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Reactive uveitis, retinal vasculitis and scleritis as ocular end-stage of Acanthamoeba keratitis: a histological study
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作者 Lei Shi Tobias Hager +6 位作者 Fabian Norbert Fries loay daas Leonard Holbach Carmen Hofmann-Rummelt Elena Zemova Berthold Seitz Nóra Szentmáry 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2019年第12期1966-1971,共6页
We analysed histologically two Acanthamoeba keratitis(AK) eyes with anterior and posterior segment inflammation and blindness. Two enucleated eyes of 2 patients(age 45 and 51y) with AK(PCR of epithelial abrasion posit... We analysed histologically two Acanthamoeba keratitis(AK) eyes with anterior and posterior segment inflammation and blindness. Two enucleated eyes of 2 patients(age 45 and 51y) with AK(PCR of epithelial abrasion positive) were analysed. Histological analysis was performed using hematoxylin-eosin, periodic acid-Schiff and G?m?rimethenamine silver staining. We could not observe Acanthamoeba trophozoites or cysts neither in the cornea nor in other ocular tissues. Meanwhile, we found uveitis, retinal vasculitis and scleritis in these eyes, due to the long-standing, recalcitrant AK. So in this stage of AK, systemic immune suppression may be necessary for a longer time period. 展开更多
关键词 Acanthamoeba keratitis ENUCLEATION UVEITIS retinal vasculitis SCLERITIS
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