针对轴向永磁齿轮电动机(Axial Magnetic Gear Motor,AMGM)整体尺寸偏大导致的转矩密度偏低(≤70 kN·m/m^(3))等缺陷,提出了一种双调制式轴向永磁齿轮电动机(Dual-modulation Axial Magnetic Gear Motor,DAMGM)。采用高速侧及低速...针对轴向永磁齿轮电动机(Axial Magnetic Gear Motor,AMGM)整体尺寸偏大导致的转矩密度偏低(≤70 kN·m/m^(3))等缺陷,提出了一种双调制式轴向永磁齿轮电动机(Dual-modulation Axial Magnetic Gear Motor,DAMGM)。采用高速侧及低速侧两个调磁环对DAMGM低速转子进行调制,且两个调磁环中的非导磁部分均为永磁体,有效提高了低速转子的输出转矩;另外,与现有AMGM相比,将驱动电动机置于DAMGM高速永磁转子内部,减小了整体轴向尺寸,大幅提高了低速转子的转矩密度(150 kN·m/m^(3))。针对现有3D有限元计算时间长、计算机资源浪费严重等问题,给出一种基于圆柱坐标系的DAMGM三维分析方法。根据调磁环的3种边界条件,建立了调制后DAMGM气隙磁场及电磁转矩的数理模型,不仅计算结果准确(与3D有限元相比,平均计算误差≤5%),而且计算时间短(仅为3D有限元的1/10),便于DAMGM不同参数结构的分析、比较与优化。展开更多
BACKGROUND Bladder cancer(BC)is the most common urological tumor.It has a high recur-rence rate,displays tutor heterogeneity,and resists chemotherapy.Furthermore,the long-term survival rate of BC patients has remained...BACKGROUND Bladder cancer(BC)is the most common urological tumor.It has a high recur-rence rate,displays tutor heterogeneity,and resists chemotherapy.Furthermore,the long-term survival rate of BC patients has remained unchanged for decades,which seriously affects the quality of patient survival.To improve the survival rate and prognosis of BC patients,it is necessary to explore the molecular mechanisms of BC development and progression and identify targets for treatment and intervention.Transmembrane 9 superfamily member 1(TM9SF1),also known as MP70 and HMP70,is a member of a family of nine transmembrane superfamily proteins,which was first identified in 1997.TM9SF1 can be expressed in BC,but its biological function and mechanism in BC are not clear.AIM To investigate the biological function and mechanism of TM9SF1 in BC.Overexpression of TM9SF1 increased the in vitro proliferation,migration,and invasion of BC cells by promoting the entry of BC cells into the G2/M phase.Silencing of TM9SF1 inhibited in vitro proliferation,migration,and invasion of BC cells and blocked BC cells in the G1 phase.CONCLUSION TM9SF1 may be an oncogene in BC.展开更多
文摘针对轴向永磁齿轮电动机(Axial Magnetic Gear Motor,AMGM)整体尺寸偏大导致的转矩密度偏低(≤70 kN·m/m^(3))等缺陷,提出了一种双调制式轴向永磁齿轮电动机(Dual-modulation Axial Magnetic Gear Motor,DAMGM)。采用高速侧及低速侧两个调磁环对DAMGM低速转子进行调制,且两个调磁环中的非导磁部分均为永磁体,有效提高了低速转子的输出转矩;另外,与现有AMGM相比,将驱动电动机置于DAMGM高速永磁转子内部,减小了整体轴向尺寸,大幅提高了低速转子的转矩密度(150 kN·m/m^(3))。针对现有3D有限元计算时间长、计算机资源浪费严重等问题,给出一种基于圆柱坐标系的DAMGM三维分析方法。根据调磁环的3种边界条件,建立了调制后DAMGM气隙磁场及电磁转矩的数理模型,不仅计算结果准确(与3D有限元相比,平均计算误差≤5%),而且计算时间短(仅为3D有限元的1/10),便于DAMGM不同参数结构的分析、比较与优化。
基金Supported by National Natural Science Foundation of China,No.82260785.
文摘BACKGROUND Bladder cancer(BC)is the most common urological tumor.It has a high recur-rence rate,displays tutor heterogeneity,and resists chemotherapy.Furthermore,the long-term survival rate of BC patients has remained unchanged for decades,which seriously affects the quality of patient survival.To improve the survival rate and prognosis of BC patients,it is necessary to explore the molecular mechanisms of BC development and progression and identify targets for treatment and intervention.Transmembrane 9 superfamily member 1(TM9SF1),also known as MP70 and HMP70,is a member of a family of nine transmembrane superfamily proteins,which was first identified in 1997.TM9SF1 can be expressed in BC,but its biological function and mechanism in BC are not clear.AIM To investigate the biological function and mechanism of TM9SF1 in BC.Overexpression of TM9SF1 increased the in vitro proliferation,migration,and invasion of BC cells by promoting the entry of BC cells into the G2/M phase.Silencing of TM9SF1 inhibited in vitro proliferation,migration,and invasion of BC cells and blocked BC cells in the G1 phase.CONCLUSION TM9SF1 may be an oncogene in BC.
