腰果过敏原Ana o 2结构及抗原表位预测

腰果是引起人们过敏的主要食物之一。作者采用生物信息学方法,通过Pubmed网络服务器、生物信息分析软件SOPMA、swiss-model网络服务器、DNAStar生物分析软件等对腰果主要过敏原Ana o 2的结构和抗原表位进行预测,分析Ana o 2蛋白的抗原表位可能是108-111,181-186,217-218,234-238,244-255,283-287。这为腰果过敏原的进一步研究提供理论参考,并对开发低过敏腰果制品提供帮助。

2009-2018年江苏省太湖西岸主要入湖河道水质变化趋势

为了解太湖西岸主要入湖河流的水质变化趋势,选取陈东港、殷村港、太滆运河、大浦港、漕桥河5条主要入湖河流2009—2018年水质监测资料,通过氨氮、高锰酸盐指数、总磷和总氮质量浓度年际变化分析及季节性Kendall检验,分析5条主要入湖河流的水质变化趋势。

中华绒螯蟹病害应急预警系统设计

开发河蟹生态养殖病害应急预警系统,通过对河蟹病害的流行和发生进行监测,专家系统将病害的各种特征、迹象以及防范的措施等信息及时发送至示范区的养殖户,实现河蟹病害预警。应急预警系统保护养殖水体环境,在源头上保证了中华绒螯蟹的品质。

Study on intermittent irrigation for Paddy Rice: Ⅱ. Crop Responses

Effect of intermittent irrigation on the production of paddy rice was studied in a well-puddled paddy field with four treatments and 2 replicates: continuous flooding irrigation (CFI), and intermittent irrigation Ⅱ-O, Ⅱ-1 and Ⅱ-2, in which plants were re-irrigated when the soil water potential fell below 0, -10, and -20 kPa, respectively, at soil depth of about 5 cm. Results showed that the reduction in soil water potential to about -10 or -20 kPa did not significantly affect the number of grains and the percentage of ripened grains. While, a lower crop growth rate (CGR) resulted from a decrease in the net assimilation rate (NAR) during intermittent irrigation Ⅱ-1 and Ⅱ-2, and there was also a reduction in the leaf area index (LAI) during intermittent irrigation Ⅱ-2. Senescence of lower leaves on stems was promoted in treatments Ⅱ-1 and Ⅱ-2 at the ripening stage. Early senescence at ripening stage and water stress around midday decreased the rate of photosynthesis in leaves, causing the lower NAR. These physiological responses of the plants were responsible for the reduction in the dry matter production and grain yield in the intermittent irrigation treatments.

Coupled Transfer of Water and Heat in Red Soil: Experiment and Numerical Modelling

Coupled transfer of soil water and heat in closed columns of homogeneous red soil was studied under laboratory conditions. A coupled model was constructed using soil physical theory, empirical equations and experimental data to predict the coupled transfer. The results show that transport of soil water was affected by temperature gradient, and the largest net water transport was found in the soil column with initial water content of 0.148 m3 m-3. At the same time, temperature changes with the transport of soil water was in a nonlinear shape as heat parameters were function of water content, and the changes of temperature were positively correlated with the net amount of water transported. Numerical modelling results show that the predicted values of temperature distribution were close to the observed values, while the predicted values of water content exhibited limited deviation at both ends of the soil column due to the slight temperature changes at both ends. It was indicated that the model proposed here was applicable.

Adding analysis of urban heat island effect in GIS system and applying them in urban planning

In recent years, the application of GIS in urban planning has attracted the attention of more and more urban planning designers, and a new problem— urban heat island has arose in urban planning .The main aim of the paper is to find ways to connect urban heat environment with GIS system, and to simulate different island effect of different urban planning by using CFD. Then find a reasonable way for ecological urban planning .Of course, we firstly introduce the relation between the City Heat Island Effect and urban planning, then enumerate a practical experiment of Chongqing University. Because of people''s requirement of the better living environment and the ecological development of the whole city even the whole globe, we should synthesize and analyze the practical information, which base on the natural factors such as earth surface environment, climate, rainfall amount and wind field, and with these artificial factors such as population, politics and cultures, then design the optimum project of urban planning.

Study on Intermittent Irrigation for Paddy Rice: I. Water Use Efficiency

A field experiment was conducted in a well-puddled paddy field developed on the Tama River alluvial soil in the Farm of Tokyo University of Agriculture and Technology, Japan, to study the effect of intermittent irrigation on water use efficiency of paddy rice. Four treatments were arranged with 2 replicates: continuous flooding irrigation treatments (CFI), and three intermittent irrigation treatments Ⅱ-0, Ⅱ-1 and Ⅱ-2, in which plants were re-irrigated when the soil water potential fell below 0, -10, and -20 kPa, respectively, at soil depth of about 5 cm. Water consumption was lower in treatment Ⅱ-0 than in treatment CFI because the percolation rate was reduced by the reduction in the hydraulic head of ponded water. Intermittent irrigation led to soil repeated shrinking and swelling in Ⅱ-1 and Ⅱ-2 plots and, therefore, soil cracks developed rapidly. Since they became the major routes of water percolation, the soil cracks increased water consumption in treatments Ⅱ-1 and Ⅱ-2. There were no significant differences in dry matter production and grain yields between treatment Ⅱ-0 and treatment CFI, but the dry matter production and grain yields in treatments Ⅱ-0 and CFI were significantly higher than those in treatments Ⅱ-1 and Ⅱ-2. Therefore, the water use efficiency in the treatments was in the order of Ⅱ-0 > CFI > Ⅱ- 2 > Ⅱ- 1.

可视化技术在风电运维中的应用案例分析

随着我国风电行业的蓬勃发展,风电场不断增多,风电机组的数量也日益增加,运维后市场呈爆炸式发展,但这造成了运维后市场中有效资源的稀缺。为解决这一问题,介绍了2D和3D可视化技术在风电运维中的应用案例,涉及到风电运维体系中的各个方面。以期通过分析,助力可视化技术在风电运维工作中的深度开发与利用。

The Fast Blind Equalization Algorithm with Global Convergence

ＴｈｅＦａｓｔＢｌｉｎｄＥｑｕａｌｉｚａｔｉｏｎＡｌｇｏｒｉｔｈｍｗｉｔｈＧｌｏｂａｌＣｏｎｖｅｒｇｅｎｃｅＬｕＪｕｎＬｉＴｏｎｇ（ＩｎｓｔｉｔｕｔｅｏｆＩｎｆｏｒｍａｔｉｏｎａｎｄＥｎｇｉｎｅｅｒｉｎｇｏｆＰＬＡ，Ｚｈｅｎｇｚｈｏｕ４５０００２）Ａ...

Development of city water supply net information system

Through analyzing the present conditions of water supply networks technical administration files in Chongqing, this paper points out the significance and urgency for exploiting advanced water supply networks information system. It also gives the concept of GIS and some suggestions for the exploitation.

Cold rotation in the reaction ^(19)F+^(51)V

Ｃｏｌｄｒｏｔａｔｉｏｎｉｎｔｈｅｒｅａｃｔｉｏｎ１９Ｆ＋５１ＶＴｈｅＰｒｏｊｅｃｔＳｕｐｐｏｒｔｅｄｂｙＮａｔｉｏｎａｌＮａｔｕｒａｌＳｃｉｅｎｃｅＦｏｕｎｄａｔｉｏｎｏｆＣｈｉｎａ，ｔｈｅＮａｔｕｒａｌＳｃｉｅｎｃｅＦｏｕｎｄａｔｉｏｎｏｆＧ...

新辅助化疗期间肌肉指数变化值预测胃癌根治术预后的临床价值

目的探讨新辅助化疗期间肌肉指数变化值预测胃癌根治术预后的临床价值。方法采用回顾性队列研究方法。收集2010年1月至2017年12月3家医学中心收治的362例(福建医科大学附属协和医院163例、青海大学附属医院141例、圣玛丽亚医院58例)行新辅助化疗联合胃癌根治术病人的临床病理资料;男270例,女92例;中位年龄为61岁,年龄范围为26~79岁。362例病人中,福建医科大学附属协和医院与青海大学附属医院收治的304例病人设为建模组;圣玛丽亚医院收治的58例病人设为验证组。观察指标:(1)建模组病人行新辅助化疗期间身体成分、肿瘤标志物及应激状态指标变化情况。(2)随访及生存情况。(3)影响建模组病人预后因素分析。(4)预后预测模型的构建与比较。(5)预后预测模型评价。采用门诊、电话、信件方式进行随访,了解病人术后生存情况。随访时间截至2021年4月。正态分布的计量资料以x±s表示。偏态分布的计量资料以M(范围)表示。计数资料以绝对数表示。单因素和多因素分析采用COX比例风险模型。采用Kaplan-Meier法计算生存时间,采用Log-rank检验进行生存分析。结果(1)建模组病人行新辅助化疗期间身体成分、肿瘤标志物及应激状态指标变化情况。建模组304例病人行新辅助化疗前皮下脂肪指数、内脏脂肪指数、肌肉指数、癌胚抗原(CEA)、CA19-9、体质量指数(BMI)、预后营养指数(PNI)、修正全身炎症评分(mSIS)分别为31.2 cm^(2)/m^(2)(0.6~96.0 cm^(2)/m^(2)),25.1 cm^(2)/m^(2)(0.1~86.3 cm^(2)/m^(2)),47.1 cm^(2)/m^(2)(27.6~76.6 cm^(2)/m^(2)),43.2μg/L(0.2~1000.0μg/L),108.7 U/mL(0.6~1000.0 U/mL),21.9 kg/m^(2)(15.6~29.7 kg/m^(2)),46.8(28.6~69.0),(1.0±0.8)分;行胃癌根治术前上述指标分别为32.5 cm^(2)/m^(2)(5.1~112.0 cm^(2)/m^(2)),25.4 cm^(2)/m^(2)(0.2~89.0 cm^(2)/m^(2)),47.0 cm^(2)/m^(2)(16.8~67.0 cm^(2)/m^(2)),17.0μg/L(0.2~1000.0μg/L),43.9 U/mL(0.6~1000.0 U/mL),21.6 kg/m^(2)(31.1~29.0 kg/m^(2)),47.7(30.0~84.0),(1.0±0.8)分;行新辅助化疗期间上述指标变化值分别为1.4 cm^(2)/m^(2)(-31.0~35.1 cm^(2)/m^(2)),0.2 cm^(2)/m^(2)(-23.5~32.6 cm^(2)/m^(2)),-0.1 cm^(2)/m^(2)(-18.2~15.9 cm^(2)/m^(2)),-26.2μg/L(-933.5~89.9μg/L),-64.9 U/mL(-992.1~178.6 U/mL),-0.3 kg/m^(2)(-9.7~7.1 kg/m^(2)),0.9(-27.1~38.2),(0.0±0.8)分。(2)随访及生存情况。建模组304例病人中,284获得随访,随访时间为3~130个月,中位随访时间为36个月;随访期间,130例病人因肿瘤复发转移死亡,9例病人因非肿瘤原因死亡,病人5年总体生存率为54.6%。验证组58例病人中,52例获得随访,随访时间为2~91个月,中位随访时间为29个月;随访期间,21例病人死亡,病人5年总体生存率为63.8%。(3)影响建模组病人预后因素分析。单因素分析结果显示:术后病理学类型、术后病理学分期是影响建模组304例胃癌病人行胃癌根治术后5年总体生存率[风险比=1.685,2.619,95%可信区间(CI)为1.139~2.493,1.941~3.533,P<0.05]和5年疾病无进展生存率的相关因素(风险比=1.468,2.577,95%CI为1.000~2.154,1.919~3.461,P<0.05)。多因素分析结果显示:术后病理学类型、术后病理学分期是建模组304例病人行胃癌根治术后5年总体生存率的独立影响因素(风险比=1.508,2.287,95%CI为1.013~2.245,1.691~3.093,P<0.05);术后病理学分期是建模组304例病人行胃癌根治术后5年疾病无进展生存率的独立影响因素(风险比=2.317,95%CI为1.719~3.123,P<0.05)。(4)预后预测模型的构建与比较。304例建模组胃癌病人皮下脂肪指数变化值、内脏脂肪指数变化值、CEA变化值、CA19-9变化值、BMI变化值、PNI变化值、mSIS变化值预后预测模型受试者工作特征曲线下面积(AUC)分别为0.549(95%CI为0.504~0.593)、0.501(95%CI为0.456~0.546)、0.566(95%CI为0.521~0.610)、0.519(95%CI为0.474~0.563)、0.588(95%CI为0.545~0.632)、0.553(95%CI为0.509~0.597)、0.539(95%CI为0.495~0.584),与肌肉指数变化值预后预测模型AUC[0.661(95%CI为0.623~0.705)]比较,差异均有统计学意义(Z=3.960,5.326,3.353,4.786,2.455,3.448,3.987,P<0.05)。肌肉指数变化值预后预测模型最佳截点值为0.7 cm^(2)/m^(2),Kaplan-Meier生存曲线结果显示:建模组肌肉指数变化值<0.7 cm^(2)/m^(2)胃癌病人与肌肉指数变化值≥0.7 cm^(2)/m^(2)胃癌病人总体生存率和疾病无进展生存率比较,差异均有统计学意义(χ2=27.510,21.830,P<0.05)。选取肌肉指数变化值、术后病理学类型、术后病理学分期为预后指标,在建模组病人中构建肌肉指数变化值+术后病理学类型+术后病理学分期列线图预后预测模型,其在建模组和验证组的AUC分别为0.762(95%CI为0.708~0.815)和0.788(95%CI为0.661~0.885),术后病理学分期预后预测模型在建模组和验证组的AUC分别为0.706(95%CI为0.648~0.765)和0.727(95%CI为0.594~0.835),列线图预后预测模型与术后病理学分期预后预测模型建模组和验证组AUC比较,差异均有统计学意义(Z=3.522,1.830,P<0.05)。(5)预后预测模型评价。肌肉指数变化值+术后病理学类型+术后病理学分期列线图预后预测模型结果显示:列线图风险评分0~6分为低风险,评分>6分且≤10分为中低风险,评分>10分且≤13分为中高风险,评分>13分为高危风险。Kaplan-Meier生存曲线结果显示:建模组及验证组低风险、中低风险、中高风险、高风险病人总体生存率比较,差异均有统计学意义(χ^(2)=75.276,14.989,P<0.05)。决策曲线分析结果显示:在建模组和验证组中,肌肉指数变化值+术后病理学类型+术后病理学分期列线图预后预测模型预测性能优于术后病理学分期预后预测模型。结论新辅助化疗期间病人肌肉指数变化值可作为胃癌根治术后病人预后预测指标,肌肉指数变化值+术后病理学类型+术后病理学分期列线图风险评分可评估病人行胃癌根治术后生存预后。

Original component of grain size index in core sediment from southwestern slope of the South China Sea and its paleoenvironmental implication

A new approach to the basic composition char- acter of deep sea sediment is discussed in this paper for indi- cating its paleoenvironment meaning. For this purpose high precision grain size character of sediments from core NS93-5 was analysed by using the Laser Diffraction Particle Size Analyzer, combining with results of micropalaeontologic counting and trace element and calcium carbonate testing, to illustrate some main grain size indexes and their relationship with micropalaeontologic makeup and terrigenous input. It was showed that the grain sizes of deep sea sediment may reflect materials properties and their buildup framework. There are obvious relations between indexes of grain size ranges and abundances of different micropalaeontologic groups and terrigenous matters, in which grain size of <2 μm represents terrigenous composition, that of >5 μm is mainly made up of various microfossil shells, except for containing volcanic dust layers, and median diameter (MD) of grain size may be taken as proxy of paleoproductivity or paleoecologi- cal dynamic. These index and proxy were consistent with micropaleontologic records for well indicating important features of paleoceanographic ecology, showing that the mi- cropalaeontologic growth in the southwestern slope area of the South China Sea (SCS) was negatively correlated to ter- rigenous input since late Pleistocene and corresponded to glacial-interglacial global climatic changes incompletely, but had a regional particularity in this sea area.

Construct 2D nanostructure of co-adsorbed dipyridyl derivative by stabilization of hydrogen bond and long alkyl chains

The self-assembled structures of 4, 4′-dionoyl-2, 2′-dipyridyl and its co-adsorption with stearic acid on highly oriented pyrolytic graphite (HOPG) have been studied by the scanning tunneling microscopy (STM). As a result, 4,4′- dionoyl-2,2′-dipyridyl forms a planar trans conformation in two cases, and through the co-adsorption with stearic acid, 4, 4′-dionoyl-2,2′-dipyridyl and stearic acid form a well-or- dered nanostructure.