Dear Editor,Growing evidences indicate that circRNAs affect hepatocellular carcinoma(HCC)progression.1,2,3,4 Understanding the roles of circRNAs in HCC recurrence helps develop innovated therapies.To identify novel HC...Dear Editor,Growing evidences indicate that circRNAs affect hepatocellular carcinoma(HCC)progression.1,2,3,4 Understanding the roles of circRNAs in HCC recurrence helps develop innovated therapies.To identify novel HCC recurrence-related circRNA,thirteen HCC patients were subjected to a multi-omics analysis of mRNA,circRNA.展开更多
基金This work was funded by National Natural Science Foundation of China(81520108021,91529305,81673250,and 81521091 to GC,and 81373067 to JY)Program of Shanghai Academic Research Leader(22XD1404800 to JY)the National Key Basic Research Program(973 program)(2015CB554000 to GC,and 2015CB554005 to JY).We acknowledge Dr.Mei Liu and Dr.Donghong Liu who took part in key experiments concerning ChIP-qPCR,subcellular localization of circGLS2 and western blot assays during revising this study.
文摘Dear Editor,Growing evidences indicate that circRNAs affect hepatocellular carcinoma(HCC)progression.1,2,3,4 Understanding the roles of circRNAs in HCC recurrence helps develop innovated therapies.To identify novel HCC recurrence-related circRNA,thirteen HCC patients were subjected to a multi-omics analysis of mRNA,circRNA.