In this work, a two-dimensional numerical simulation of the discharge characteristics of helium plasma propagating inside a dielectric tube was performed. A trapezoidal ＋9 kV pulse lasting 400 ns was applied on a nee...In this work, a two-dimensional numerical simulation of the discharge characteristics of helium plasma propagating inside a dielectric tube was performed. A trapezoidal ＋9 kV pulse lasting 400 ns was applied on a needle electrode set inside the dielectric tube to ignite the discharge. The discharges generated in the tubes with a variable or a constant inner diameter were investigated.The focus of this study was on clarifying the effect of the tube diameter on the discharge structure and dynamics. The comparison of the discharge characteristics generated in dielectric tubes with different diameters was carried out. It was shown that the tube diameter plays a significant role in discharge behavior of plasma propagating in the dielectric tube.展开更多
Lung cancer remains the leading cause of cancer deaths worldwide and is the most common cancer in males.Immune-checkpoint inhibitors(ICIs)that target programmed cell death protein-1(PD-1)or programmed cell death-ligan...Lung cancer remains the leading cause of cancer deaths worldwide and is the most common cancer in males.Immune-checkpoint inhibitors(ICIs)that target programmed cell death protein-1(PD-1)or programmed cell death-ligand 1(PD-L1)have achieved impressive efficacy in the treatment of non-small-cell lung cancer(NSCLC)(Pardoll,2012;Champiat et al.,2016;Gao et al.,2022).Although ICIs are usually well tolerated,they are often accompanied by immune-related adverse events(irAEs)(Doroshow et al.,2019).Non-specific activation of the immune system produces off-target immune and inflammatory responses that can affect virtually any organ or system(O'Kane et al.,2017;Puzanov et al.,2017).展开更多
This study presents spatio-temporal development of the ionisation waves(IWs)along one dielectric tube with an extra alternating electric field.A pulsed direct current power supply is used for generating the IWs,and an...This study presents spatio-temporal development of the ionisation waves(IWs)along one dielectric tube with an extra alternating electric field.A pulsed direct current power supply is used for generating the IWs,and another alternating current power supply is used for altering the distribution of electric fields along the dielectric tube.The measurements show that the propagation velocity and density of IWs are strongly affected by the external electric field.The direct relation between external electric field and the velocity of the IWs is demonstrated.Further analysis indicates that the external electric field can be utilised to control the propagation of the IWs,resulting in a change of their density and velocity.展开更多
基金supported by National Natural Science Foundation of China(Nos.11705022,11505025,11705023)Innovation and Entrepreneurship Plan of Dalian Nationalities University(school-level A+Nos.201712026380)
文摘In this work, a two-dimensional numerical simulation of the discharge characteristics of helium plasma propagating inside a dielectric tube was performed. A trapezoidal ＋9 kV pulse lasting 400 ns was applied on a needle electrode set inside the dielectric tube to ignite the discharge. The discharges generated in the tubes with a variable or a constant inner diameter were investigated.The focus of this study was on clarifying the effect of the tube diameter on the discharge structure and dynamics. The comparison of the discharge characteristics generated in dielectric tubes with different diameters was carried out. It was shown that the tube diameter plays a significant role in discharge behavior of plasma propagating in the dielectric tube.
文摘Lung cancer remains the leading cause of cancer deaths worldwide and is the most common cancer in males.Immune-checkpoint inhibitors(ICIs)that target programmed cell death protein-1(PD-1)or programmed cell death-ligand 1(PD-L1)have achieved impressive efficacy in the treatment of non-small-cell lung cancer(NSCLC)(Pardoll,2012;Champiat et al.,2016;Gao et al.,2022).Although ICIs are usually well tolerated,they are often accompanied by immune-related adverse events(irAEs)(Doroshow et al.,2019).Non-specific activation of the immune system produces off-target immune and inflammatory responses that can affect virtually any organ or system(O'Kane et al.,2017;Puzanov et al.,2017).
基金the National Natural Science Foundation of China(NSFC-11475042,NSFC-11505025,NSFC-51377014 and NSFC-21573035).
文摘This study presents spatio-temporal development of the ionisation waves(IWs)along one dielectric tube with an extra alternating electric field.A pulsed direct current power supply is used for generating the IWs,and another alternating current power supply is used for altering the distribution of electric fields along the dielectric tube.The measurements show that the propagation velocity and density of IWs are strongly affected by the external electric field.The direct relation between external electric field and the velocity of the IWs is demonstrated.Further analysis indicates that the external electric field can be utilised to control the propagation of the IWs,resulting in a change of their density and velocity.
