Objective: To explore whether the deqi effect affects the effectiveness of manual acupuncture for treating knee osteoarthritis by a network meta-analysis(NMA).Methods: Eight databases were searched for relevant publis...Objective: To explore whether the deqi effect affects the effectiveness of manual acupuncture for treating knee osteoarthritis by a network meta-analysis(NMA).Methods: Eight databases were searched for relevant published studies since inception through January 2021. Randomized control trials that compared manual acupuncture with deqi, manual acupuncture without deqi, and conventional treatment of western medicine were included. Languages were limited to English and Chinese. Two authors independently selected eligible studies, assessed methodological quality and the effects of deqi, and extracted outcome data. The mean difference(MD) and standardized mean differences(SMDs) with 95% confidence intervals(CIs) were calculated by Stata 15.0 to conduct an NMA based on a frequentist framework.Results: Fourteen trials with a total of 1868 subjects were included. The direct and indirect comparisons were authentic, according to inconsistency tests. The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) pooled results indicated that there was no significant effect of deqi(SMD=-0.23, 95% CI [-0.81, 0.35]). The pooled results of visual analogue scale(VAS) were similar to those of WOMAC(MD=-0.53, 95% CI [-1.03, 0.02]).Conclusion: As a summary of the currently available research, the NMA results indicated that deqi effect might not be the crucial factor for the effectiveness of manual acupuncture.展开更多
The authors regret<In previous version,we made several errors.The correct descriptions are as follows.>.[Results]They used manual stimulation of the needles:one clearly required deqi in the intervention method;6...The authors regret<In previous version,we made several errors.The correct descriptions are as follows.>.[Results]They used manual stimulation of the needles:one clearly required deqi in the intervention method;6 one achieved deqi if possible;14 one executed a brief manipulation at the beginning and the end of the treatment;31 and 10 RCTs described the manipulation to elicit deqi.29,30,32-39 In three MAOD groups,one used Streitberger non-penetrating needle,31 the patients in Wang et al.’s experiment were given fine needle,shallow insertion and weak stimulation without manipulation to avoid Deqi,32 whereas other one used needle inserted into acupoints but did not use any method of stimulation.40 In the CTWM,11 RCTs included routine pharmacological therapy,and one RCT14 considered waiting lists in which patients were allowed to receive oral NSAIDs if necessary.Twelve RCTs recorded WOMAC,and ten RCTs used VAS.展开更多
基金supported by the Key Project of Central University Funding(2020-JYB-ZDGG-066)。
文摘Objective: To explore whether the deqi effect affects the effectiveness of manual acupuncture for treating knee osteoarthritis by a network meta-analysis(NMA).Methods: Eight databases were searched for relevant published studies since inception through January 2021. Randomized control trials that compared manual acupuncture with deqi, manual acupuncture without deqi, and conventional treatment of western medicine were included. Languages were limited to English and Chinese. Two authors independently selected eligible studies, assessed methodological quality and the effects of deqi, and extracted outcome data. The mean difference(MD) and standardized mean differences(SMDs) with 95% confidence intervals(CIs) were calculated by Stata 15.0 to conduct an NMA based on a frequentist framework.Results: Fourteen trials with a total of 1868 subjects were included. The direct and indirect comparisons were authentic, according to inconsistency tests. The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC) pooled results indicated that there was no significant effect of deqi(SMD=-0.23, 95% CI [-0.81, 0.35]). The pooled results of visual analogue scale(VAS) were similar to those of WOMAC(MD=-0.53, 95% CI [-1.03, 0.02]).Conclusion: As a summary of the currently available research, the NMA results indicated that deqi effect might not be the crucial factor for the effectiveness of manual acupuncture.
文摘The authors regret<In previous version,we made several errors.The correct descriptions are as follows.>.[Results]They used manual stimulation of the needles:one clearly required deqi in the intervention method;6 one achieved deqi if possible;14 one executed a brief manipulation at the beginning and the end of the treatment;31 and 10 RCTs described the manipulation to elicit deqi.29,30,32-39 In three MAOD groups,one used Streitberger non-penetrating needle,31 the patients in Wang et al.’s experiment were given fine needle,shallow insertion and weak stimulation without manipulation to avoid Deqi,32 whereas other one used needle inserted into acupoints but did not use any method of stimulation.40 In the CTWM,11 RCTs included routine pharmacological therapy,and one RCT14 considered waiting lists in which patients were allowed to receive oral NSAIDs if necessary.Twelve RCTs recorded WOMAC,and ten RCTs used VAS.
