BACKGROUND Strongyloidiasis is usually a chronic infection but it can develop into a fatal disease in immunosuppressed patients.CASE SUMMARY A 68-year-old male with rheumatoid arthritis was treated with a variety of i...BACKGROUND Strongyloidiasis is usually a chronic infection but it can develop into a fatal disease in immunosuppressed patients.CASE SUMMARY A 68-year-old male with rheumatoid arthritis was treated with a variety of immunosuppressants for the past 3 years.Recently,the patient presented with a partial small-bowel obstruction,petechia,coughing and peripheral neuropathy.The diagnosis was difficult to clarify in other hospitals.Our hospital found Strongyloides stercoralis larvae with active movement in the routine stool and sputum smears.The diagnosis of disseminated strongyloidiasis was established.Ivermectin combined with albendazole was used for treatment.The patient responded to therapy and was discharged.CONCLUSION This case underscores the importance of comprehensive differential diagnosis in immunocompromised patients.展开更多
BACKGROUND This study describes the use of a moisture chamber to treat corneal ulceration due to temporary lagophthalmos in a critically ill patient.CASE SUMMARY A 46-year-old woman was admitted to the intensive care ...BACKGROUND This study describes the use of a moisture chamber to treat corneal ulceration due to temporary lagophthalmos in a critically ill patient.CASE SUMMARY A 46-year-old woman was admitted to the intensive care unit after a car accident.She suffered multiple injuries that included brain injury and presented with moderately decreased consciousness and lagophthalmos in her right eye.Within 6 d,her consciousness improved considerably;at which time,exposure keratopathy occurred and worsened to corneal ulceration.Lubricating gel,antibiotic ointment,and bandage contact lens were all ineffective in preventing or treating the exposure keratopathy.Instead of tarsorrhaphy,a moisture chamber was applied which successfully controlled the corneal ulceration.The moisture chamber was discontinued when complete eyelid closure recovered a week later.CONCLUSION A moisture chamber may be an effective,noninvasive alternative to tarsorrhaphy for treating severe exposure keratopathy due to temporary lagophthalmos.展开更多
文摘BACKGROUND Strongyloidiasis is usually a chronic infection but it can develop into a fatal disease in immunosuppressed patients.CASE SUMMARY A 68-year-old male with rheumatoid arthritis was treated with a variety of immunosuppressants for the past 3 years.Recently,the patient presented with a partial small-bowel obstruction,petechia,coughing and peripheral neuropathy.The diagnosis was difficult to clarify in other hospitals.Our hospital found Strongyloides stercoralis larvae with active movement in the routine stool and sputum smears.The diagnosis of disseminated strongyloidiasis was established.Ivermectin combined with albendazole was used for treatment.The patient responded to therapy and was discharged.CONCLUSION This case underscores the importance of comprehensive differential diagnosis in immunocompromised patients.
基金Supported by Huashan Hospital,Fudan University,No.2016QD03.
文摘BACKGROUND This study describes the use of a moisture chamber to treat corneal ulceration due to temporary lagophthalmos in a critically ill patient.CASE SUMMARY A 46-year-old woman was admitted to the intensive care unit after a car accident.She suffered multiple injuries that included brain injury and presented with moderately decreased consciousness and lagophthalmos in her right eye.Within 6 d,her consciousness improved considerably;at which time,exposure keratopathy occurred and worsened to corneal ulceration.Lubricating gel,antibiotic ointment,and bandage contact lens were all ineffective in preventing or treating the exposure keratopathy.Instead of tarsorrhaphy,a moisture chamber was applied which successfully controlled the corneal ulceration.The moisture chamber was discontinued when complete eyelid closure recovered a week later.CONCLUSION A moisture chamber may be an effective,noninvasive alternative to tarsorrhaphy for treating severe exposure keratopathy due to temporary lagophthalmos.
