Frailty is a multidimensional dynamic condition characterized by decreased physiological reserves. Therefore,frail people are more vulnerable to stressors.Indeed,minor stimuli,like a new drug prescription,can alter th...Frailty is a multidimensional dynamic condition characterized by decreased physiological reserves. Therefore,frail people are more vulnerable to stressors.Indeed,minor stimuli,like a new drug prescription,can alter their homeostatic equilibrium determining adverse clinical outcomes(i.e.,falls,institutionalization,disability,and death).[1,2]Since the risk of atrial fibrillation[3]and venous thromboembolism[4]increase with ageing,frail people might require long term anticoagulation.展开更多
文摘Frailty is a multidimensional dynamic condition characterized by decreased physiological reserves. Therefore,frail people are more vulnerable to stressors.Indeed,minor stimuli,like a new drug prescription,can alter their homeostatic equilibrium determining adverse clinical outcomes(i.e.,falls,institutionalization,disability,and death).[1,2]Since the risk of atrial fibrillation[3]and venous thromboembolism[4]increase with ageing,frail people might require long term anticoagulation.