Bladder tumor is characterized by recurrent recurrence and distant metastasis,which determines the difficulty of completely curing bladder tumor.In recent years,the number of patients with bladder cancer is increasing...Bladder tumor is characterized by recurrent recurrence and distant metastasis,which determines the difficulty of completely curing bladder tumor.In recent years,the number of patients with bladder cancer is increasing,and the treatment of bladder cancer has become an important direction of clinical research.It is difficult to control bladder tumor by traditional therapy.Photodynamic therapy(PDT),as a new optical therapy,has gradually become the main method in clinical treatment of bladder tumor combined with transurethral resection of bladder tumor.In this paper,a patient with superficial recurrent bladder tumor was treated by photodynamic therapy combined with transurethral resection of bladder tumor.The advantages of photodynamic therapy in the treatment of bladder tumor and the selection of photosensitizer in the process of photodynamic therapy were discussed.After two recurrences,the patients chose photodynamic therapy.The tumors were resected one by one,and the wound was coagulated by roller electrode.After the drug was retained for 20 minutes,the bladder was empty.The spherical optical fiber was implanted into the bladder.The photodynamic energy was adjusted(light power 1.8 W,light time 1302 s).There was no recurrence after operation.Most bladder tumors are superficial tumors,and bladder is a cavity organ,which determines that bladder is an ideal organ for photodynamic therapy.As a targeted drug,photosensitizer is only absorbed by bladder tumor after being perfused into bladder.The photosensitizer forms reactive oxygen species through oxygen and kills tumor cells.Clinical practice has proved that PDT has its unique advantages for superficial and recurrent bladder tumors.As the first generation photosensitizer,xipofen also has selectivity in the treatment of bladder cancer.展开更多
Background and Study Aims:To observe the efficacy of photodynamic therapy in patients with advanced gastric cancer and analyze the reasons affecting the efficacy.Methods:In this paper,a patient with advanced gastric c...Background and Study Aims:To observe the efficacy of photodynamic therapy in patients with advanced gastric cancer and analyze the reasons affecting the efficacy.Methods:In this paper,a patient with advanced gastric cancer in our hospital was selected.HoPorfin is used as a photosensitizer and photodynamic therapy was performed 48 hours and 72 hours later.Results:One month after the photodynamic treatment,the patient came to our hospital to reexamine the gastroscope.Through the comparison of gastroscopy before and after the photodynamic treatment,the gastric cancer lesion of the patient after the photodynamic treatment was not significantly smaller than before,and the effect of photodynamic treatment was not ideal.Conclusion:The four reasons for the unsatisfactory effect:individual differences of patients,photosensitizer,light source and oxygen.展开更多
文摘Bladder tumor is characterized by recurrent recurrence and distant metastasis,which determines the difficulty of completely curing bladder tumor.In recent years,the number of patients with bladder cancer is increasing,and the treatment of bladder cancer has become an important direction of clinical research.It is difficult to control bladder tumor by traditional therapy.Photodynamic therapy(PDT),as a new optical therapy,has gradually become the main method in clinical treatment of bladder tumor combined with transurethral resection of bladder tumor.In this paper,a patient with superficial recurrent bladder tumor was treated by photodynamic therapy combined with transurethral resection of bladder tumor.The advantages of photodynamic therapy in the treatment of bladder tumor and the selection of photosensitizer in the process of photodynamic therapy were discussed.After two recurrences,the patients chose photodynamic therapy.The tumors were resected one by one,and the wound was coagulated by roller electrode.After the drug was retained for 20 minutes,the bladder was empty.The spherical optical fiber was implanted into the bladder.The photodynamic energy was adjusted(light power 1.8 W,light time 1302 s).There was no recurrence after operation.Most bladder tumors are superficial tumors,and bladder is a cavity organ,which determines that bladder is an ideal organ for photodynamic therapy.As a targeted drug,photosensitizer is only absorbed by bladder tumor after being perfused into bladder.The photosensitizer forms reactive oxygen species through oxygen and kills tumor cells.Clinical practice has proved that PDT has its unique advantages for superficial and recurrent bladder tumors.As the first generation photosensitizer,xipofen also has selectivity in the treatment of bladder cancer.
文摘Background and Study Aims:To observe the efficacy of photodynamic therapy in patients with advanced gastric cancer and analyze the reasons affecting the efficacy.Methods:In this paper,a patient with advanced gastric cancer in our hospital was selected.HoPorfin is used as a photosensitizer and photodynamic therapy was performed 48 hours and 72 hours later.Results:One month after the photodynamic treatment,the patient came to our hospital to reexamine the gastroscope.Through the comparison of gastroscopy before and after the photodynamic treatment,the gastric cancer lesion of the patient after the photodynamic treatment was not significantly smaller than before,and the effect of photodynamic treatment was not ideal.Conclusion:The four reasons for the unsatisfactory effect:individual differences of patients,photosensitizer,light source and oxygen.
