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Task Assignment Problem of Robots in a Smart Warehouse Environment 被引量:1
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作者 Zhenping Li Wenyu Li lulu jiang 《Management Studies》 2016年第4期167-175,共9页
The task assignment problem of robots in a smart warehouse environment (TARSWE) based on cargo-to-person is investigated. Firstly, the sites of warehouse robots and the order picking tasks are given and the task ass... The task assignment problem of robots in a smart warehouse environment (TARSWE) based on cargo-to-person is investigated. Firstly, the sites of warehouse robots and the order picking tasks are given and the task assignment problem for picking one order is formulated into a mathematical model to minimize the total operation cost. Then a heuristic algorithm is designed to solve the task assignment problem for picking multiple orders. Finally, simulations are done by using the orders data of online bookstore A. The results show that using the heuristic algorithm of this paper to assign robots, the cost was reduced by 2% and it can effectively avoid far route and unbalanced workload of robots. The feasibility and validity of the model and algorithm are verified. The model and algorithm in this paper provide a theoretical basis to solve the TARSWE. 展开更多
关键词 smart warehouse ROBOTS cargo-to-person task assignment mathematical model heuristic algorithm
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人口神经科学数据共享:政策生态、基础设施、实践和挑战
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作者 姜璐璐 高鹏 周园春 《科学通报》 EI CAS CSCD 北大核心 2024年第24期3560-3577,共18页
随着开放科学时代的到来,全球的数据共享政策日趋完善,科学数据共享逐步成为学术交流的必选项.科研模式及学术交流模式正发生着深刻的变革,如何让科学数据开放共享可持续发展,依然面临着来自文化、政策与实践路径上的现实阻力和挑战.本... 随着开放科学时代的到来,全球的数据共享政策日趋完善,科学数据共享逐步成为学术交流的必选项.科研模式及学术交流模式正发生着深刻的变革,如何让科学数据开放共享可持续发展,依然面临着来自文化、政策与实践路径上的现实阻力和挑战.本文梳理了科学数据开放共享可持续发展的必要组成及彼此间的作用关系,分析了利益相关方在数据共享中的诉求与需要付诸的投入.接着,从各方主体的科学数据共享政策情况、科学数据共享的标准及原则、数据存储库的标准规范指南、人口神经科学领域数据存储平台建设实践情况等方面,结合我国“科学数据银行:中国人彩巢计划数据社区”进行具体介绍与特征分析.人口神经科学领域的快速发展在很大程度上得益于科学数据共享,但依然面临着来自隐私安全与伦理,数据共享激励机制缺失,科研群体科学数据管理素质不足等突出问题和挑战.其中,伴随着新型科学技术的发展,隐私安全正被不断地完善和保护.针对科学数据共享的发展现状及挑战,本文基于在数据共享的政策、建立激励机制、基础设施建设、跨学科融合发展等方面的研究提出人口神经科学在科学数据共享工作上的未来发展趋势与建议. 展开更多
关键词 科学数据共享 数据政策 数据标准规范 科学数据银行 数据社区
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Aerodynamic/control integrated optimization method for unpowered high-speed vehicle configuration design
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作者 Xin PAN Linlin WANG +2 位作者 Li LI lulu jiang Gang CHEN 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第7期153-167,共15页
The unpowered high-speed vehicle experiences a significant coupling between the disciplines of aerodynamics and control due to its characteristics of high flight speed and extensive maneuverability within large airspa... The unpowered high-speed vehicle experiences a significant coupling between the disciplines of aerodynamics and control due to its characteristics of high flight speed and extensive maneuverability within large airspace.The conventional aircraft conceptual design process follows a sequential design approach,and there is an artificial separation between the disciplines of aerodynamics and control,neglecting the coupling effects arising from their interaction.As a result,this design process often requires extensive iterations over long periods when applied to high-speed vehicles,and may not be able to effectively achieve the desired design objectives.To enhance the overall performance and design efficiency of high-speed vehicles,this study integrates the concept of Active Control Technology(ACT)from modern aircraft into the philosophy of aerodynamic/control integrated optimization.Two integrated optimization strategies,with differences in coupling granularity,have been developed.Subsequently,these strategies are put into action on a biconical vehicle that operates at Mach 5.The results reveal that the comprehensive performance of the synthesis optimal model derived from the aerodynamic/control integrated optimization strategy is improved by 31.76%and 28.29%respectively compared to the base model under high-speed conditions,demonstrating the feasibility and effectiveness of the method and optimization strategies employed.Moreover,in comparison to the single-stage strategy,the multi-stage strategy takes into deeper consideration the impact of control capacity.As a result,the control performance of the synthesis opti-mal model derived from the multi-stage strategy improves by 13.99%,whereas the single-stage strategy only achieves a 5.79%improvement.This method enables a fruitful interaction between aerodynamic configuration design and control system design,leading to enhanced overall performance and design efficiency.Furthermore,it improves the controllability of high-speed vehicles,mitigating the risk of mission failure resulting from an ineffective control system. 展开更多
关键词 Aerodynamic/Control Integrated Optimization MDO High-speed vehicle Shape Optimization Controllability
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Corrigendum to“Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice”[Journal of Genetics and Genomics(2023)50,122-125]
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作者 Cheng Cheng Jieyu Qi +11 位作者 Liyan Zhang He Li Jie Lu Siyu Li Zhong Zhang Yue Qiu Chen Zhang lulu jiang Chaorong Yu Xia Gao Philip I.Bird Renjie Chai 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2023年第6期458-458,共1页
This corrigendum clarifies information in the article"Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice"by Cheng et al.(2023).In the author list,the author"Cheng Cheng... This corrigendum clarifies information in the article"Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice"by Cheng et al.(2023).In the author list,the author"Cheng Cheng"should be corrected into"Cheng Cheng". 展开更多
关键词 al. COR HEARING
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Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice
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作者 Cheng Cheng Jieyu Qi +11 位作者 Liyan Zhang He Li Jie Lu Siyu Li Zhong Zhang Yue Qiu Chen Zhang lulu jiang Chaorong Yu Xia Gao Phillip I.Bird Renjie Chai 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2023年第2期122-125,共4页
Hearing impairment constitutes a global public health problem with severe social,political,and economic consequences,and the World Health Organization estimates that about 466 million individuals globally have some de... Hearing impairment constitutes a global public health problem with severe social,political,and economic consequences,and the World Health Organization estimates that about 466 million individuals globally have some degree of hearing loss.Genetic factors account for about half of all deafness cases.Currently,more than 100 genes are known to be involved in hearing loss,but the underlying molecular mechanisms behind these deafness genes have not been fully characterized.The main clinical treatment for deafness is hearing aids and cochlear implants,but their efficacy depends heavily on the quantity and quality of residual hair cells(HCs)and spiral ganglion neurons and has only limited auditory effects. 展开更多
关键词 DEAFNESS AUDITORY HEARING
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Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy
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作者 Jian Zhao lulu jiang +6 位作者 Alex Matlock Yihong Xu Jiabei Zhu Hongbo Zhu Lei Tian Benjamin Wolozin Ji-xin Cheng 《Light(Science & Applications)》 SCIE EI CSCD 2023年第7期1354-1369,共16页
Amyloid proteins are associated with a broad spectrum of neurodegenerative diseases.However,it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native c... Amyloid proteins are associated with a broad spectrum of neurodegenerative diseases.However,it remains a grand challenge to extract molecular structure information from intracellular amyloid proteins in their native cellular environment.To address this challenge,we developed a computational chemical microscope integrating 3D midinfrared photothermal imaging with fluorescence imaging,termed Fluorescence-guided Bond-Selective Intensity Diffraction Tomography(FBS-IDT).Based on a low-cost and simple optical design,FBS-IDT enables chemical-specific volumetric imaging and 3D site-specific mid-IR fingerprint spectroscopic analysis of tau fbrils,an important type of amyloid protein aggregates,in their intracellular environment.Label-free volumetric chemical imaging of human cells with/without seeded tau fibrils is demonstrated to show the potential correlation between lipid accumulation and tau aggregate formation.Depth-resolved mid-infrared fingerprint spectroscopy is performed to reveal the protein secondary structure of the intracellular tau fibrils.3D visualization of theβ-sheet for tau fibril structure is achieved. 展开更多
关键词 TAU AMYLOID chemical
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Effect of Different Geometric Porosities on Aerodynamic Characteristics of Supersonic Parachutes
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作者 lulu jiang He Jia +5 位作者 Xin Xu Wei Rong Qi Wang Gang Chen Jianhui Fan Xiaopeng Xue 《Space(Science & Technology)》 EI 2023年第1期429-439,共11页
The supersonic parachute plays an important role in the descent and landing of Mars missions.Next-generation supersonic parachutes,such as disksail parachutes,are alternatives to disk-gap-band(DGB)parachutes.Disksail ... The supersonic parachute plays an important role in the descent and landing of Mars missions.Next-generation supersonic parachutes,such as disksail parachutes,are alternatives to disk-gap-band(DGB)parachutes.Disksail parachutes have larger porous gaps and smaller porous seams on the canopy surface than DGB parachutes.To date,the influence mechanism of porous seams or gaps and their locations on the performance of supersonic parachute systems in Martian atmospheric conditions remains unclear.In this study,different canopy models with seams and gaps based on NASA’s supersonic disksail parachutes were designed,and the aerodynamic characteristics of such geometric porosity models were studied numerically.For seam-only models,the drag coefficient of the parachute decreases when the position of the seam is close to the middle of the canopy.When the seam is close to the mouth of the canopy,the pressure difference between the inner and outer surface of the canopy becomes small,reducing the risk of tearing the canopy.For gap-only models,the drag coefficient of the middle gap model is higher,while the lateral force stability of the top gap model is better.The results show that the addition of a seam can improve the drag performance of the top gap model and improve the lateral stability of the canopy with the middle gap.This study provides some theoretical references for designing the porosity of parachutes under different requirements for Mars exploration missions in the future. 展开更多
关键词 POROSITY POROUS STABILITY
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I3:A Self-organising Learning Workflow for Intuitive Integrative Interpretation of Complex Genetic Data 被引量:1
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作者 Yun Tan lulu jiang +1 位作者 Kankan Wang Hai Fang 《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2019年第5期503-510,共8页
We propose a computational workflow(I3)for intuitive integrative interpretation of complex genetic data mainly building on the self-organising principle.We illustrate the use in interpreting genetics of gene expressio... We propose a computational workflow(I3)for intuitive integrative interpretation of complex genetic data mainly building on the self-organising principle.We illustrate the use in interpreting genetics of gene expression and understanding genetic regulators of protein phenotypes,particularly in conjunction with information from human population genetics and/or evolutionary history of human genes.We reveal that loss-of-function intolerant genes tend to be depleted of tissue-sharing genetics of gene expression in brains,and if highly expressed,have broad effects on the protein phenotypes studied.We suggest that this workflow presents a general solution to the challenge of complex genetic data interpretation.I3 is available at http://suprahex.r-forge.r-project.org/I3.html. 展开更多
关键词 Self-organising Human GENETICS INTERPRETATION Evolution Machine LEARNING
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Simultaneous bioimaging of MMP-2 and MMP-7 via Au-Se constructed fluorescence nanoprobe 被引量:1
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作者 Xiaonan Gao Wenfei Guo +4 位作者 lulu jiang Bo Hu Xiaojun Liu Kehua Xu Bo Tang 《Science China Chemistry》 SCIE EI CAS CSCD 2020年第1期135-140,共6页
Au-Se bond strategy has been applied to construct fluorescence nanoprobe that is being used to simultaneously dual-image the tumor markers matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-7(MMP-7)in vitro... Au-Se bond strategy has been applied to construct fluorescence nanoprobe that is being used to simultaneously dual-image the tumor markers matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-7(MMP-7)in vitro.The two Se-terminating ligand peptide chains respectively labeled with fluorescein isothiocyanate(FITC)and 5-Carboxytetramethylrhodamine(5-TAMRA)dyes are attached to the surface of Au nanoparticles(NPs).The nanoprobe can be specifically cut off by MMP-2 and MMP-7 respectively to carry out significant enhanced fluorescence recovery for simultaneously imaging both markers.The nanoprobe not only displays high selectivity and sensitivity towards MMP-2 and MMP-7,but also has strong anti-interference stability against biothiols and enhanced fidelity for avoiding"false positive"results.This approach offers new perspectives in designing tumor-related early diagnosis approaches and also provides strategies for clinical applications. 展开更多
关键词 fluorescence nanoprobe dual detection tumor markers fluorescence imaging Au nanoparticles
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Numerical Study on Aerodynamic Performance of Mars Parachute Models with Geometric Porosities 被引量:1
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作者 lulu jiang He Jia +5 位作者 Xin Xu Wei Rong Wei jiang Qi Wang Gang Chen Xiaopeng Xue 《Space(Science & Technology)》 2022年第1期338-350,共13页
The supersonic flows around rigid parachute-like two-body configurations are numerically simulated at Mach number of 1.978 by solving three-dimensional compressible Navier-Stokes equations,where the two-body model con... The supersonic flows around rigid parachute-like two-body configurations are numerically simulated at Mach number of 1.978 by solving three-dimensional compressible Navier-Stokes equations,where the two-body model consists of a capsule and a canopy,and a geometric structure(i.e.,gap)is located on the canopy surface.The objective of this study is to investigate the effects of gaps with different porosities and positions on the aerodynamic performance of supersonic parachute.The complicated periodic aerodynamic interactions between the capsule wake and canopy shock occur around these two-body models.From the formation of canopy shock and drag coefficient variation,the cycled flow structures can be divided into three types:(1)narrow wake period,(2)open wake period,and(3)middle wake period.In addition,it was found that the geometric gaps have no obvious influences on the flow modes.However,compared with models with different gap positions,the two-body model with an upper gap(gap is close to the canopy vent,UG model)has a smaller drag coefficient fluctuation and better lateral stability.On the other side,the increase of porosity has a more significant impact on UG models. 展开更多
关键词 stability surface POSITIONS
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