clinic with complaints of abdominal mass and pain with yellowish skin for over 3 months.The patient was also accompanied by clinical manifestations such as nausea and vomiting,skin itching and clay-colored stools.She denied any past history of gastrointestinal bleeding or trauma.Examination revealed a non-tender swelling as it moved with breathing(Panel A).展开更多
Plants have developed sophisticated systems to cope with herbivore challenge, including morphological barriers and secondary metabolites to reduce damage. In this study, 550 Gossypium genotypes were evaluated for whit...Plants have developed sophisticated systems to cope with herbivore challenge, including morphological barriers and secondary metabolites to reduce damage. In this study, 550 Gossypium genotypes were evaluated for whitefly(Bemisia tabaci) resistance in five experiments including two in the field and three in the greenhouse, with23 resistant and 19 susceptible genotypes selected.Whitefly-resistance index determination showed that a leaf having a high density of hairs had resistance to whitfly egg/nymph production. Longer leaf hairs were also important for resistance. This study revealed that okra shaped leaves reduced adult whitefly oviposition preference, while glabrous leaves and high hair density helped not only in the reduction of the adults but also decreased oviposition preference. Gossypol was also observed to be involved in the reduction of adult whitefly development and/or survival.展开更多
基金Supported by a grant from the Key Projects of the National Science &Technology Pillar Program during the Twelfth Five-year Plan Period(No.2014BAI09B07)
文摘In the immune system,antigen-presenting cells,especially dendritic cells,process tumor antigens and present them to anti-tumor CD8+ cytotoxic T cells and CD4+ helper T cells,thereby promoting the proliferation and activity of these cells to kill tumor cells.
基金This study was supported by the National Key R&D Program Project(No.2017YFC0909900)Qinghai Science and Technology Department 2022 Science and Technology Plan Projects(Qinghai Research Key Laboratory for Echinococcosis Research)+2 种基金Young and Middle-aged Scientific Research Fund Project of the Affiliated Hospital of Qinghai University(No.ASRF-2021-YB-17)Tsinghua University Institute of Precision Medicine Strategic Project(Nos.2022ZLA005,2022ZLB004)Beijing Natural Science Foundation(No.Z190024).
文摘A 7-year-old girl presented to our out-patient clinic with complaints of abdominal mass and pain with yellowish skin for over 3 months.The patient was also accompanied by clinical manifestations such as nausea and vomiting,skin itching and clay-colored stools.She denied any past history of gastrointestinal bleeding or trauma.Examination revealed a non-tender swelling as it moved with breathing(Panel A).
基金supported by the National Key Research and Development Plan (2016YFD0100203-9)National Natural Science Foundation of China (31371673)National R&D Project of Transgenic Crops of Ministry of Science and Technology of China (2016ZX08010001-006) to Professor Shuangxia Jin
文摘Plants have developed sophisticated systems to cope with herbivore challenge, including morphological barriers and secondary metabolites to reduce damage. In this study, 550 Gossypium genotypes were evaluated for whitefly(Bemisia tabaci) resistance in five experiments including two in the field and three in the greenhouse, with23 resistant and 19 susceptible genotypes selected.Whitefly-resistance index determination showed that a leaf having a high density of hairs had resistance to whitfly egg/nymph production. Longer leaf hairs were also important for resistance. This study revealed that okra shaped leaves reduced adult whitefly oviposition preference, while glabrous leaves and high hair density helped not only in the reduction of the adults but also decreased oviposition preference. Gossypol was also observed to be involved in the reduction of adult whitefly development and/or survival.
