Dear Editor,In development,after cells make a commitment to their fates,they undergo a continuous and adaptive maturation process to eventually reach their terminal states.Cell maturity often decays during aging and p...Dear Editor,In development,after cells make a commitment to their fates,they undergo a continuous and adaptive maturation process to eventually reach their terminal states.Cell maturity often decays during aging and pathogenesis.The immature phenotypes of stem cell-differentiated cells deposit a major bottleneck in regenerative medicine.展开更多
基金supported by the National Key Research and Development Program of China (2022YFA1104800)the National Natural Science Foundation of China (82222006,32100660,82170367)+5 种基金Beijing Nova Program (Z211100002121003,20220484205)Beijing Natural Science Foundation (7232094)supported by National Institute of Health (R01HL146634 and UM1HL098166)supported by the Natural Science Foundation of China (82070235 and 92168113)the CAMS Innovation Fund for Medical Sciences (2021-I2M-5003)Haihe Laboratory of Cell Ecosystem Innovation Fund (HH22KYZX0047)。
文摘Dear Editor,In development,after cells make a commitment to their fates,they undergo a continuous and adaptive maturation process to eventually reach their terminal states.Cell maturity often decays during aging and pathogenesis.The immature phenotypes of stem cell-differentiated cells deposit a major bottleneck in regenerative medicine.
