Association between uveitis and psoriatic disease: a systematic review and Meta-analysis based on the evidence from cohort studies

AIM: To conduct a systematic review and Meta-analysis to examine the association between uveitis and psoriatic disease, and to evaluate whether one condition predisposes individuals to the other. METHODS: We performed a comprehensive search of Pub Med and EMBASE to identify cohort studies examining the association between uveitis and psoriatic disease [psoriasis and/or psoriatic arthritis(Ps A)]. We used a random-effects model to calculate the pooled relative risks(RRs) adjusted for confounders, along with the 95% confidence intervals(CIs). RESULTS: This Meta-analysis included a total of 6 studies and a maximum of 80 178 648 participants. Compared with non-psoriatic controls, uveitis risk was significantly elevated in patients with psoriasis(RR=1.49;95%CI: 1.08-2.07), and Ps A(RR=3.16;95%CI: 2.16-4.63). Furthermore, pre-existing uveitis was associated with a significantly increased risk of psoriasis(RR=1.62;95%CI: 1.44-1.83), and Ps A(RR=4.44;95%CI: 3.52-5.60).CONCLUSION: The results of this systematic review and Meta-analysis suggest an overall positive bidirectional association between uveitis and psoriatic disease(psoriasis and Ps A), warranting increased awareness among clinicians involved in the management of these two conditions.Therefore, there remains a need for more detailed studies of the possible common pathogenesis of psoriatic disease and uveitis.

高硼/钇合金化提高FeAl基金属间化合物多孔材料的抗氧化性能

利用反应合成法制备高铬(Cr)、硼(B)、钇(Y)复合合金化的B2结构FeAl基金属间化合物多孔材料,通过研究FeAl基多孔材料氧化后的孔结构演变、氧化动力学和氧化膜构型,探讨其高温氧化行为。结果显示,添加高含量合金元素Cr、B和Y后,FeAl多孔材料在600~800℃下氧化增质显著降低。富集在氧化膜表面的B和偏聚在氧化膜与基体界面处的Y共同促进多孔材料表面形成薄且具有优异防护性的结节状α-Al_(2)O_(3)氧化膜。研究表明,引入较高含量的活性元素如B和Y有利于FeAl金属间化合物在较低氧化温度和无预处理的情况下选择性生长单一的α-Al_(2)O_(3)氧化膜。

A dual-switching spin-crossover framework with redox regulation and guest response

A dual-switching spin crossover metal-organic framework(SCO-MOF)[Fe(TPB){Pt^(Ⅱ)(CN)_(4)}]·3iPrOH·4H_(2)O(TPB=1,2,4,5-tetra(pyridin-4-yl)benzene)is developed via the combination of redox-active framework and tunable guests.The reversible structural transformation between[Pt^(Ⅱ)(CN)_(4)]^(2-) and[Pt^(Ⅳ)Br_(2)(CN)_(4)]^(2-)moieties can be manipulated by redox post-synthetic modification(PSM),which results in the change of SCO behaviors from step-wise to one-step.The influences of the oxidative addition of bromides on the ligand field splitting of Fe side are further explored by density functional theory calculations.Besides,the modulation of hysteretic four-/three-step,one-step and four-step SCO behaviors can be achieved by tuning the composition of guest molecules.Therefore,the combination of electronic bistability,redox reaction and guest recognition in a homogeneous lattice provides a utility platform for designing multi-responsive molecule-based materials.

Inclusion of methylviologen dication in a cadmium tetracyanoplatinate host clathrate showing photochromism and photoluminescence modulation

A cadmium tetracyanoplatinate host clathrate,(MV)[Cd_(2){Pt(CN)_(4)}_(3)]·2(H_(2)O)(1),including a methylviologen dication (MV^(2+)) was synthesized,and the crystal structures,photochromic and photoluminescence properties were investigated.In 1,the alternatively parallel stacking between the MV^(2+)dications as electron acceptors in the channels and the electron donors[Pt1(CN)_(4)]^(2-) units in the host frameworks give a unique donor-acceptor (DA) system.Under UV irradiation,the electron transfer between MV^(2+) and[Pt(CN)_(4)]^(2-) ions generates MV^(·+)radicals with a photochromic behavior from pale-yellow to blue.This process occurs through single-crystal-to-single-crystal (SCSC) transformation and obvious structure variation of viologen cations is successfully observed.Moreover,the spectral overlap between the emission bands of 1 and the absorption around 623 nm for the MV^(·+) radicals leads to a modulation of the photoluminescence.

Magnetically recoverable Cu2O/Fe_3O_4 composite photocatalysts:Fabrication and photocatalytic activity

A magnetically separable Cu2O/Fe3O4 magnetic composite photocatalyst was synthesized in large quantities by a fast and simple route. The as-prepared photocatalysts were characterized by scanning electron microscopy （SEM）, transmission electron microscopy （TEM）, X-ray photoelectron spectroscopy （XPS） and X-ray diffraction （XRD）. Furthermore, the Cu2O/Fe3O4 composite photocatalysts were tested using methyl orange （MO） degradation reaction under visible light irradiation （100 mW/cm2） and demonstrated to have a high photocatalytic efficiency toward the decomposition of MO under visible light irradiation with good recyclability.

Reversible on-off switching of spin-crossover behavior via photochemical [2+2] cycloaddition reaction

Herein,we report the first example showing the reversible on-off switching of spin-crossover(SCO)property by solid state photochemical[2+2]reaction.The ultraviolet(UV)light-induced[2+2]cycloaddition reaction of 3-spy ligands in a twodimensional(2D)Hofmann-type framework[Fe(3-spy)_(2){Pd(CN)_(4)}](1,3-spy=3-styrylpyridine),which shows a hysteretic twostep SCO behavior,gives a 3D Hofmann-type framework[Fe(rctt-3-ppcb){Pd(CN)_(4)}](2,rctt-3-ppcb=rctt-1,3-bis(3-pyridyl)-2,4-bis(phenyl)cyclobutane,r=reference group,c=cis and t=trans)accompanied with the disappearing of SCO properties.Moreover,upon heating at 250℃ for 12 h,the rctt-3-ppcb ligand in 2 could be partially dedimerized to 3-spy with 68%completion through single-crystal-to-single-crystal(SCSC)transformation,giving the annealing complexes[Fe(3-spy)1.36(rctt-3-ppcb)0.32{Pd(CN)_(4)}](3)which display an incomplete SCO behavior.The 2■3 interconversion is successfully achieved via continuous UV irradiation and thermal annealing,demonstrating the effectiveness of photochemical[2+2]reaction on switching on-off SCO properties.

Ferroelectric polarization reversal tuned by magnetic field in a ferroelectric BiFeO3/Nb-doped SrTiO3 heterojunction

Interracial resistive switching of a ferroelectric semiconductor heterojunction is highly advantageous for the newly developed ferroelectric memristors. Moreover, the interfacial state in the ferroelectric semiconductor heterojunction can be gradually modified by polarization reversal, which may give rise to continuously tunable resistive switching behavior. In this work, the interfacial state of a ferroelectric BiFeO3/Nb-doped SrTiO3 junction was modulated by ferroelectric polarization reversal. The dynamics of surface screening charges on the BiFeO3 layer was also investigated by surface potential measure- ments, and the decay of the surface potential could be speeded up by the magnetic field. Moreover, ferroelectric polarization reversal of the BiFeO3 layer was tuned by the magnetic field. This finding could provide a method to enhance the ferroelectric and electrical properties of ferroelectric BiFeO3 films by tuning the magnetic field.