In China,unity fosters diversity,and the diversity enriches the unity.The process of collision and integration was not aimed at eliminating each other but at enhancing each other,resulting in the emergence of a more i...In China,unity fosters diversity,and the diversity enriches the unity.The process of collision and integration was not aimed at eliminating each other but at enhancing each other,resulting in the emergence of a more inclusive civilization.展开更多
目的探讨不同时期难治性支原体肺炎(refractory mycoplasma pneumoniae pneumonia,RMPP)患儿支气管肺泡灌洗液中表面活性物质相关蛋白-A(surfactant protein A,SPA)的表达水平及与肺功能的关系。方法选取2021年1月—2023年1月南通市第...目的探讨不同时期难治性支原体肺炎(refractory mycoplasma pneumoniae pneumonia,RMPP)患儿支气管肺泡灌洗液中表面活性物质相关蛋白-A(surfactant protein A,SPA)的表达水平及与肺功能的关系。方法选取2021年1月—2023年1月南通市第一人民医院收治的62例RMPP患儿为对象,以同期行支气管镜异物取出术且无肺部感染的50例患儿为对照组。RMPP患儿于急性期、恢复期行支气管肺泡灌洗液中SPA检测以及肺功能指标检测[第1秒用力呼气容积(forced expiratory volume in one second,FEV_(1))、用力肺活量(forced vital capacity,FVC)、FEV_(1)/FVC],对照组同样如此。比较三者检测结果差异,使用Pearson分析RMPP患儿支气管肺泡灌洗液中SPA水平与肺功能指标的相关性。结果RMPP患儿肺泡灌洗液中的SPA急性期(59.82±12.64)μg/L、恢复期(129.91±24.86)μg/L高于对照组,差异有统计学意义(P<0.05)。RMPP急性期、RMPP恢复期的FEV_(1)、FVC、FEV_(1)/FVC(80.95±6.88)%、(88.41±5.75)%较对照组低,差异有统计学意义(P<0.05);RMPP患儿于急性期时肺泡灌洗液中的SPA较恢复期低,FEV_(1)、FVC、FEV_(1)/FVC较恢复期低,差异有统计学意义(P<0.05);RMPP患儿肺泡灌洗液中SPA水平与FEV_(1)、FVC、FEV_(1)/FVC呈正相关(P<0.05)。结论RMPP患儿病情处于急性发展阶段的情况下其支气管肺泡灌洗液中的SPA表达相较病情恢复阶段更低,同时RMPP患儿支气管肺泡灌洗液中SPA水平与其肺功能指标呈正相关性。展开更多
As total nitrogen(TN)and total phosphorus(TP)pollution is the main source of water pollution in the Huaihe River watershed in China,it is important to understand how TN and TP pollution affect the relationship between...As total nitrogen(TN)and total phosphorus(TP)pollution is the main source of water pollution in the Huaihe River watershed in China,it is important to understand how TN and TP pollution affect the relationship between water supply and demand.Quantifying their impacts and describing the spatiotemporal distribution of these relationships are necessary for furtherly deepening the theory of TN and TP pollution on water bodies,and this information is also particularly essential for managing water resources regionally.In this study,based on the potential water supply,the water demand and the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)water purification models,we estimated the TN and TP pollution from agricultural fertilizer,livestock and poultry breeding,and rural residents in the Huaihe River watershed and simulated TN and TP impacts on the relationship between water supply and demand.We found that if the impact of TN and TP pollution on water supply was not taken into account,on average,there was excess water supply in 79.20%of the watershed and excess demand in 20.80%of the rest during 1980–2018.Under the TN concentration limit,Grade-Ⅱ(The water quality meets the secondary level of water body qualified in GB3838–2002,classified as Grade-II)water was the main watersupply type in 1980–2018,followed by Grade-Ⅰ and Grade-Ⅲ water.The total water shortage showed an inverted V-shaped trend:first increasing and then decreasing at the same period.The proportion of the water shortage of Grade-I water in the total water shortage was the largest,followed by Grade-Ⅱ and Grade-III water.Areas with excess demand were located on the north bank of Wang-Beng,Yishuhe,and Huxi regions,although the water in these sub-watersheds met the water quality standards of Grade-Ⅰ water.Under the TP concentration limit,Grade-Ⅱ and Grade-Ⅰ water were the main water-supply types.The overall water shortage trend first increased and then decreased,exhibiting an inverted V-shape from 1980 to 2018.The water shortages of Grade-Ⅰ and Grade-Ⅱ water showed similar inverted V-shape trend over time.Areas that met the water quality standard of Grade-Ⅰ included the north banks of Wang-Beng and Huxi regions,where there was a surplus of demand.This paper suggests a way to analyze the interaction between water pollutants and the water supply-demand ratio as the example of TN and TP pollution at a watershed scale,which can broaden water pollution theory for relative water resources departments when water supply and demand will be evaluated.展开更多
文摘In China,unity fosters diversity,and the diversity enriches the unity.The process of collision and integration was not aimed at eliminating each other but at enhancing each other,resulting in the emergence of a more inclusive civilization.
文摘目的探讨不同时期难治性支原体肺炎(refractory mycoplasma pneumoniae pneumonia,RMPP)患儿支气管肺泡灌洗液中表面活性物质相关蛋白-A(surfactant protein A,SPA)的表达水平及与肺功能的关系。方法选取2021年1月—2023年1月南通市第一人民医院收治的62例RMPP患儿为对象,以同期行支气管镜异物取出术且无肺部感染的50例患儿为对照组。RMPP患儿于急性期、恢复期行支气管肺泡灌洗液中SPA检测以及肺功能指标检测[第1秒用力呼气容积(forced expiratory volume in one second,FEV_(1))、用力肺活量(forced vital capacity,FVC)、FEV_(1)/FVC],对照组同样如此。比较三者检测结果差异,使用Pearson分析RMPP患儿支气管肺泡灌洗液中SPA水平与肺功能指标的相关性。结果RMPP患儿肺泡灌洗液中的SPA急性期(59.82±12.64)μg/L、恢复期(129.91±24.86)μg/L高于对照组,差异有统计学意义(P<0.05)。RMPP急性期、RMPP恢复期的FEV_(1)、FVC、FEV_(1)/FVC(80.95±6.88)%、(88.41±5.75)%较对照组低,差异有统计学意义(P<0.05);RMPP患儿于急性期时肺泡灌洗液中的SPA较恢复期低,FEV_(1)、FVC、FEV_(1)/FVC较恢复期低,差异有统计学意义(P<0.05);RMPP患儿肺泡灌洗液中SPA水平与FEV_(1)、FVC、FEV_(1)/FVC呈正相关(P<0.05)。结论RMPP患儿病情处于急性发展阶段的情况下其支气管肺泡灌洗液中的SPA表达相较病情恢复阶段更低,同时RMPP患儿支气管肺泡灌洗液中SPA水平与其肺功能指标呈正相关性。
基金Under the auspices of the National Natural Science Foundation of China(No.71203200)the National Social Science Fund Project(No.20&ZD138)+1 种基金the National Science and Technology Platform Construction Project(No.2005DKA32300)Major Research Projects of the Ministry of Education(No.16JJD770019)。
文摘As total nitrogen(TN)and total phosphorus(TP)pollution is the main source of water pollution in the Huaihe River watershed in China,it is important to understand how TN and TP pollution affect the relationship between water supply and demand.Quantifying their impacts and describing the spatiotemporal distribution of these relationships are necessary for furtherly deepening the theory of TN and TP pollution on water bodies,and this information is also particularly essential for managing water resources regionally.In this study,based on the potential water supply,the water demand and the Integrated Valuation of Ecosystem Services and Tradeoffs(InVEST)water purification models,we estimated the TN and TP pollution from agricultural fertilizer,livestock and poultry breeding,and rural residents in the Huaihe River watershed and simulated TN and TP impacts on the relationship between water supply and demand.We found that if the impact of TN and TP pollution on water supply was not taken into account,on average,there was excess water supply in 79.20%of the watershed and excess demand in 20.80%of the rest during 1980–2018.Under the TN concentration limit,Grade-Ⅱ(The water quality meets the secondary level of water body qualified in GB3838–2002,classified as Grade-II)water was the main watersupply type in 1980–2018,followed by Grade-Ⅰ and Grade-Ⅲ water.The total water shortage showed an inverted V-shaped trend:first increasing and then decreasing at the same period.The proportion of the water shortage of Grade-I water in the total water shortage was the largest,followed by Grade-Ⅱ and Grade-III water.Areas with excess demand were located on the north bank of Wang-Beng,Yishuhe,and Huxi regions,although the water in these sub-watersheds met the water quality standards of Grade-Ⅰ water.Under the TP concentration limit,Grade-Ⅱ and Grade-Ⅰ water were the main water-supply types.The overall water shortage trend first increased and then decreased,exhibiting an inverted V-shape from 1980 to 2018.The water shortages of Grade-Ⅰ and Grade-Ⅱ water showed similar inverted V-shape trend over time.Areas that met the water quality standard of Grade-Ⅰ included the north banks of Wang-Beng and Huxi regions,where there was a surplus of demand.This paper suggests a way to analyze the interaction between water pollutants and the water supply-demand ratio as the example of TN and TP pollution at a watershed scale,which can broaden water pollution theory for relative water resources departments when water supply and demand will be evaluated.
